Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anthony J. Bonito"'
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 1, Pp 1980-2000 (2015)
Autoimmune hepatitis (AIH) is an immune-mediated disorder that affects the liver parenchyma. Diagnosis usually occurs at the later stages of the disease, complicating efforts towards understanding the causes of disease development. While animal model
Externí odkaz:
https://doaj.org/article/065dd591eac741dba902ce03cff3f86c
Autor:
Sayuri Yamazaki, Ryuta Uraki, Anthony J. Bonito, Maiko Watanabe, Kiyoshi Minohara, Makoto Tsuiji, Masaki Imai, Hiroaki Shime, Naganari Ohkura, Takuma Matoba, Hidehiro Fukuyama, Yoshiaki Yasumizu, Akimichi Morita, Mizuyu Odanaka, Shimon Sakaguchi
Publikováno v:
Proc Natl Acad Sci U S A
Foxp3+CD25+CD4+ regulatory T (Treg) cells constitute about 10% of peripheral CD4+ T cells and suppress a variety of immune responses in mice and humans (1). Our recent report (2) shows that proenkephalin (PENK)-expressing Treg cells expanded by ultra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf449d125b4864a3687a4e60b947c86a
https://europepmc.org/articles/PMC7826361/
https://europepmc.org/articles/PMC7826361/
Autor:
Anthony J. Bonito, Hidehiro Fukuyama, Naganari Ohkura, Ryuta Uraki, Yoshiaki Yasumizu, Maiko Watanabe, Shimon Sakaguchi, Takuma Matoba, Masaki Imai, Akimichi Morita, Mizuyu Odanaka, Makoto Tsuiji, Hiroaki Shime, Sayuri Yamazaki, Kiyoshi Minohara
Publikováno v:
Proc Natl Acad Sci U S A
Regulatory T (Treg) cells, expressing CD25 (interleukin-2 receptor α chain) and Foxp3 transcription factor, maintain immunological self-tolerance and suppress various immune responses. Here we report a feature of skin Treg cells expanded by ultravio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc18a079aad22817911b0fc82e11adaf
https://europepmc.org/articles/PMC7456133/
https://europepmc.org/articles/PMC7456133/
Autor:
Miriam Merad, Adeeb Rahman, Anthony J. Bonito, Konstantina Alexandropoulos, Seihwan Jeong, Huabao Xiong, Olivier Herbin, Erica G. Weinstein
Publikováno v:
Journal of Autoimmunity. 75:141-149
In the thymus, antigen presenting cells (APCs) namely, medullary thymic epithelial cells (mTECs) and thymic dendritic cells (tDCs) regulate T cell tolerance through elimination of autoreactive T cells and production of thymic T regulatory (tTreg) cel
Autor:
Olivier, Herbin, Anthony J, Bonito, Seihwan, Jeong, Erica G, Weinstein, Adeeb H, Rahman, Huabao, Xiong, Miriam, Merad, Konstantina, Alexandropoulos
Publikováno v:
Journal of autoimmunity. 75
In the thymus, antigen presenting cells (APCs) namely, medullary thymic epithelial cells (mTECs) and thymic dendritic cells (tDCs) regulate T cell tolerance through elimination of autoreactive T cells and production of thymic T regulatory (tTreg) cel
Autor:
Anthony J. Bonito, Gordon F. Heidkamp, Ralph M. Steinman, Sayuri Yamazaki, Michel C. Nussenzweig, Diana Dudziak, Christopher Fiorese, Kayo Inaba
Publikováno v:
The Journal of Immunology. 181:6923-6933
Foxp3(+)CD25(+)CD4(+) regulatory T cells (Treg) mediate immunological self-tolerance and suppress immune responses. A subset of dendritic cells (DCs) in the intestine is specialized to induce Treg in a TGF-beta- and retinoic acid-dependent manner to
Autor:
Miriam Merad, Emma L. Kuan, Gwendalyn J. Randolph, Milena Bogunovic, Anthony J. Bonito, Claudia Jakubzick
Publikováno v:
The Journal of Experimental Medicine
Observations that dendritic cells (DCs) constitutively enter afferent lymphatic vessels in many organs and that DCs in some tissues, such as the lung, turnover rapidly in the steady state have led to the concept that a major fraction of lymph node DC
Autor:
Sayuri Yamazaki, Anthony J. Bonito, Jae Y. Kim, Haekyung Lee, Sung Ho Park, Yoonkyung Do, Young-Sun Kang, Kayo Inaba, Ralph M. Steinman, Jae-Hoon Choi, Maggi Pack, Chae Gyu Park, Juliana Idoyaga, Cheolho Cheong
Publikováno v:
Journal of Immunological Methods. 324:48-62
Langerin CD207 is a type II transmembrane protein. It is responsible for the formation of Birbeck granules, which are intracellular organelles within Langerhans cells, the dendritic cells of stratified squamous epithelia like the epidermis. Because c
Autor:
Juliana Idoyaga, Anthony J. Bonito, Ralph M. Steinman, Shin-ichiro Fujii, Yang Liu, Xue-Feng Bai, Rosa Wainstok, José Mordoh, Kang Liu, Anna Charalambous
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
J. Exp. Med. 2005;202(11):1507-1516
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN
The Journal of Experimental Medicine
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
J. Exp. Med. 2005;202(11):1507-1516
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN
The Journal of Experimental Medicine
If irradiated tumor cells could be rendered immunogenic, they would provide a safe, broad, and patient-specific array of antigens for immunotherapies. Prior approaches have emphasized genetic transduction of live tumor cells to express cytokines, cos
Publikováno v:
The Journal of Experimental Medicine
Dendritic cell (DC) maturation is an innate response that leads to adaptive immunity to coadministered proteins. To begin to identify underlying mechanisms in intact lymphoid tissues, we studied alpha-galactosylceramide. This glycolipid activates inn