Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anthony Gerard Doyle"'
Autor:
Danyal Butt, Jacquelyn Lyons, Matthew Pollard, Anthony Gerard Doyle, Chen Tian, Doris Shim, Jean Husten, David Mabon, Lynn Dorothy Poulton, Adam Clarke, Vanya Pande
Publikováno v:
mAbs
TL1A is an attractive therapeutic target for the treatment of mucosal inflammation associated with inflammatory bowel disease (IBD) and asthma. Blockade of the TL1A pathway has been shown to reduce inflammatory responses while leaving baseline immuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654c0360ea2a1513a8b707f3d470befb
https://doi.org/10.1080/19420862.2018.1440164
https://doi.org/10.1080/19420862.2018.1440164
Autor:
Karolina Windloch, Matilda Lindgren, Chen Tian, Lynn Dorothy Poulton, Beau Corazon, Teresa Domagala, David Mabon, Jonathan Kannan Nambiar, Adam Clarke, Matthew Pollard, Chris Buhmann, Anthony Gerard Doyle, Doris Shim
Publikováno v:
mAbs
CD1d is a receptor on antigen-presenting cells involved in triggering cell populations, particularly natural killer T (NKT) cells, to release high levels of cytokines. NKT cells are implicated in asthma pathology and blockade of the CD1d/NKT cell pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db30e08f241b14067d039a8065ac8367
http://europepmc.org/articles/PMC4623119
http://europepmc.org/articles/PMC4623119
Autor:
Laurie Pukac, Anthony Gerard Doyle, Jacquelyn Lyons, Jean Husten, David Mabon, Adam Clarke, Mark T. Liddament, Tanya Estephan, David Jose Simon Laine
Publikováno v:
Allergy, Asthma & Immunology Research. 11:291
Reslizumab and mepolizumab are recently approved monoclonal antibodies for the treatment of severe (uncontrolled) eosinophilic asthma. Both are effective in neutralizing the function of interleukin-5 (IL-5). This study is the first to compare the bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb6a44f168394b55c103983a312f94f2
https://doi.org/10.4168/aair.2019.11.2.291
https://doi.org/10.4168/aair.2019.11.2.291
Autor:
David X. Liu, Karol Sestak, Pyone P. Aye, Charles P. Moehs, Adam Clarke, Anthony Gerard Doyle, David Jose Simon Laine, Xavier Alvarez, Jason Dufour, Hazel Thwin, James Blanchard
Publikováno v:
Nutrients
Nutrients; Volume 8; Issue 7; Pages: 401
Nutrients, Vol 8, Iss 7, p 401 (2016)
Nutrients; Volume 8; Issue 7; Pages: 401
Nutrients, Vol 8, Iss 7, p 401 (2016)
Celiac disease (CD) is an autoimmune disorder that affects approximately three million people in the United States. Furthermore, non-celiac gluten sensitivity (NCGS) affects an estimated additional 6% of the population, e.g., 20 million in the U.S. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e2e8736821561903cb31f7d70d5648
http://europepmc.org/articles/PMC4963877
http://europepmc.org/articles/PMC4963877
Autor:
Phil A. Jennings, Danyal Butt, Anthony Gerard Doyle, Teresa Domagala, Nina Shewmaker, Lynn Dorothy Poulton, Stuart A. Walker, Dragana Mraovic, Hoi Yi Wai, Adam Clarke, Shanti David Victor
Publikováno v:
mAbs. 2(5)
While current therapeutic antibodies bind to IL-12 and IL-23 and inhibit their binding to IL-12Rβ1, we describe a novel antibody, termed 6F6, that binds to IL-12 and IL-23 and inhibits the interaction of IL-12 and IL-23 with their cognate signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22760229f7e798813c3ecbd81cc3bbb
https://pubmed.ncbi.nlm.nih.gov/20724822
https://pubmed.ncbi.nlm.nih.gov/20724822
Autor:
Anthony Gerard Doyle, Tetsuya Taura, Maxwell Stevens, Mingying Bi, Sarah L. Pogue, Collette Behrens, Teresa Domagala, Glen E Mikesell, David M. Wilson, Yong Yun, Hussein Hallak, Maya Sokolovsky, Moti Rosenstock, Angela Sho
Publikováno v:
Cytokine. 76:66
Many cytokines have potential therapeutic applications and several, including type I interferons (IFN), have been approved for the treatment of cancer and/or autoimmune disease. While these agents are effective, they are associated with dose-limiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ff3ab9eb3b26f2d9f7a8b84c63de00a
https://doi.org/10.1016/j.cyto.2015.08.047
https://doi.org/10.1016/j.cyto.2015.08.047
Autor:
Glen E Mikesell, Angela Sho, Yong Yun, Tetsuya Taura, Sarah L. Pogue, David M. Wilson, Teresa Domagala, Mingying Bi, Haiming Chen, Hussein Hallak, Maya Sokolovsky, Maxwell Stevens, Eric Sanchez, James R. Berenson, Moti Rosenstock, Anthony Gerard Doyle, Collette Behrens
Publikováno v:
Clinical Cancer Research. 21:A13-A13
Multiple myeloma (MM) remains an incurable disease despite recent approvals of novel therapies. Treatments which utilize alkylating agents, corticosteroids, proteasome inhibitors and immunomodulatory drugs have provided significant survival benefits;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2195b1618d6932a8d2c2efad28bb5d0
https://doi.org/10.1158/1557-3265.hemmal14-a13
https://doi.org/10.1158/1557-3265.hemmal14-a13
Autor:
Sarah L. Pogue, Collette Behrens, Teresa Domagala, Tetsuya Taura, David S. Wilson, Maxwell Stevens, Anthony Gerard Doyle, Yong Yun, Angela Sho, Maya Sokolovsky, Hussein Hallak, Moti Rosenstock, Mingying Bi, Glen E Mikesell
Publikováno v:
Cancer Research. 74:2660-2660
Many cytokines have potential therapeutic applications and several, including interferon (IFN)α and IFNβ, have been approved for the treatment of cancer and/or autoimmune disease. While these agents are effective, they are associated with significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ca6f213603286952b9b6081816900de
https://doi.org/10.1158/1538-7445.am2014-2660
https://doi.org/10.1158/1538-7445.am2014-2660