Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Anthony J, Murgo"'
Autor:
Seth M. Steinberg, Anthony J. Murgo, William D. Figg, Vitaliy Pishchik, G. Aaron Chen, Julie A. Hong, Ana Hancox, Tricia F. Kunst, Xinmin Li, Ming Zhao, Dao M. Nguyen, Maria R. Fischette, David S. Schrump
Supplementary Figure 1 from Phase I Study of Decitabine-Mediated Gene Expression in Patients with Cancers Involving the Lungs, Esophagus, or Pleura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9f335f1e214fae11ec131f72ab38a9
https://doi.org/10.1158/1078-0432.22441464
https://doi.org/10.1158/1078-0432.22441464
Autor:
Seth M. Steinberg, Anthony J. Murgo, William D. Figg, Vitaliy Pishchik, G. Aaron Chen, Julie A. Hong, Ana Hancox, Tricia F. Kunst, Xinmin Li, Ming Zhao, Dao M. Nguyen, Maria R. Fischette, David S. Schrump
Purpose: The DNA methylation paradox, manifested as derepression of cancer-testis antigens, and silencing of tumor suppressors during malignant transformation, provides the rationale for the utilization of chromatin remodeling agents for cancer thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882f9fc79a7ff61fe6b4d2aa8704df79
https://doi.org/10.1158/1078-0432.c.6518526.v1
https://doi.org/10.1158/1078-0432.c.6518526.v1
Autor:
Robert J. Kinders, James H. Doroshow, Joseph E. Tomaszewski, Anthony J. Murgo, Martin E. Gutierrez, Yvonne A. Evrard, Larry Rubinstein, Shivaani Kummar, Ralph E. Parchment, Thomas D. Pfister, Lihua H. Wang
Purpose: Circulating tumor cells (CTC) in peripheral blood of patients potentially represent a fraction of solid tumor cells available for more frequent pharmacodynamic assessment of drug action than is possible using tumor biopsy. However, currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60a236e106e8634cb694f012d26d42f
https://doi.org/10.1158/1078-0432.c.6519651
https://doi.org/10.1158/1078-0432.c.6519651
Autor:
Giovanni Melillo, James H. Doroshow, Anthony J. Murgo, Peter Choyke, Ismail Baris Turkbey, Xiaohong Chen, William D. Figg, Shawn D. Spencer, Annamaria Rapisarda, Seth M. Steinberg, Deborah Allen, Agnes Strassberger, Yvonne Horneffer, Lamin Juwara, Mark Raffeld, Shivaani Kummar
PDF file - 56K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ed6d161ad3684caab88a8d6c71a270
https://doi.org/10.1158/1078-0432.22443482
https://doi.org/10.1158/1078-0432.22443482
Autor:
Giovanni Melillo, James H. Doroshow, Anthony J. Murgo, Peter Choyke, Ismail Baris Turkbey, Xiaohong Chen, William D. Figg, Shawn D. Spencer, Annamaria Rapisarda, Seth M. Steinberg, Deborah Allen, Agnes Strassberger, Yvonne Horneffer, Lamin Juwara, Mark Raffeld, Shivaani Kummar
Purpose: Hypoxia-inducible factor 1 (HIF-1) α is frequently overexpressed in human tumors and is associated with angiogenesis and metastasis. Topotecan, a topoisomerase I inhibitor, has been shown to inhibit HIF-1α expression in preclinical models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009a708f5cad832d1e35d7b8d4352d71
https://doi.org/10.1158/1078-0432.c.6519830.v1
https://doi.org/10.1158/1078-0432.c.6519830.v1
Autor:
Seth M. Steinberg, Anthony J. Murgo, William D. Figg, Vitaliy Pishchik, G. Aaron Chen, Julie A. Hong, Ana Hancox, Tricia F. Kunst, Xinmin Li, Ming Zhao, Dao M. Nguyen, Maria R. Fischette, David S. Schrump
Supplementary Table 1 from Phase I Study of Decitabine-Mediated Gene Expression in Patients with Cancers Involving the Lungs, Esophagus, or Pleura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056e62cb7b06f5ff10351900587f6b17
https://doi.org/10.1158/1078-0432.22441461.v1
https://doi.org/10.1158/1078-0432.22441461.v1
Autor:
James H. Doroshow, Joseph E. Tomaszewski, William Bonner, Yves Pommier, Giovanni Melillo, Melinda Hollingshead, Larry Rubinstein, Howard Stotler, John Carter, Ralph E. Parchment, Lihua Wang, Robert Kinders, Anthony J. Murgo, Giovanna Speranza, Marcie Weil, Lee Jia, Matthew Ames, Joel M. Reid, Yiping Zhang, Jiuping Ji, Alice Chen, Shivaani Kummar
PDF file - 102K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b77f467a1a5acacb480f930156b3df
https://doi.org/10.1158/0008-5472.22390272
https://doi.org/10.1158/0008-5472.22390272
Autor:
James H. Doroshow, Joseph E. Tomaszewski, William Bonner, Yves Pommier, Giovanni Melillo, Melinda Hollingshead, Larry Rubinstein, Howard Stotler, John Carter, Ralph E. Parchment, Lihua Wang, Robert Kinders, Anthony J. Murgo, Giovanna Speranza, Marcie Weil, Lee Jia, Matthew Ames, Joel M. Reid, Yiping Zhang, Jiuping Ji, Alice Chen, Shivaani Kummar
A phase I trial of ABT-888 (veliparib), a PARP inhibitor, in combination with topotecan, a topoisomerase I–targeted agent, was carried out to determine maximum tolerated dose (MTD), safety, pharmacokinetics, and pharmacodynamics of the combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3d4608740b7707dcaaae40455b961cc
https://doi.org/10.1158/0008-5472.c.6502884.v1
https://doi.org/10.1158/0008-5472.c.6502884.v1
Publikováno v:
Stress, Immunity, and Aging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339a570c20ec850cae3cc061dc6c5007
https://doi.org/10.4324/9781003065180-23
https://doi.org/10.4324/9781003065180-23
Autor:
Richard Pazdur, Yang-Min Ning, Anthony J. Murgo, Christine Merenda, Jonca Bull, Paul G. Kluetz, Michel D. Wissing
Publikováno v:
Cancer. 120:3025-3032
BACKGROUND US Food and Drug Administration (FDA) approval of new drugs depends on results from clinical trials that must be generalized to the US population. However, racial minorities are frequently under-represented in clinical studies. The enrollm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f43292c4d91fab35dcc1ab196c8e0a
https://doi.org/10.1002/cncr.28809
https://doi.org/10.1002/cncr.28809
