Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Anthony J A, Molina"'
Autor:
Jeanne F Nichols, Ryan Moran, Howard J Phang, Stephanie R Heimler, Lina M Scandalis, David Wing, Daniel Moreno, Gerald S Shadel, Fred H Gage, Anthony J A Molina
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Introduction While it is well recognised that aging is a heterogeneous process, our understanding of the determinants of biological aging and its heterogeneity remains unclear. The San Diego Nathan Shock Center (SD-NSC) Clinical Cohort aims to establ
Externí odkaz:
https://doaj.org/article/7d8cd9a0abba4c6285340ff8ff1a52db
Autor:
K. Allison Amick, Gargi Mahapatra, Zhengrong Gao, Amber Dewitt, Suzanne Craft, Mohit Jain, Anthony J. A. Molina
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Mitochondrial bioenergetic alterations occur in the brain and peripheral cells of patients with Alzheimer’s disease (AD). This study focuses on plasma circulating factors, namely lipids, as mediators of systemic bioenergetic differences in particip
Externí odkaz:
https://doaj.org/article/f6c1b8ffd3af4024b5b68fa492e0d894
Autor:
Lina Scandalis, Dalane W. Kitzman, Barbara J. Nicklas, Mary Lyles, Peter Brubaker, M. Benjamin Nelson, Michelle Gordon, John Stone, Jaclyn Bergstrom, P. Darrell Neufer, Erich Gnaiger, Anthony J. A. Molina
Publikováno v:
JAMA Cardiology.
ImportanceThe pathophysiology of exercise intolerance in patients with heart failure with preserved ejection fraction (HFpEF) remains incompletely understood. Multiple lines of evidence suggest that abnormal skeletal muscle metabolism is a key contri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54d247bb464772d45b581a271a984a7f
https://doi.org/10.1001/jamacardio.2023.0957
https://doi.org/10.1001/jamacardio.2023.0957
Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl‐CoA
Autor:
Jennifer Ngo, Dong Wook Choi, Illana A Stanley, Linsey Stiles, Anthony J A Molina, Pei‐Hsuan Chen, Ana Lako, Isabelle Chiao Han Sung, Rishov Goswami, Min‐young Kim, Nathanael Miller, Siyouneh Baghdasarian, Doyeon Kim‐Vasquez, Anthony E Jones, Brett Roach, Vincent Gutierrez, Karel Erion, Ajit S Divakaruni, Marc Liesa, Nika N Danial, Orian S Shirihai
Publikováno v:
The EMBO Journal. 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::017e8557c3a2be64d46de431d471a56b
https://doi.org/10.15252/embj.2022111901
https://doi.org/10.15252/embj.2022111901
Autor:
Theresa Mau, Li-Yung Lui, Giovanna Distefano, Philip A Kramer, Sofhia V Ramos, Frederico G S Toledo, Adam J Santanasto, Eric G Shankland, David J Marcinek, Michael J Jurczak, Ian Sipula, Fiona M Bello, Kate A Duchowny, Anthony J A Molina, Lauren M Sparks, Bret H Goodpaster, Russell T Hepple, Stephen B Kritchevsky, Anne B Newman, Peggy M Cawthon, Steven R Cummings, Paul M Coen
Publikováno v:
The Journals of Gerontology: Series A.
BackgroundMitochondrial energetics are an important property of aging muscle, as generation of energy is pivotal to the execution of muscle contraction. However, its association with functional outcomes, including leg power and cardiorespiratory fitn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc09dfefb0fd6243f6a07752cb0ab69e
https://doi.org/10.1093/gerona/glac238
https://doi.org/10.1093/gerona/glac238
Autor:
Peter H. Brubaker, Barbara J. Nicklas, Denise K. Houston, W. Gregory Hundley, Haiying Chen, M. Anthony J. A. Molina, W. Mary Lyles, Benjamin Nelson, Bharathi Upadhya, Russell Newland, Dalane W. Kitzman
Publikováno v:
Circulation. Heart failure.
Background: We've shown that combined caloric restriction (CR) and aerobic exercise training (AT) improve peak exercise O 2 consumption (VO 2 peak); and quality-of-life (QOL) in older patients with obese heart failure with preserved ejection fraction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592b7fdda7b17b4ae121e800d2cbafca
https://pubmed.ncbi.nlm.nih.gov/36314122
https://pubmed.ncbi.nlm.nih.gov/36314122
Autor:
Gargi Mahapatra, Zhengrong Gao, James R. Bateman, Samuel Neal Lockhart, Jaclyn Bergstrom, Amber Renee DeWitt, Jemima Elizabeth Piloso, Philip Adam Kramer, Jenny L. Gonzalez‐Armenta, Kimberly Allison Amick, Ramon Casanova, Suzanne Craft, Anthony J. A. Molina
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES.
Despite evidence for systemic mitochondrial dysfunction early in Alzheimer's disease (AD) pathogenesis, reliable approaches monitoring these key bioenergetic alterations are lacking. We used peripheral blood mononuclear cells (PBMCs) and platelets as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51758000c7f4ec5261797b7648d1aedf
https://pubmed.ncbi.nlm.nih.gov/35870133
https://pubmed.ncbi.nlm.nih.gov/35870133
Autor:
Alex Junker, Jennifer Wang, Gilles Gouspillou, Johannes K. Ehinger, Eskil Elmér, Fredrik Sjövall, Kelsey H. Fisher‐Wellman, P. Darrell Neufer, Anthony J. A. Molina, Luigi Ferrucci, Martin Picard
Publikováno v:
FASEB J
Mitochondria are maternally inherited organelles that play critical tissue-specific roles, including hormone synthesis and energy production, that influence human development, health, and aging. However, whether mitochondria from women and men exhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0620d23cff3d2e4cd4099924db56a964
https://pubmed.ncbi.nlm.nih.gov/35073429
https://pubmed.ncbi.nlm.nih.gov/35073429
Autor:
DengFeng, Li, James A, Snipes, Mariana, Murea, Anthony J A, Molina, Jasmin, Divers, Barry I, Freedman, Lijun, Ma, Snezana, Petrovic
Publikováno v:
Am J Nephrol
Apolipoprotein L1 gene (APOL1) G1 and G2 kidney-risk variants (KRVs) cause CKD in African Americans, inducing mitochondrial dysfunction. Modifying factors are required, because a minority of individuals with APOL1 high-risk genotypes develop nephropa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6fab38ebe9d981827bee82bcadf51d7e
https://pubmed.ncbi.nlm.nih.gov/32882695
https://pubmed.ncbi.nlm.nih.gov/32882695
Autor:
Kylie, Kavanagh, Ashley T, Davis, Diane E, Peters, Andre C, LeGrand, Manish S, Bharadwaj, Anthony J A, Molina
Publikováno v:
Obesity (Silver Spring, Md.). 25(4)
Obesity exists with and without accompanying cardiometabolic disease, termed metabolically unhealthy obesity (MUO) and healthy obesity (MHO), respectively. Underlying differences in the ability of subcutaneous (SQ) fat to respond to nutrient excess a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ff01c1a9057d3e25daeee8121f90210
https://pubmed.ncbi.nlm.nih.gov/28349666
https://pubmed.ncbi.nlm.nih.gov/28349666