Výsledky vyhledávání - "Anthony J. Conley"

Vaccine Protection against a Heterologous, Non-Syncytium-Inducing, Primary Human Immunodeficiency Virus

Autor: Kamalpreet Arora, L. Jean Patterson, Marjorie Robert-Guroff, Harvinder Kaur, Phillip D. Markham, Michel Leno, Faruk Sinangil, Ersell Richardson, Philip M. McKenna, Lalita C. Murty, Anthony J. Conley, Lucretia Carter, Kristine Aldrich, Susan Zolla-Pazner

Publikováno v: Journal of Virology. 72:10275-10280

Vaccine-induced protection of chimpanzees against laboratory-adapted and syncytium-inducing, multiply passaged primary human immunodeficiency virus type 1 (HIV-1) isolates, but not against non-syncytium-inducing, minimally passaged ones, has been dem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee72d0a4fd9bcca94fdc2ceb8f8c5247
https://doi.org/10.1128/jvi.72.12.10275-10280.1998

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The consequence of passive administration of an anti-human immunodeficiency virus type 1 neutralizing monoclonal antibody before challenge of chimpanzees with a primary virus isolate

Autor: Joseph Kessler, S R Rouse, Emilio A. Emini, George E. Mark, Lynn J. Boots, Anthony J. Conley, William A. Schleif, Philip M. McKenna, K K Murthy, S M Lunceford, E K Cobb, Hermann Katinger

Publikováno v: Journal of Virology. 70:6751-6758

The anti-gp41 virus neutralizing monoclonal antibody 2F5 was infused into chimpanzees, which were then given an intravenous challenge with a primary human immunodeficiency virus type I (HIV-1) isolate. In two control animals, the infection was establ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46da3a441ac8a1baf4518e72c1fa673e
https://doi.org/10.1128/jvi.70.10.6751-6758.1996

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In VitroEffects of Anti-HIV Immunotoxins Directed against Multiple Epitopes on HIV Type 1 Envelope Glycoprotein 160

Autor: George K. Lewis, Seth H. Pincus, Robert L. Cole, Lee Eiden, Abraham Pinter, Abner Louis Notkins, Shermaine A. Tilley, Hua Fang, Vladimir Tolstikov, Jan McClure, David W. Dorward, Britta Wahren, Martin Teintze, Marshall R. Posner, Anthony J. Conley, Kathy Wehrly

Publikováno v: AIDS Research and Human Retroviruses. 12:1041-1051

We have used a panel of anti-gp160 MAbs to construct anti-HIV immunotoxins by coupling antibodies to ricin A chain (RAC). The ability of the immunotoxins to kill HIV-1-infected cells and halt the spread of infection was tested in tissue culture on pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a96fc3551a3e140d93ec6c5d2491e89
https://doi.org/10.1089/aid.1996.12.1041

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Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression

Autor: John R. Yannelli, Guiseppi Pantaleo, Yambasu A. Brewah, Steven A. Rosenberg, Simon Leath, Charles W. Carter, James F. Demarest, Christine Wannebo, Scott Koenig, Victoria J. Davey, Gary M. Jones, Lynn J. Boots, Anthony J. Conley, H. Clifford Lane

Publikováno v: Nature Medicine. 1:330-336

An HIV-1-seropositive volunteer was infused with an expanded autologous cytotoxic T lymphocyte (CTL) clone directed against the HIV-1 nef protein. This clone was adoptively transferred to determine whether supplementing CTL activity could reduce vira

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fdc0ccaec95adb99336a54a6fc3209
https://doi.org/10.1038/nm0495-330

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Neutralization of primary human immunodeficiency virus type 1 isolates by the broadly reactive anti-V3 monoclonal antibody, 447-52D

Autor: D W Lineberger, M Ossorio-Castro, S Koenig, M K Gorny, Joseph Kessler, Susan Zolla-Pazner, Lynn J. Boots, Anthony J. Conley, Emilio A. Emini, Constance Williams

Publikováno v: Journal of Virology. 68:6994-7000

Human monoclonal antibody 447-52D binds to the V3 determinant of the human immunodeficiency virus type 1 (HIV-1) gp120 external glycoprotein. Its binding requires the expression of the GPxR sequence at the center of the V3 domain. HIV-1 variants that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7991a072c09b7cf720548537bcb20068
https://doi.org/10.1128/jvi.68.11.6994-7000.1994

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Immunogenicity of synthetic HIV-1 gp120 V3-loop peptide-conjugate immunogens

Autor: Francis Van Middlesworth, Susan A. Warne, Patricia Conard, Meheryar N. Rivetna, Anthony J. Conley, Emilio A. Emini, Richard L. Tolman, John Hannah, Catherine A. Dolan, Steven S. Bondy, Jon A. Rudbach, Victoria K. Rusiecki, J. Terry Ulrich, Stephen Marburg, William J. Leanza, Elizabeth E. Sugg

Publikováno v: Vaccine. 12:445-451

A successful prophylactic human immunodeficiency virus type 1 (HIV-1) vaccine must elicit an immune response that will prevent establishment of the persistent viral infection. The only response shown to be effective in this regard is virus-neutralizi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958b2074439a5f0e1bb7ee5bd06f5c44
https://doi.org/10.1016/0264-410x(94)90123-6

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Complement-Mediated Enhancement of Antibody Function for Neutralization of Pseudotype Virus Containing Hepatitis C Virus E2 Chimeric Glycoprotein

Autor: L. Martin Lagging, Adrian M. Di Bisceglie, Ranjit Ray, Arnab Basu, Keith Meyer, Craig T. Przysiecki, Anthony J. Conley

We previously reported a number of features of hepatitis C virus (HCV) chimeric glycoproteins related to pseudotype virus entry into mammalian cells. In this study, pseudotype virus was neutralized by HCV E2 glycoprotein-specific antibodies and infec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74445fc1794144ea7575dc3e926f427c
https://europepmc.org/articles/PMC153822/

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Association of antibody reactivity to ELDKWA, a glycoprotein 41 neutralization epitope, with disease progression in children perinatally infected with HIV type 1

Autor: Shenghan Lai, Rebeca Geffin, Gwendolyn B. Scott, Philip M. McKenna, Cecelia Hutto, Michelle Melenwick, Lynn J. Boots, Anthony J. Conley, Joseph Kessler

Publikováno v: AIDS research and human retroviruses. 14(7)

The association between antibody reactivity to the neutralizing epitope ELDKWA in the transmembrane glycoprotein gp41 and disease progression was investigated in 29 children perinatally infected with HIV-1. Levels of antibody reactivity to this epito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebe33ae7a0c538f6cdaa4fe1d8aec9e
https://pubmed.ncbi.nlm.nih.gov/9591712

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Anti-human immunodeficiency virus type 1 human monoclonal antibodies that bind discontinuous epitopes in the viral glycoproteins can identify mimotopes from recombinant phage peptide display libraries

Autor: Philip M. McKenna, James E. Robinson, Paul M. Keller, Beth A. Arnold, Miroslaw K. Gorny, Lynn J. Boots, Anthony J. Conley, Susan Zolla-Pazner

Publikováno v: AIDS research and human retroviruses. 13(18)

A phage display library screening approach was used to identify peptide sequences that could bind to anti-HIV-1 MAbs whose binding specificities are complex. Most of the antibodies used recognize discontinuous epitopes in gp120 and one recognizes gp4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe10c4fde3e90e120368fffa81b237b
https://pubmed.ncbi.nlm.nih.gov/9430247

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