Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Anthony I. Shepherd"'
Autor:
Joe Antoun, Anthony I. Shepherd, Jo Corbett, Nicholas C. Sangala, Robert J. Lewis, Emma Lane, Zoe L. Saynor
Publikováno v:
Physiological Reports, Vol 12, Iss 17, Pp n/a-n/a (2024)
Abstract People with end‐stage kidney disease (ESKD) often exhibit impaired cardiac structure and function, which may contribute to poor exercise capacity. This study used multimodal exercise testing to investigate the central and peripheral mechan
Externí odkaz:
https://doaj.org/article/89a3197ad45c4db2b71ec569d6e35acd
Autor:
Jo Corbett, Michael J. Tipton, Maria Perissiou, Thomas James, John S. Young, Alexander Newman, Michael Cummings, Hugh Montgomery, Michael P. W. Grocott, Anthony I. Shepherd
Publikováno v:
Physiological Reports, Vol 11, Iss 9, Pp n/a-n/a (2023)
Abstract Previous research has shown that ≤60 min hypoxic exposure improves subsequent glycaemic control, but the optimal level of hypoxia is unknown and data are lacking from individuals with overweight. We undertook a cross‐over pilot feasibili
Externí odkaz:
https://doaj.org/article/ecb142f915c34ff8bdfd7ac7d265ac01
Autor:
Oliver M. Shannon, Chris Easton, Anthony I. Shepherd, Mario Siervo, Stephen J. Bailey, Tom Clifford
Publikováno v:
BMC Sports Science, Medicine and Rehabilitation, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Background Dietary inorganic nitrate (NO3 −) is a polyatomic ion, which is present in large quantities in green leafy vegetables and beetroot, and has attracted considerable attention in recent years as a potential health-promoting dietary
Externí odkaz:
https://doaj.org/article/ce4b25e002ac446b8e4b4ba0e9a62bda
Autor:
Adam J. Causer, Maha Khalaf, Emily Klein Rot, Kimberly Brand, James Smith, Stephen J. Bailey, Michael H. Cummings, Anthony I. Shepherd, Zoe L. Saynor, Janis K. Shute
Publikováno v:
Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)
Abstract Micro‐ and macrovascular endothelial dysfunction in response to shear stress has been observed in cystic fibrosis (CF), and has been associated with inflammation and oxidative stress. We tested the hypothesis that the cystic fibrosis trans
Externí odkaz:
https://doaj.org/article/15305a003efe46a2a9d40d3c7a267ada
Autor:
Meriel Norris, Leon Poltawski, Raff Calitri, Anthony I. Shepherd, Sarah G. Dean, on behalf of the ReTrain Team
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background Unanticipated responses by research participants can influence randomised controlled trials (RCTs) in multiple ways, many of which are poorly understood. This study used qualitative interviews as part of an embedded process evalua
Externí odkaz:
https://doaj.org/article/c40cc175e7d6481e99632c1cde16c611
Autor:
Adam J. Causer, Janis K. Shute, Michael H. Cummings, Anthony I. Shepherd, Mathieu Gruet, Joseph T. Costello, Stephen Bailey, Martin Lindley, Clare Pearson, Gary Connett, Mark I. Allenby, Mary P. Carroll, Thomas Daniels, Zoe L. Saynor
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Introduction: Oxidative stress may play an important role in the pathophysiology of cystic fibrosis (CF). This review aimed to quantify CF-related redox imbalances. Methods: Systematic searches of the Medline, CINAHL, CENTRAL and PsycINFO databases w
Externí odkaz:
https://doaj.org/article/8cfcf95b8b0c44f4afc9d6b25414b29e
Autor:
Clare M. Eglin, Jennifer Wright, Anthony I. Shepherd, Heather Massey, Sarah Hollis, Jonathan Towse, John S. Young, Matthew J. Maley, Stephen J. Bailey, Chris Wilkinson, Hugh Montgomery, Michael J. Tipton
Publikováno v:
Experimental Physiology. 108:448-464
NEW FINDINGS: What is the central question of this study? Are biomarkers of endothelial function, oxidative stress and inflammation altered by non-freezing cold injury (NFCI)? What is the main finding and its importance? Baseline plasma [interleukin-
Autor:
Adam J. Causer, Janis K. Shute, Michael H. Cummings, Anthony I. Shepherd, Samuel R. Wallbanks, Richard M. Pulsford, Victoria Bright, Gary Connett, Zoe L. Saynor
Publikováno v:
Pediatric Pulmonology. 57:2652-2658
Elexacaftor/Tezacaftor/Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator with the potential to improve exercise capacity. This case series of three adolescents with CF aimed to investigate whether 6 weeks treatment w
Autor:
Joe Antoun, Anthony I. Shepherd, Melitta A. McNarry, Kelly A. Mackintosh, Jo Corbett, Nicholas C. Sangala, Robert J. Lewis, Zoe L. Saynor
Publikováno v:
Journal of Clinical Exercise Physiology. 11:38-43
Background Treatment of end-stage renal disease (ESRD) is necessary to maintain life. However, it can cause physiological, psychosocial, and cognitive impairments, which may impact physical activity (PA) and sleep, although there is insufficient devi
Exploring patients' experiences of the impact of dialysis therapies on quality of life and wellbeing
Autor:
Joe Antoun, Daniel J. Brown, Daniel J. W. Jones, Beth G. Clarkson, Anthony I. Shepherd, Nicholas C. Sangala, Robert J. Lewis, Melitta A. McNarry, Kelly A. Mackintosh, Laura Mason, Jo Corbett, Zoe L. Saynor
Publikováno v:
Journal of Renal Care. 49:15-23
When people with chronic kidney disease reach kidney failure, renal replacement therapy is usually required to improve symptoms and maintain life. Although in-centre haemodialysis is most commonly used for this purpose, other forms of dialysis are av