Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Anthony J, Mirando"'
Autor:
Jason T Long, Abigail Leinroth, Yihan Liao, Yinshi Ren, Anthony J Mirando, Tuyet Nguyen, Wendi Guo, Deepika Sharma, Douglas Rouse, Colleen Wu, Kathryn Song Eng Cheah, Courtney M Karner, Matthew J Hilton
Publikováno v:
eLife, Vol 11 (2022)
Hypertrophic chondrocytes give rise to osteoblasts during skeletal development; however, the process by which these non-mitotic cells make this transition is not well understood. Prior studies have also suggested that skeletal stem and progenitor cel
Externí odkaz:
https://doaj.org/article/e5000bdddb6c48f5925edceea43da35c
HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly.
Autor:
Deepika Sharma, Anthony J Mirando, Abigail Leinroth, Jason T Long, Courtney M Karner, Matthew J Hilton
Publikováno v:
PLoS Genetics, Vol 17, Iss 12, p e1009982 (2021)
Sonic Hedgehog/GLI3 signaling is critical in regulating digit number, such that Gli3-deficiency results in polydactyly and Shh-deficiency leads to digit number reductions. SHH/GLI3 signaling regulates cell cycle factors controlling mesenchymal cell p
Externí odkaz:
https://doaj.org/article/c0ddf0fe38a04ddc84c2ce80fbc65e0e
Autor:
Yihan Liao, Yinshi Ren, Xin Luo, Anthony J. Mirando, Jason T. Long, Abigail Leinroth, Ru-Rong Ji, Matthew J. Hilton
Publikováno v:
Sci Signal
Osteoarthritis (OA) and posttraumatic OA (PTOA) are caused by an imbalance in catabolic and anabolic processes in articular cartilage and proinflammatory changes throughout the joint, leading to joint degeneration and pain. We examined whether interl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59318f073c77e92207b3bed39da95209
https://doi.org/10.1126/scisignal.abn7082
https://doi.org/10.1126/scisignal.abn7082
Autor:
Sangsu Bang, Anthony J. Mirando, Christopher R. Donnelly, Xueshu Tao, Yihan Liao, Ouyang Chen, Matthew J. Hilton, Kaiyuan Wang, Yun Gu, Ru-Rong Ji
Publikováno v:
J Clin Invest
Emerging immune therapy, such as with the anti–programmed cell death–1 (anti–PD-1) monoclonal antibody nivolumab, has shown efficacy in tumor suppression. Patients with terminal cancer suffer from cancer pain as a result of bone metastasis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888c1cd74f345502eba5a23cece181b9
https://doi.org/10.1172/jci133334
https://doi.org/10.1172/jci133334
Autor:
Abigail Leinroth, Jason T. Long, Yinshi Ren, Yihan Liao, Matthew J. Hilton, Anthony J. Mirando, Ru-Rong Ji, Xin Luo
Osteoarthritis (OA) and post-traumatic OA (PTOA) are prevalent joint disorders and leading causes of chronic pain. The disease pathology of OA/PTOA is caused by imbalanced catabolic and anabolic responses and pro-inflammatory changes; however, their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cde1748942496c2c9b05f8a429271de9
https://doi.org/10.1101/2021.09.08.459303
https://doi.org/10.1101/2021.09.08.459303
Publikováno v:
Magn Reson Med
PURPOSE: To evaluate the complex fiber orientations and three-dimensional collagen fiber network of knee joint connective tissues, including ligaments, muscle, articular cartilage, and meniscus using high spatial and angular resolution diffusion imag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f273dbe117900a6b9d8a2e5250ecffe2
https://doi.org/10.1002/mrm.28181
https://doi.org/10.1002/mrm.28181
Autor:
Jiang Fu, H-M Ivy Yu, Shang-Yi Chiu, Anthony J Mirando, Eri O Maruyama, Jr-Gang Cheng, Wei Hsu
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004579 (2014)
Post-translational modification of proteins by small ubiquitin-related modifier (SUMO) is reversible and highly evolutionarily conserved from yeasts to humans. Unlike ubiquitination with a well-established role in protein degradation, sumoylation may
Externí odkaz:
https://doaj.org/article/8b76b96e85174849bdc1aa12700ee15b
Autor:
Jason T. Long, Abigail Leinroth, Yihan Liao, Yinshi Ren, Anthony J. Mirando, Tuyet Nguyen, Wendi Guo, Deepika Sharma, Douglas Rouse, Colleen Wu, Kathryn Song Eng Cheah, Courtney M. Karner, Matthew J. Hilton
Hypertrophic chondrocytes give rise to osteoblasts during skeletal development; however, the process by which these non-mitotic cells make this transition is not well understood. Prior studies have also suggested that skeletal stem and progenitor cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9596c484d94f9518a2a54f3c32e8a497
https://doi.org/10.1101/2021.05.18.444731
https://doi.org/10.1101/2021.05.18.444731
Autor:
Ken Gall, Helena Barber, Bijan Abar, Cambre N. Kelly, Anh Le-Tuan Pham, Matthew J. Hilton, Samuel B. Adams, Anthony J. Mirando, Alexander Kelly, Nicholas B. Allen
Publikováno v:
J Biomed Mater Res A
Critical-sized defects remain a significant challenge in orthopaedics. 3D printed scaffolds are a promising treatment but are still limited due to inconsistent osseous integration. The goal of the study is to understand how changing the surface rough
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3332335b5dc32289ad260b46d025448
https://pubmed.ncbi.nlm.nih.gov/33754494
https://pubmed.ncbi.nlm.nih.gov/33754494
Autor:
Abigail P. Leinroth, Anthony J. Mirando, Douglas Rouse, Yoshihiko Kobayahsi, Purushothama Rao Tata, Helen E. Rueckert, Yihan Liao, Jason T. Long, Joe V. Chakkalakal, Matthew J. Hilton
Publikováno v:
Cell Reports. 39:110785
Mesenchymal progenitors of the lateral plate mesoderm give rise to various cell fates within limbs, including a heterogeneous group of muscle-resident mesenchymal cells. Often described as fibro-adipogenic progenitors, these cells are key players in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ca7e184334f1b0f0d96bcade532594
https://doi.org/10.1016/j.celrep.2022.110785
https://doi.org/10.1016/j.celrep.2022.110785