Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Anthony J. Convertine"'
Publikováno v:
Polymer Chemistry. 14:1085-1093
Polysorbate 80 (PS80) was reacted with 3-mercaptopropyl trimethoxysilane (SiSH) via a photoinitiated thiol-ene reaction. The resulting conjugate was co-condensed with SiSH to form stable aqueous solutions of thiol-functional nanoparticles (TFNs).
Autor:
Aaron Priester, Richard Waters, Ashleigh Abbott, Krista Hilmas, Klaus Woelk, Hunter A. Miller, Aria W. Tarudji, Connor C. Gee, Brandon McDonald, Forrest M. Kievit, Anthony J. Convertine
Publikováno v:
Biomacromolecules
Traumatic brain injury (TBI) results in the generation of reactive oxygen species (ROS) and lipid peroxidation product (LPOx) including acrolein and 4-hydroxynonenal (4HNE). The presence of these biochemical derangements results in neurodegeneration
Autor:
Anthony J. Convertine, T. Eoin West, Debobrato Das, Patrick S. Stayton, Taylor Monroe-Jones, Jasmin Chen, Brian Lee, Daniel M. Ratner, Hye Nam Son, Frank Radella, Shawn J. Skerrett, Dale Whittington, Fang-Yi Su, Selvi Srinivasan
Publikováno v:
Biomaterials. 195:38-50
Alveolar macrophages resident in the lung are prominent phagocytic effector cells of the pulmonary innate immune response, and paradoxically, are attractive harbors for pathogens. Consequently, facultative intracellular bacteria, such as Francisella
Autor:
Anthony J. Convertine, Jasmin Chen, Courtney Reichhardt, Fang-Yi Su, Shawn J. Skerrett, Daniel M. Ratner, Selvi Srinivasan, Daniel Passos da Silva, Debobrato Das, Elaine Limqueco, Patrick S. Stayton, Matthew R. Parsek
Publikováno v:
ACS Infect Dis
Biofilms are one of the most challenging obstacles in bacterial infections. By providing protection against immune responses and antibiotic therapies, biofilms enable chronic colonization and the development of antibiotic resistance. As previous clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48d959944e88d937fda75756f7d360d
https://europepmc.org/articles/PMC7769119/
https://europepmc.org/articles/PMC7769119/
Autor:
Shawn J. Skerrett, Selvi Srinivasan, Patrick S. Stayton, Anthony J. Convertine, Daniel M. Ratner, Brian Lee, Fang-Yi Su, Jasmin Chen, T.E. West
Publikováno v:
Journal of Controlled Release. 287:1-11
Intracellular bacterial infections localized to the lung alveolar macrophage (AM) remain one of the most challenging settings for antimicrobial therapy. Current systemic antibiotic treatment fails to deliver sustained doses to intracellular bacterial
Autor:
Justin M. Kollman, Daniel M. Ratner, Patrick S. Stayton, F. D. Brown, Selvi Srinivasan, Almar Postma, Debobrato Das, Fang-Yi Su, Anthony J. Convertine, Anika L. Burrell
Publikováno v:
Polymer Chemistry. 9:2134-2146
Radiant star nanoparticle (RSN) prodrugs were synthesized in a two-step process by first homopolymerizing RAFT transmers followed by copolymerization from the hyperbranched polymer core. Two trithiocarbonate-based transmers were synthesized containin
Publikováno v:
Polym Chem
Herein, we developed a fully polymerizable, peptide-targeted, camptothecin polymeric prodrug system. Two prodrug monomers were synthesized via esterification of campothecin (20Cam) and 10-hydroxycamptothecin (10Cam) with mono-2-(methacryloyloxy)ethyl
Autor:
Abby M. Kelly, Anthony J. Convertine, Patrick S. Stayton, T. Eoin West, Fang-Yi Su, Daniel M. Ratner, Jasmin Chen, Shawn J. Skerrett, Hye-Nam Son
Publikováno v:
Biomaterials Science. 6:1976-1985
Pulmonary intracellular infections, such as tuberculosis, anthrax, and tularemia, have remained a significant challenge to conventional antibiotic therapy. Ineffective antibiotic treatment of these infections can lead not only to undesired side effec
Autor:
Abby M. Kelly, Dasom Yoo, Alexander W. Magsam, Forrest M. Kievit, Anthony J. Convertine, Patrick S. Stayton
Publikováno v:
ACS Nano
Traumatic brain injury (TBI) is the leading cause of death and disability in children and young adults, yet there are currently no treatments available that prevent the secondary spread of damage beyond the initial insult. The chronic progression of
Autor:
Oliver W. Press, David M. Hockenbery, Patrick S. Stayton, Selvi Srinivasan, Hanna B. Kern, Anthony J. Convertine
Publikováno v:
Molecular Pharmaceutics. 14:1450-1459
Peptides derived from the third Bcl-2 homology domain (BH3) renormalize apoptotic signaling by antagonizing prosurvival Bcl-2 family members. These potential peptide drugs exhibit therapeutic activities but are limited by barriers including short cir