Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Anthony H. Olavesen"'
Publikováno v:
Carbohydrate Research. 208:306-311
Publikováno v:
Biochemical pharmacology. 41(9)
In this paper we report on the use of biotin-labelled hyaluronidase for the analysis of the serum kinetics, tissue distribution and sub-cellular localization of normal and deglycosylated enzyme in the rat
Publikováno v:
Biochemical Society transactions. 18(3)
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 17:793-800
DL-[2-14C]Octan-2-sulPhate was prepared by sulphating DL-[2-14C]octan-2-ol with pyridine-SO3 adduct. Synthesis of the DL-[2-14C]alkanol started with carboxylation of hexyl magnesium bromide with 14CO2. Subsequent methylation with diazomethane and red
Publikováno v:
Xenobiotica. 6:667-678
1. The metabolism of the odd-numbered carbon chain surfactant, potassium undecyl [35S]sulphate in the rat was investigated. 2. The major route for elimination of radioactivity was the urine, regardless of the route of administration. 3. The surfactan
Publikováno v:
Toxicology and Applied Pharmacology. 45:105-117
When [1-14C]dodecyl sulfonate and [1-14C]hexadecyl sulfonate were administered orally and ip to free-ranging rats and iv to anesthetized rats, the major route of excretion of radioactivity was urinary. Small amounts only of parent surfactant appeared
Autor:
Peter Gacesa, Kenneth S. Dodgson, C. G. Curtis, Anthony H. Olavesen, Julia S. Earnshaw, Gillian M. Powell
Publikováno v:
Biochemical Pharmacology. 34:2199-2203
A highly purified commercial preparation of bovine testicular hyaluronidase (GL enzyme, Hyalosidase) was labelled with 125 iodine without measurable loss of enzyme activity. The labelled preparation was administered intravenously into rats and the se
Publikováno v:
Biochemical Journal. 168:373-377
The metabolic fates and modes of excretion of diethylstilboestrol mono[35S]sulphate and diethylstilboestrol di[35S]sulphate were studied in the guinea pig. Comparative studies were also made with [G-3H]diethylstilboestrol and phenolphthalein di[35S]s
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Enzymology. 661:205-212
Purified bovine testicular hyaluronidase (hyaluronate 4-glycanohydrolase, EC 3.2.1.35) was inactivated by butane-2,3-dione in either borate or Hepes buffer, pH 8.3. The presence of borate enhanced the inactivation process which followed pseudo-first-
Publikováno v:
Journal of Labelled Compounds. 10:151-160
The preparation of 2, 6-dimethoxy [U-14C]phenol was carried out in five steps from [U-14C]phenol. [U-14C]Phenol was converted to 2-[U-14C]phenoxy-5-nitrobenzophenone which was sequentially hydroxylated with hydrogen peroxide-acetic acid to give the d