Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anthony J. Domma"'
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT The protein kinase Akt broadly impacts many cellular processes, including mRNA translation, metabolism, apoptosis, and stress responses. Inhibition of phosphatidylinositol 3-kinase (PI3K), a lipid kinase pivotal to Akt activation, triggers v
Externí odkaz:
https://doaj.org/article/8fbf4a27abd64318a053b6635d1076ae
Publikováno v:
bioRxiv
The phosphoinositide 3-kinase (PI3K)/AKT pathway plays crucial roles in cell viability and protein synthesis and is frequently co-opted by viruses to support their replication. Although many viruses maintain high levels of AKT activity during infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0d2db0e9d8d67c608bd4e9af900d7a
https://europepmc.org/articles/PMC10153195/
https://europepmc.org/articles/PMC10153195/
The human cytomegalovirus (HCMV) endoplasmic reticulum (ER)-resident glycoprotein UL148 is posited to play roles in immune evasion and regulation of viral cell tropism. UL148 prevents cell surface presentation of the immune cell costimulatory ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d531cefd634dbcbd1b6bd0c5980a9ad9
Publikováno v:
J Virol
The human cytomegalovirus (HCMV) endoplasmic reticulum (ER)-resident glycoprotein UL148 is posited to play roles in immune evasion and regulation of viral cell tropism. UL148 prevents cell surface presentation of the immune cell costimulatory ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c5b9ab1b75f7317af93f97d88273d9
https://pubmed.ncbi.nlm.nih.gov/31801856
https://pubmed.ncbi.nlm.nih.gov/31801856
Autor:
Hongbo Zhang, Christopher C. Nguyen, Anthony J. Domma, Jeremy P. Kamil, Mohammed N. A. Siddiquey
Eukaryotic cells are equipped with three sensors that respond to the accumulation of misfolded proteins within the lumen of the endoplasmic reticulum (ER) by activating the unfolded protein response (UPR), which functions to resolve proteotoxic stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2a101c267375e2c619671746ca8d49
https://europepmc.org/articles/PMC6158444/
https://europepmc.org/articles/PMC6158444/
Autor:
Mohammed N. A. Siddiquey, Anthony J. Domma, Hongbo Zhang, Jeremy P. Kamil, Christopher C. Nguyen
Eukaryotic cells are equipped with three sensors that respond to the accumulation of misfolded proteins within the lumen of the endoplasmic reticulum (ER) by activating the unfolded protein response (UPR), which functions to resolve proteotoxic stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a148ea6603861dfe0031187f9965cf
https://doi.org/10.1101/328955
https://doi.org/10.1101/328955