Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anthony High"'
Autor:
Timothy I. Shaw, Li Dong, Liqing Tian, Chenxi Qian, Yu Liu, Bensheng Ju, Anthony High, Kanisha Kavdia, Vishwajeeth R. Pagala, Bridget Shaner, Deqing Pei, John Easton, Laura J. Janke, Shaina N. Porter, Xiaotu Ma, Cheng Cheng, Shondra M. Pruett-Miller, John Choi, Jiyang Yu, Junmin Peng, Wei Gu, A. Thomas Look, James R. Downing, Jinghui Zhang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract USP7, which encodes a deubiquitylating enzyme, is among the most frequently mutated genes in pediatric T-ALL, with somatic heterozygous loss-of-function mutations (haploinsufficiency) predominantly affecting the subgroup that has aberrant TA
Externí odkaz:
https://doaj.org/article/cb7c285f227c42abb04cd250bb2d752a
Autor:
Zoran Rankovic, Gisele Nishiguchi, Sherif Abdelhamed, Sarah Young, Elizabeth Caine, Lauren Mascibroda, Jeffrey Kooijman, Sourav Das, Darcie Miller, Kevin McGowan, Anand Mayasundari, Zhe Shi, Juan Barajas, Ryan Hiltenbrand, Anup Aggarwal, Yunchao Chang, Vibhor Mishra, Ravi Kalathur, Junmin Peng, Shondra Pruett-Miller, Danette Daniels, Marjeta Urh, Anang Shelat, Charles Mullighan, Kristin Riching, Guido Zaman, Marcus Fischer, Jeffery Klco, Shilpa Narina, Allister Loughran, Anthony High
While the PROTAC approach to targeted protein degradation greatly benefits from rational design, the discovery of molecular glue degraders currently relies on screening strategies. Here, we describe screening of a library containing 3,630 cereblon bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11f99fdfcf76b30197d41aed82ba9b1d
https://doi.org/10.21203/rs.3.rs-2883533/v1
https://doi.org/10.21203/rs.3.rs-2883533/v1
Autor:
Jia Xie, Teneema Kuriakose, Brandon Bianski, Nathaniel Twarog, Evan Savage, Ke Xu, Xiaoyan Zhu, Chen He, Baranda Hansen, Hong Wang, Anthony High, Yuxin Li, Jerold E Rehg, Heather S Tillman, Burgess B Freeman, Zoran Rankovic, Arzu Onar-Thomas, Yiping Fan, Gang Wu, Junmin Peng, Shondra Miller, Suzanne J Baker, Anang A Shelat, Christopher L Tinkle
Publikováno v:
Neuro-Oncology.
Background Pediatric high-grade glioma (pHGG) is largely incurable and accounts for most brain tumor-related deaths in children. Radiation is a standard therapy, yet the benefit from this treatment modality is transient, and most children succumb to
Autor:
Tizita Z. Zeleke, Qingfei Pan, Codruta Chiuzan, Maika Onishi, Yuxin Li, Haiyan Tan, Mariano J. Alvarez, Erin Honan, Min Yang, Pei Ling Chia, Partha Mukhopadhyay, Sean Kelly, Ruby Wu, Kathleen Fenn, Meghna S. Trivedi, Melissa Accordino, Katherine D. Crew, Dawn L. Hershman, Matthew Maurer, Simon Jones, Anthony High, Junmin Peng, Andrea Califano, Kevin Kalinsky, Jiyang Yu, Jose Silva
Publikováno v:
Nature cancer.
Inhibiting individual histone deacetylase (HDAC) is emerging as well-tolerated anticancer strategy compared with pan-HDAC inhibitors. Through preclinical studies, we demonstrated that the sensitivity to the leading HDAC6 inhibitor (HDAC6i) ricolinsta
Autor:
Aguwa C; School of Medicine, Meharry Medical College, Nashville, Tennessee, USA., Enwereji N; Frank H. Netter MD School of Medicine, Quinnipiac University, North Haven, Connecticut, USA., Santiago S; Department of Dermatology, University of Connecticut Health Center, Farmington, Connecticut, USA., Hine A; Department of Dermatology, University of Connecticut Health Center, Farmington, Connecticut, USA., Kels GG; St. Anthony High School, San Antonio, Texas, USA., McGee J; Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Lu J; Department of Dermatology, University of Connecticut Health Center, Farmington, Connecticut, USA. Electronic address: jlu@uchc.edu.
Publikováno v:
Clinics in dermatology [Clin Dermatol] 2023 Sep-Oct; Vol. 41 (5), pp. 640-649. Date of Electronic Publication: 2023 Oct 09.
Autor:
Zhang X; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA., Sun H; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA., Wang Z; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA., Zhou S; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN, USA., Fu Y; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA., Anthony HA; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN, USA., Peng J; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA. junmin.peng@stjude.org.; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN, USA. junmin.peng@stjude.org.
Publikováno v:
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2628, pp. 109-125.