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pro vyhledávání: '"Anthony H. Davies"'
New Gene Therapy CMC Guidance from the FDA – A Breakthrough in Regulation or Something More Generic?
Autor:
Anthony H Davies
Publikováno v:
Cell and Gene Therapy Insights. 4:647-652
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ea76bed6171ee5ec8d69a6a6a8d8e25
https://doi.org/10.18609/cgti.2018.062
https://doi.org/10.18609/cgti.2018.062
Autor:
Nicholas E. Timmins, Anthony H. Davies, Peter W. Zandstra, Yonatan Y. Lipsitz, Patrick Bedford
Publikováno v:
Cell stem cell. 20(1)
New methods to manipulate gene and cell state can be used to engineer cell functionality, simplify quality assessment, and enhance manufacturability. These strategies could help overcome unresolved cell therapy manufacturing challenges and complement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d217690934b385b99fa621a5ae3e50
https://pubmed.ncbi.nlm.nih.gov/28061350
https://pubmed.ncbi.nlm.nih.gov/28061350
Autor:
Anthony H Davies
Publikováno v:
Current Opinion in Biotechnology. 6:543-547
Recombinant baculoviruses are widely used to express heterologous proteins. They are particularly useful for the high-level expression of eukaryotic proteins with fastidious co- or post-translational processing requirements. The recent publication of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d9cd9570ce9fb58bbaa8c88ee3cc5b3
https://doi.org/10.1016/0958-1669(95)80090-5
https://doi.org/10.1016/0958-1669(95)80090-5
Autor:
Anthony H. Davies
Publikováno v:
Nature Biotechnology. 12:47-50
Recombinant baculoviruses have become popular expression vectors for heterologous proteins. Recently, several novel strategies for manipulating the baculovirus genome have been developed. These include linearizing the viral genome at the point of ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d4af3e1471cba46812d283cf4a8ca7e
https://doi.org/10.1038/nbt0194-47
https://doi.org/10.1038/nbt0194-47
Publikováno v:
Nature Biotechnology. 11:933-936
Recombinant baculoviruses are a popular means of producing heterologous protein in eukaryotic cells. Purification of recombinant proteins away from the insect cell background can, however, remain an obstacle for many developments. Recently, prokaryot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a28707ab0fb45cd02482b9a6cd9aa7
https://doi.org/10.1038/nbt0893-933
https://doi.org/10.1038/nbt0893-933
Autor:
Anthony H. Davies
Publikováno v:
Bio/technology (Nature Publishing Company). 13(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f74f0dedf263eabbda06e5641d059b
https://pubmed.ncbi.nlm.nih.gov/9636281
https://pubmed.ncbi.nlm.nih.gov/9636281
Publikováno v:
Virology. 208(1)
We describe the use of a new baculovirus expression vector to enable the secretion of the major surface glycoprotein of HIV-1 (gp120) fused to the carboxy-terminus of the widely used affinity tag glutathione S -transferase. The secreted protein can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2a57306fa1422c1b2ccb8bd3fa13e6
https://pubmed.ncbi.nlm.nih.gov/11831694
https://pubmed.ncbi.nlm.nih.gov/11831694
Publikováno v:
Virology. 202(2)
Study of the human papillomavirus (HPV) E4 gene product has focused largely on HPV type 1 (HPV 1) primarily because of the large quantities of protein that can be purified from HPV 1-induced warts. We have extended the characterization of the HPV 1 E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f72b7941518da53ec7ce8eb0e6dd3d
https://pubmed.ncbi.nlm.nih.gov/7518163
https://pubmed.ncbi.nlm.nih.gov/7518163