Zobrazeno 1 - 10
of 345
pro vyhledávání: '"Anthony J, Hannan"'
Autor:
Lucas B. Hoffmann, Evangeline A. McVicar, Rebekah V. Harris, Coralina Collar-Fernández, Michael B. Clark, Anthony J. Hannan, Terence Y. Pang
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Studies have shown that paternal stress prior to conception can influence the innate behaviours of their offspring. The evolutionary impacts of such intergenerational effects are therefore of considerable interest. Our group previ
Externí odkaz:
https://doaj.org/article/35a8deb0963f4c48a308b455459a12f8
Autor:
Clive R. Bramham, Volkmar Lessmann, Anthony J. Hannan, Changhe Wang, Alberto Catanese, Tobias Maria Boeckers, Hongyu Zhang
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 15 (2023)
Externí odkaz:
https://doaj.org/article/438dad54159842b2af11f4fe760ac5bf
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106223- (2023)
Obsessive-compulsive and related disorders (OCRD) is an emergent class of psychiatric illnesses that contributes substantially to the global mental health disease burden. In particular, the prototypical illness, obsessive-compulsive disorder (OCD), h
Externí odkaz:
https://doaj.org/article/6632a74a967745b699c97abd5a82e340
Autor:
Farheen Farzana, Malcolm J. McConville, Thibault Renoir, Shanshan Li, Shuai Nie, Harvey Tran, Anthony J. Hannan, Danny M. Hatters, Berin A. Boughton
Publikováno v:
Neurobiology of Disease, Vol 176, Iss , Pp 105933- (2023)
In Huntington's disease (HD), a key pathological feature includes the development of inclusion-bodies of fragments of the mutant huntingtin protein in the neurons of the striatum and hippocampus. To examine the molecular changes associated with inclu
Externí odkaz:
https://doaj.org/article/076bba59de224e7fbf2275e6dd517b20
Autor:
Chloe J. Love, Carolina Gubert, Saritha Kodikara, Geraldine Kong, Kim-Anh Lê Cao, Anthony J. Hannan
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101772- (2022)
Summary: Fecal samples are frequently used to characterize bacterial populations of the gastrointestinal tract. A protocol is provided to profile gut bacterial populations using rodent fecal samples. We describe the optimal procedures for collecting
Externí odkaz:
https://doaj.org/article/994b64d8645941f88e9791e8ca8abd11
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101689- (2022)
Summary: Here, we present a protocol that allows comparison of the effects of the standard home cage, environmentally enriched home cage with additional super-enrichment, and the exercise (running wheels only) home cage in laboratory mice. We first d
Externí odkaz:
https://doaj.org/article/b293043862404326b66fcc677ed70785
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Huntington’s disease (HD) is a neurodegenerative disorder caused by a trinucleotide expansion in the HTT gene, which is expressed throughout the brain and body, including the gut epithelium and enteric nervous system. Afflicted individuals
Externí odkaz:
https://doaj.org/article/64127441d4964459a2f4edf5c7b3e841
Autor:
Anita J. L. Leembruggen, Yuqing Lu, Haozhe Wang, Volkan Uzungil, Thibault Renoir, Anthony J. Hannan, Lincon A. Stamp, Marlene M. Hao, Joel C. Bornstein
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 139 (2023)
Glutamate is the major excitatory neurotransmitter in the central nervous system, and there is evidence that Group-I metabotropic glutamate receptors (mGlu1 and mGlu5) have established roles in excitatory neurotransmission and synaptic plasticity. Wh
Externí odkaz:
https://doaj.org/article/0822ba6f544e4a85955bb65e6076b976
Publikováno v:
Molecular Autism, Vol 10, Iss 1, Pp 1-21 (2019)
Abstract Cognitive dysfunction including disrupted behavioral flexibility is central to neurodevelopmental disorders such as Autism Spectrum Disorder (ASD). A cognitive measure that assesses relational memory, and the ability to flexibly assimilate a
Externí odkaz:
https://doaj.org/article/6ba674da31b14c35b19b0f3d7cf9968a
Autor:
Amy Shepherd, Tracy Zhang, Lucas B. Hoffmann, Ariel M. Zeleznikow-Johnston, Leonid Churilov, Anthony J. Hannan, Emma L. Burrows
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
With the growing popularity of touchscreen cognitive testing in rodents, it is imperative to understand the fundamental effects exposure to this paradigm can have on the animals involved. In this study, we set out to assess hippocampal-dependant lear
Externí odkaz:
https://doaj.org/article/20ee0742d5844c73b6b479c77b9cc453