Zobrazeno 1 - 10 of 73 pro vyhledávání: '"Anthony J. Bakker"'
1
Akademický článek
Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb
Autor: Jenni M. Laitila, Elyshia L. McNamara, Catherine D. Wingate, Hayley Goullee, Jacob A. Ross, Rhonda L. Taylor, Robbert van der Pijl, Lisa M. Griffiths, Rachel Harries, Gianina Ravenscroft, Joshua S. Clayton, Caroline Sewry, Michael W. Lawlor, Coen A. C. Ottenheijm, Anthony J. Bakker, Julien Ochala, Nigel G. Laing, Carina Wallgren-Pettersson, Katarina Pelin, Kristen J. Nowak
Publikováno v: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Abstract Nemaline myopathy (NM) caused by mutations in the gene encoding nebulin (NEB) accounts for at least 50% of all NM cases worldwide, representing a significant disease burden. Most NEB-NM patients have autosomal recessive disease due to a comp
Externí odkaz: https://doaj.org/article/091348b090194a35b6fa183d1b10a74b
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3
Akademický článek
Lipopolysaccharide-induced weakness in the preterm diaphragm is associated with mitochondrial electron transport chain dysfunction and oxidative stress.
Autor: Yong Song, Gavin J Pinniger, Anthony J Bakker, Timothy J M Moss, Peter B Noble, Clare A Berry, Jane J Pillow
Publikováno v: PLoS ONE, Vol 8, Iss 9, p e73457 (2013)
Diaphragmatic contractility is reduced in preterm lambs after lipopolysaccharide (LPS) exposure in utero. The mechanism of impaired fetal diaphragm contractility after LPS exposure is unknown. We hypothesise that in utero exposure to LPS induces a de
Externí odkaz: https://doaj.org/article/498c212335304833b5b316ded8c0daef
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4
Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb
Autor: Michael W. Lawlor, Hayley Goullee, Rachel Harries, Coen A.C. Ottenheijm, Anthony J. Bakker, Julien Ochala, Robbert van der Pijl, Lisa M. Griffiths, Katarina Pelin, Gianina Ravenscroft, Kristen J. Nowak, Carina Wallgren-Pettersson, Elyshia McNamara, Caroline Sewry, Catherine D. Wingate, Rhonda L. Taylor, Joshua S. Clayton, Jacob A. Ross, Nigel G. Laing, J. Laitila
Publikováno v: Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Laitila, J M, McNamara, E L, Wingate, C D, Goullee, H, Ross, J A, Taylor, R L, van der Pijl, R, Griffiths, L M, Harries, R, Ravenscroft, G, Clayton, J S, Sewry, C, Lawlor, M W, Ottenheijm, C A C, Bakker, A J, Ochala, J, Laing, N G, Wallgren-Pettersson, C, Pelin, K & Nowak, K J 2020, ' Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb ', Acta neuropathologica communications, vol. 8, no. 1, 18 . https://doi.org/10.1186/s40478-020-0893-1
Acta neuropathologica communications, 8(1):18. BioMed Central
Nemaline myopathy (NM) caused by mutations in the gene encoding nebulin (NEB) accounts for at least 50% of all NM cases worldwide, representing a significant disease burden. Most NEB-NM patients have autosomal recessive disease due to a compound hete
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3f5c6a3537aab06d478ab85db00ac2
https://pubmed.ncbi.nlm.nih.gov/32066503
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5
Gestational age at time of in utero lipopolysaccharide exposure influences the severity of inflammation-induced diaphragm weakness in lambs
Autor: Peter B. Noble, Tanzila Mahzabin, J. Jane Pillow, Anthony J. Bakker, Gavin J. Pinniger, Yong Song, Kanakeswary Karisnan
Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 314:R523-R532
The preterm diaphragm is functionally immature compared with its term counterpart. In utero inflammation further exacerbates preterm diaphragm dysfunction. We hypothesized that preterm lambs are more vulnerable to in utero inflammation-induced diaphr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68467ded5936dc9b397a1cdf556e63a4
https://doi.org/10.1152/ajpregu.00150.2017
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6
Doublet stimulation increases Ca2+ binding to troponin C to ensure rapid force development in skeletal muscle
Autor: Catherine D. Wingate, Christopher John Barclay, Bradley S. Launikonis, Tanya R. Cully, Anthony J. Bakker
Publikováno v: Journal of General Physiology. 149:323-334
Fast-twitch skeletal muscle fibers are often exposed to motor neuron double discharges (≥200 Hz), which markedly increase both the rate of contraction and the magnitude of the resulting force responses. However, the mechanism responsible for these
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9e3a33b1f228116e2ff860d2aea9912
https://doi.org/10.1085/jgp.201611727
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7
Gestational age at initial exposure toin uteroinflammation influences the extent of diaphragm dysfunction in preterm lambs
Autor: Yong Song, Gavin J. Pinniger, Kanakeswary Karisnan, Peter B. Noble, Anthony J. Bakker, J. Jane Pillow
Publikováno v: Respirology. 20:1255-1262
Background and objective In utero infection may critically influence diaphragm development and predispose preterm infants to postnatal respiratory failure. We aimed to determine how frequency and gestational age (GA) at time of intra-amniotic (IA) li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8853831847af638160bab4e937525a39
https://doi.org/10.1111/resp.12615
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8
Hierarchical Patterning of Multifunctional Conducting Polymer Nanoparticles as a Bionic Platform for Topographic Contact Guidance
Autor: Stuart I. Hodgetts, Alaa M. Munshi, Igor Luzinov, Giles W. Plant, Jianli Zou, Alan R. Harvey, K. Swaminathan Iyer, Dominic Ho, Anthony J. Bakker, Vipul Agarwal, Nicole M. Smith, Xianjue Chen
Publikováno v: ACS Nano. 9:1767-1774
The use of programmed electrical signals to influence biological events has been a widely accepted clinical methodology for neurostimulation. An optimal biocompatible platform for neural activation efficiently transfers electrical signals across the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6490cf8abc8b8737f2c67d4072da33ac
https://doi.org/10.1021/nn506607x
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9
Contractile properties of slow and fast skeletal muscles from protease activated receptor-1 null mice
Autor: H.-J. Yoo, Charles N. Pagel, Eleanor J. Mackie, Gavin J. Pinniger, Anthony J. Bakker, Paran K. Sitparan
Publikováno v: Muscle & Nerve. 50:991-998
Introduction: Protease-activated receptors (PARs) may play a role in skeletal muscle development. We compared the contractile properties of slow-twitch soleus muscles and fast-twitch extensor digitorum longus (EDL) muscles from PAR-1 null and litterm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e985504389ef83a1fe225fe6f2e0149
https://doi.org/10.1002/mus.24256
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10
The beneficial effect of Icaritin on osteoporotic bone is dependent on the treatment initiation timing in adult ovariectomized rats
Autor: Yixin He, Leung-Kim Hung, Bao-Ting Zhang, Wanxin Zhen, Ling Qin, Songlin Peng, Anthony J. Bakker, Xiaohua Pan, Wing Nang Leung, Baosheng Guo, Ge Zhang
Publikováno v: Bone. 55:230-240
Background Epimedium-derived flavonoids (EFs) have a potential to treat established osteoporosis in postmenopausal women. However, one of the main disadvantages of the compound is the high volume and dosage during long-term administration period. Mea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ecdaf6f12cbb8ffe9c0641c329e7b5
https://doi.org/10.1016/j.bone.2013.02.012
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