Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anthony H. Bianchi"'
Autor:
Adele S. Ricciardi, Raman Bahal, James S. Farrelly, Elias Quijano, Anthony H. Bianchi, Valerie L. Luks, Rachael Putman, Francesc López-Giráldez, Süleyman Coşkun, Eric Song, Yanfeng Liu, Wei-Che Hsieh, Danith H. Ly, David H. Stitelman, Peter M. Glazer, W. Mark Saltzman
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The correction of genetic defects in utero could allow for improved outcomes of gene therapy. Here, the authors demonstrate safe delivery of nanoparticles to fetal mouse tissues, and show that nanoparticles containing peptide nucleic acids to edit th
Externí odkaz:
https://doaj.org/article/adf52524b8364f4a87460fa79da2c6f9
Autor:
Paul S Campbell, Mauro Provinciali, Andrea Basso, Kathleen Kelly, Kelsey Moody, Marco Malavolta, Anthony H Bianchi, Cheyanne Fisher, Ellie Lumen, Giovanni Lai, Douglas Hagrman, Roger G Bagg, Kristopher James Grohn, Cristina Nicoletti, Danique Wortel, Brandon Scott Moyer, Aaron J. Wolfe, James Clement
Publikováno v:
GeroScience
C(60) is a potent antioxidant that has been reported to substantially extend the lifespan of rodents when formulated in olive oil (C(60)-OO) or extra virgin olive oil (C60-EVOO). Despite there being no regulated form of C(60)-OO, people have begun ob
Autor:
James S. Farrelly, Anthony H. Bianchi, Adele S. Ricciardi, Gina Buzzelli, Valerie L. Luks, W. Mark Saltzman, David H. Stitelman, Samantha L. Ahle, Mollie R. Freedman-Weiss
Publikováno v:
Journal of Pediatric Surgery. 54:80-85
We sought to develop a minimally invasive intra-amniotic therapy for prenatal treatment of myelomeningocele (MMC) in an established rat model.Time-dated pregnant rats were gavage-fed retinoic acid to induce MMC. Groups received intraamniotic injectio
Autor:
Anthony H. Bianchi, Eric Song, W. Mark Saltzman, David H. Stitelman, Francesc López-Giráldez, James S. Farrelly, Peter M. Glazer, Elias Quijano, Valerie L. Luks, Danith H. Ly, Adele S. Ricciardi, Rachael Putman, Raman Bahal, Yanfeng Liu, Süleyman Coşkun, Wei-Che Hsieh
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
Genetic diseases can be diagnosed early during pregnancy, but many monogenic disorders continue to cause considerable neonatal and pediatric morbidity and mortality. Early intervention through intrauterine gene editing, however, could correct the gen
Autor:
Aaron J. Wolfe, Meegan B. Sleeper, Jennifer R. DeRosa, Connor McGuigan, Kelsey Moody, Brandon S. Moyer, Ashleigh Crawford, Anthony H Bianchi, Adam R. Blanden, Danique Wortel, Ellie Lumen, Cheyanne Fisher
Publikováno v:
Biochemistry. 57:3036-3049
Antibodies are the most prolific biologics in research and clinical environments because of their ability to bind targets with high affinity and specificity. However, antibodies also carry liabilities. A significant portion of the life-science reprod
Autor:
Jennifer R. DeRosa, Ellie Lumen, Kelsey Moody, Brandon S. Moyer, Justin Applegate, Jay Tinklepaugh, Meegan B. Sleeper, Danique Wortel, Emily Leary, Scott Campbell, Cheyanne Fisher, Baerbel Rohrer, Robert P. Doyle, Nicholas LeClair, Kris Grohn, Aaron J. Wolfe, Anthony H Bianchi, Adam R. Blanden, Elisabeth Obert
Publikováno v:
Rejuvenation research. 21(6)
Macular degeneration is hallmarked by retinal accumulation of toxic retinoid species (e.g., A2E) for which there is no endogenous mechanism to eliminate it. This ultimately results in progressive dysfunction and loss of vision either in advanced age