Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anthony J. Apostoli"'
Publikováno v:
PPAR Research, Vol 2012 (2012)
ATP-dependent binding cassette (ABC) transporters are a family of transmembrane proteins that pump a variety of hydrophobic compounds across cellular and subcellular barriers and are implicated in human diseases such as cancer and atherosclerosis. In
Externí odkaz:
https://doaj.org/article/560acbde3a9241dea369e6cd9c192b59
Autor:
Joseph Paul Walton, Jalna Meens, Cheryl H. Arrowsmith, Julia Dmytryshyn, Laurie Ailles, Anthony J. Apostoli
Publikováno v:
Cancer Research. 80:1766-1766
Sporadic Renal Cell Carcinoma (RCC) is dominated by the clear cell subtype (ccRCC) and overwhelmingly associated with a biallelic inactivation of the von Hippel-Lindau (VHL) gene, leading to constitutive activation of the hypoxia response and deleter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17441ccb0b5bbd81798e31a79af5233e
https://doi.org/10.1158/1538-7445.am2020-1766
https://doi.org/10.1158/1538-7445.am2020-1766
Autor:
Laurie Ailles, Anthony J. Apostoli
Publikováno v:
Critical Reviews in Clinical Laboratory Sciences. 53:40-51
Human cancer is not a uniform disease but a plethora of disparate tumor types and subtypes. The differences that exist between individual tumors (intertumoral heterogeneity) present a significant roadblock to the eradication of cancer. It has also be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c44d00cba981d009cbe6aec5cc28a94
https://doi.org/10.3109/10408363.2015.1083944
https://doi.org/10.3109/10408363.2015.1083944
Autor:
Michael Di Lena, Graham Skelhorne-Gross, Sandip SenGupta, Rachel E. Rubino, Anthony J. Apostoli, Christopher J. Nicol, Nichole Peterson, Mark M. Schneider
Publikováno v:
International Journal of Cancer. Journal International du Cancer
Breast cancer is the leading cause of new cancer diagnoses among women. Using peroxisome proliferator-activated receptor (PPAR)γ((+/-)) mice, we showed normal expression of PPARγ was critical to stop 7,12-dimethylbenz[a]anthracene (DMBA)-induced br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ca867e069b34cfce8f4552225867c4
http://europepmc.org/articles/PMC4233966
http://europepmc.org/articles/PMC4233966
Autor:
Andrew Evans, Laurie Ailles, Nazleen Lobo, Girish S. Kulkarni, Jason Moffat, Anthony J. Apostoli, Craig Gedye, Michael Robinette, Joshua Paterson, Antonio Finelli, Natalie Stickle, Kevin R. Brown, Neil Fleshner, Michael A.S. Jewett, Alexandre R. Zlotta, Robert J. Hamilton
Publikováno v:
BMC Cancer
Background Patients with clear cell renal cell carcinoma (ccRCC) have few therapeutic options, as ccRCC is unresponsive to chemotherapy and is highly resistant to radiation. Recently targeted therapies have extended progression-free survival, but res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f4f68b9c50abe841bedb04e41d6a1c
https://doi.org/10.1186/s12885-016-2539-z
https://doi.org/10.1186/s12885-016-2539-z
Autor:
Elizabeth Lightbody, Kevin Ren, Anthony J. Apostoli, Christopher J. Nicol, Kathleen Mj O'Connell, Rachel R. Rubino, Sandip SenGupta, Hailey T. Newton
Publikováno v:
Cancer Research. 78:110-110
Breast tumors that overexpress human epidermal growth factor receptor 2 (HER2+) grow and spread faster than HER2-negative tumors, resulting in poor patient prognosis. Peroxisome proliferator-activated receptor (PPAR)γ is a nuclear transcription fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f94861362125b8974fa36ea10d6ac149
https://doi.org/10.1158/1538-7445.am2018-110
https://doi.org/10.1158/1538-7445.am2018-110
Autor:
Anthony J. Apostoli, Dalia Barsyte-Lovejoy, Laurie Ailles, Nazleen Lobo, Cheryl Arrow Smith, Panagiotis Prinos
Publikováno v:
Cancer Research. 76:1240-1240
Clear cell renal cell carcinoma (ccRCC), the most common subtype of renal cell cancer, is highly resistant to traditional radiation and chemotherapy. Recently, targeted therapies have extended progression-free survival, but responses are variable and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fc4c8b912335f062f20ba5a3fb2738f
https://doi.org/10.1158/1538-7445.am2016-1240
https://doi.org/10.1158/1538-7445.am2016-1240
Autor:
Christopher J. Nicol, Rachel E. Rubino, Alexis L Reid, Graham Skelhorne-Gross, Anthony J. Apostoli, Mark M. Schneider, Michael Di Lena, Sandip SenGupta, Frank J. Gonzalez, Nichole Peterson
Publikováno v:
Carcinogenesis. 33(7)
Peroxisome proliferator-activated receptor (PPAR)γ regulates the expression of genes essential for fat storage, primarily through its activity in adipocytes. It also has a role in carcinogenesis. PPARγ normally stops the in vivo progression of 7,12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36429cbdefb920274079771766570c6
https://pubmed.ncbi.nlm.nih.gov/22581835
https://pubmed.ncbi.nlm.nih.gov/22581835
Autor:
Anthony J. Apostoli
Publikováno v:
Health Science Inquiry. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3735e0249d67cbf5832849063db5d7e
https://doi.org/10.29173/hsi49
https://doi.org/10.29173/hsi49
Autor:
Mark M. Schneider, Nichole Peterson, Sandip SenGupta, Jennifer M Roche, Rachel E. Rubino, Christopher J. Nicol, Anthony J. Apostoli, Michael Di Lena
Publikováno v:
Molecular Cancer
Background Among women worldwide, breast cancer is the most commonly diagnosed cancer, and the second leading cause of cancer-related deaths. Improved understanding of breast tumourigenesis may facilitate the development of more effective therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f970d8b1cf81f47060777458758edd