Zobrazeno 1 - 10
of 500
pro vyhledávání: '"Anthony J Schaeffer"'
Autor:
Afrida Rahman-Enyart, Ryan E Yaggie, Justin L Bollinger, Constadina Arvanitis, Deborah R Winter, Anthony J Schaeffer, David J Klumpp
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0269140 (2022)
Chronic pelvic pain conditions such as interstitial cystitis/bladder pain syndrome (IC/BPS) remain clinical and mechanistic enigmas. Microglia are resident immune cells of the central nervous system (CNS) that respond to changes in the gut microbiome
Externí odkaz:
https://doaj.org/article/b798923e975d4b64b7385bedc6ffb384
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0235384 (2020)
Interstitial cystitis/bladder pain syndrome (IC) is a debilitating condition of chronic pelvic pain with unknown etiology. Recently, we used a genetic approach in a murine model of IC to identify the lipase acyloxyacyl hydrolase (AOAH) as a modulator
Externí odkaz:
https://doaj.org/article/16e4039d3de04b969a581ae141e39016
Autor:
Gilad Segev, Hilla Chen, Jonathan D. Dear, Beatriz Martínez López, Jully Pires, David J. Klumpp, Anthony J. Schaeffer, Jodi L. Westropp
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 5, Pp 2548-2555 (2024)
Abstract Background Recurrent bacterial cystitis, often referred to as recurrent urinary tract infection (UTI), can be difficult to manage and alternative treatments are needed. Hypothesis/Objective Intravesicular administration of asymptomatic bacte
Externí odkaz:
https://doaj.org/article/854b1ab19cca48a3a38b9e3c529abb76
Autor:
Matthew S. Swallow, Cynthia A. Sharadin, Anthony J. Schaeffer, Deborah L. Jacobson, Glen A. Lau
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
ObjectivesTo investigate the clinical presentation and outcomes for a series of female pediatric patients with severe anterior deflection of the urinary stream (ADUS) who were managed via urethromeatoplasty.MethodsThis single institution retrospectiv
Externí odkaz:
https://doaj.org/article/1215c7a78f0c4918b49d3858f26773aa
Autor:
Stephen F Murphy, Anthony J Schaeffer, Joseph Done, Larry Wong, Ashlee Bell-Cohn, Kenny Roman, John Cashy, Michelle Ohlhausen, Praveen Thumbikat
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125623 (2015)
Chronic pelvic pain syndrome (CPPS) is the most common form of prostatitis, accounting for 90-95% of all diagnoses. It is a complex multi-symptom syndrome with unknown etiology and limited effective treatments. Previous investigations highlight roles
Externí odkaz:
https://doaj.org/article/278af18aca614098b381e3d21d2c34e7
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e109321 (2014)
Urinary tract infections (UTI) account for approximately 8 million clinic visits annually with symptoms that include acute pelvic pain, dysuria, and irritative voiding. Empiric UTI management with antimicrobials is complicated by increasing antimicro
Externí odkaz:
https://doaj.org/article/d23d215621d44c45b0584add19276b21
Autor:
Marsha L Quick, Larry Wong, Soumi Mukherjee, Joseph D Done, Anthony J Schaeffer, Praveen Thumbikat
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60987 (2013)
The etiology of chronic prostatitis/chronic pelvic pain syndrome in men is unknown but may involve microbes and autoimmune mechanisms. We developed an infection model of chronic pelvic pain in NOD/ShiLtJ (NOD) mice with a clinical Escherichia coli is
Externí odkaz:
https://doaj.org/article/d2e8912b1870449f96871b7d2e252f0c
Autor:
Charles N Rudick, Mingchen Jiang, Ryan E Yaggie, Vladimir I Pavlov, Joseph Done, Charles J Heckman, Christopher Whitfield, Anthony J Schaeffer, David J Klumpp
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e41273 (2012)
The molecular initiators of infection-associated pain are not understood. We recently found that uropathogenic E. coli (UPEC) elicited acute pelvic pain in murine urinary tract infection (UTI). UTI pain was due to E. coli lipopolysaccharide (LPS) and
Externí odkaz:
https://doaj.org/article/733fa6ea0e3248a680150049c11b557b
Autor:
Praveen Thumbikat, Ruth E Berry, Ge Zhou, Benjamin K Billips, Ryan E Yaggie, Tetiana Zaichuk, Tung-Tien Sun, Anthony J Schaeffer, David J Klumpp
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000415 (2009)
Urinary tract infections are the second most common infectious disease in humans and are predominantly caused by uropathogenic E. coli (UPEC). A majority of UPEC isolates express the type 1 pilus adhesin, FimH, and cell culture and murine studies dem
Externí odkaz:
https://doaj.org/article/be99d1795d0047bfb61aa5736bbf47ca
Autor:
Angelo M. De Marzo, William G. Nelson, Edward M. Schaeffer, Anthony J. Schaeffer, Brian W. Simons, Shu-Han Yu, Heidi Hempel, Kirstie Canene-Adams, Karen S. Sfanos
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db6531acf07056bebb6e8eb5a45a27b
https://doi.org/10.1158/1940-6207.22526940
https://doi.org/10.1158/1940-6207.22526940