Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Anthony J. C. Leathem"'
Autor:
Aristotelis Antonopoulos, Stuart M. Haslam, Hannah J. Lomax-Browne, Miriam Dwek, Claire E. Robertson, Anthony J. C. Leathem, Anne Dell
The lectinHelix pomatiaagglutinin (HPA) recognizes altered glycosylation in solid cancers and the identification of HPA binding partners in tumour tissue and serum is an important aim. Among the many HPA binding proteins, IgA1 has been reported to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4e5b6b279cf2d5424eff1de6985b2d
https://europepmc.org/articles/PMC6388022/
https://europepmc.org/articles/PMC6388022/
Autor:
Marie M. Cantwell, Jayne V. Woodside, K. A. Perkins, Claire E. Robertson, Miriam Dwek, Susan J Dutton, Louiza S. Velentzis, Angela A. Mulligan, Anthony J. C. Leathem, Cristian Ciria, Ruth Swann
Publikováno v:
Maturitas. 75:232-240
DietCompLyf is a multi-centre prospective study designed to investigate associations between phytoestrogens - naturally occurring plant compounds with oestrogenic properties - and other diet and lifestyle factors with breast cancer recurrence and sur
Publikováno v:
Cancer Letters. 328:335-344
Aberrant glycosylation has long been recognised as a hallmark of cancer, and is increasingly being exploited in biomarker discovery studies. Helix pomatia agglutinin (HPA) is known to bind aberrant glycans associated with metastatic breast cancer, an
Autor:
Mohammed Keshtgar, Jayne V. Woodside, Louiza S. Velentzis, Anthony J. C. Leathem, Marie M. Cantwell
Publikováno v:
Velentzis, L S, Woodside, J, Cantwell, M, Leathem, A J & Keshtgar, M R 2008, ' Do phytoestrogens reduce the risk of breast cancer and breast cancer recurrence? What clinicians need to know. ' European journal of cancer (Oxford, England : 1990), vol 44, no. 13, pp. 1799-1806 . DOI: 10.1016/j.ejca.2008.05.019
Oestrogen is an important determinant of breast cancer risk. Oestrogen-mimicking plant compounds called phytoestrogens can bind to oestrogen receptors and exert weak oestrogenic effects. Despite this activity, epidemiological studies suggest that the
Publikováno v:
Journal of Chromatography B. 853:138-146
Phytoestrogens are currently the subject of intense study owing to their potential protective effects against a number of complex diseases. However, in order to investigate the interactions between phytoestrogens and disease state effectively, it is
Autor:
Raymond A. Dwek, Pauline M. Rudd, Mark R. Wormald, Simon A. Fry, Louise Royle, James M. McDonnell, Ghislain Opdenakker, Philippe E. Van den Steen, Anthony J. C. Leathem
Publikováno v:
Biochemistry. 45:15249-15258
Gelatinase B (MMP-9) and galectin-3 are widely known to participate in tumor cell invasion and metastasis. Glycans derived from MMP-9 expressed in MCF-7 breast cancer and THP-1 myeloid leukemia cells were compared with those from MMP-9 expressed in n
Publikováno v:
Nutrition Research. 26:7-10
The aim of this study was to determine how nutrient intake is affected by a short-term phytoestrogen-rich diet. Ten healthy volunteers consumed 100 g soya chunks, 150 g lentils, and 250 g kidney beans daily for 3 days. Urine was collected during the
Publikováno v:
European Journal of Clinical Nutrition. 58:173-179
Background: Isoflavones are estrogen-like plant compounds that may protect against cardiovascular disease and endocrine-responsive cancer. Isoflavones may, because of their ability to act as selective estrogen receptor modulators, alter insulin-like
Publikováno v:
PROTEOMICS. 1:756-762
Changes in glycosylation of glycoproteins and glycolipids is a common feature of cancer and may influence cancer cell behaviour, perhaps by enabling cell-cell interactions which favour metastasis or by allowing cancer cells to evade immuno-surveillan
Publikováno v:
Queen's University Belfast-PURE
Antioxidant species may act in vivo to decrease oxidative damage to DNA, protein and lipids thus reducing the risk of coronary heart disease and cancer. Phytoestrogens are plant compounds which are a major component of traditional Asian diets and whi