Risk prediction of 30-day mortality after stroke using machine learning: a nationwide registry-based cohort study

Autor: Wenjuan Wang, Anthony G. Rudd, Yanzhong Wang, Vasa Curcin, Charles D. Wolfe, Niels Peek, Benjamin Bray

Publikováno v: BMC Neurology, Vol 22, Iss 1, Pp 1-9 (2022)

Abstract Backgrounds We aimed to develop and validate machine learning (ML) models for 30-day stroke mortality for mortality risk stratification and as benchmarking models for quality improvement in stroke care. Methods Data from the UK Sentinel Stro

Externí odkaz: https://doaj.org/article/231bca87b111469bbe4b551cf2fa44a1

The potential role of cost-utility analysis in the decision to implement major system change in acute stroke services in metropolitan areas in England

Autor: Rachael M. Hunter, Naomi J. Fulop, Ruth J. Boaden, Christopher McKevitt, Catherine Perry, Angus I. G. Ramsay, Anthony G. Rudd, Simon J. Turner, Pippa J. Tyrrell, Charles D. A. Wolfe, Stephen Morris

Publikováno v: Health Research Policy and Systems, Vol 16, Iss 1, Pp 1-14 (2018)

Abstract Background The economic implications of major system change are an important component of the decision to implement health service reconfigurations. Little is known about how best to report the results of economic evaluations of major system

Externí odkaz: https://doaj.org/article/8a04e6e9f3bf4fb28327429af2658f81

What does it take to provide clinical interventions with temporal consistency? A qualitative study of London hyperacute stroke units

Autor: Martin M Brown, Stephen Morris, Robert Simister, Naomi J Fulop, Angus I G Ramsay, Anthony G Rudd, Penny Xanthopoulou, Mariya Melnychuk, Jeannie Eng, Abigail Baim-Lance, Georgia B Black

Publikováno v: BMJ Open, Vol 9, Iss 11 (2019)

Objectives Seven-day working in hospitals is a current priority of international health research and policy. Previous research has shown variability in delivering evidence-based clinical interventions across different times of day and week. We aimed

Externí odkaz: https://doaj.org/article/444f75b156e3455fab785d4f5ccc56bb

Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations

Autor: Gerard Temprano‐Sagrera, Colleen M. Sitlani, William P. Bone, Miguel Martin‐Bornez, Benjamin F. Voight, Alanna C. Morrison, Scott M. Damrauer, Paul S. de Vries, Nicholas L. Smith, Maria Sabater‐Lleal, Abbas Dehghan, Adam S Heath, Alanna C Morrison, Alex P Reiner, Andrew Johnson, Anne Richmond, Annette Peters, Astrid van Hylckama Vlieg, Barbara McKnight, Bruce M Psaty, Caroline Hayward, Cavin Ward‐Caviness, Christopher O’Donnell, Daniel Chasman, David P Strachan, David A Tregouet, Dennis Mook‐Kanamori, Dipender Gill, Florian Thibord, Folkert W Asselbergs, Frank W.G. Leebeek, Frits R Rosendaal, Gail Davies, Georg Homuth, Gerard Temprano, Harry Campbell, Herman A Taylor, Jan Bressler, Jennifer E Huffman, Jerome I Rotter, Jie Yao, James F Wilson, Joshua C Bis, Julie M Hahn, Karl C Desch, Kerri L Wiggins, Laura M Raffield, Lawrence F Bielak, Lisa R Yanek, Marcus E Kleber, Martina Mueller, Maryam Kavousi, Massimo Mangino, Melissa Liu, Michael R Brown, Matthew P Conomos, Min‐A Jhun, Ming‐Huei Chen, Moniek P.M. de Maat, Nathan Pankratz, Nicholas L Smith, Patricia A Peyser, Paul Elliot, Paul S de Vries, Peng Wei, Philipp S Wild, Pierre E Morange, Pim van der Harst, Qiong Yang, Ngoc‐Quynh Le, Riccardo Marioni, Ruifang Li, Scott M Damrauer, Simon R Cox, Stella Trompet, Stephan B Felix, Uwe Völker, Weihong Tang, Wolfgang Koenig, J. Wouter Jukema, Xiuqing Guo, Sara Lindstrom, Lu Wang, Erin N Smith, William Gordon, Mariza de Andrade, Jennifer A Brody, Jack W Pattee, Jeffrey Haessler, Ben M Brumpton, Daniel I Chasman, Pierre Suchon, Constance Turman, Marine Germain, James MacDonald, Sigrid K Braekkan, Sebastian M Armasu, Rabecca D Jackson, Jonas B Nielsen, Franco Giulianini, Marja K Puurunen, Manal Ibrahim, Susan R Heckbert, Theo K Bammler, Kelly A Frazer, Bryan M McCauley, Kent Taylor, James S Pankow, Alexander P Reiner, Maiken E Gabrielsen, Jean‐François Deleuze, Chris J O’Donnell, Jihye Kim, Peter Kraft, John‐Bjarne Hansen, John A Heit, Charles Kooperberg, Kristian Hveem, Paul M Ridker, Pierre‐Emmanuel Morange, Andrew D Johnson, Christopher Kabrhel, David‐Alexandre Trégouët, Rainer Malik, Ganesh Chauhan, Matthew Traylor, Muralidharan Sargurupremraj, Yukinori Okada, Aniket Mishra, Loes Rutten‐Jacobs, Anne‐Katrin Giese, Sander W van der Laan, Solveig Gretarsdottir, Christopher D Anderson, Michael Chong, Hieab HH Adams, Tetsuro Ago, Peter Almgren, Philippe Amouyel, Hakan Ay, Traci M Bartz, Oscar R Benavente, Steve Bevan, Giorgio B Boncoraglio, Robert D Brown, Adam S Butterworth, Caty Carrera, Cara L Carty, Wei‐Min Chen, John W Cole, Adolfo Correa, Ioana Cotlarciuc, Carlos Cruchaga, John Danesh, Paul IW de Bakker, Anita L DeStefano, Marcel den Hoed, Qing Duan, Stefan T Engelter, Guido J Falcone, Rebecca F Gottesman, Raji P Grewal, Vilmundur Gudnason, Stefan Gustafsson, Tamara B Harris, Ahamad Hassan, Aki S Havulinna, Elizabeth G Holliday, George Howard, Fang‐Chi Hsu, Hyacinth I Hyacinth, M Arfan Ikram, Erik Ingelsson, Marguerite R Irvin, Xueqiu Jian, Jordi Jiménez‐Conde, Julie A Johnson, J Wouter Jukema, Masahiro Kanai, Keith L Keene, Brett M Kissela, Dawn O Kleindorfer, Michiaki Kubo, Leslie A Lange, Carl D Langefeld, Claudia Langenberg, Lenore J Launer, Jin‐Moo Lee, Robin Lemmens, Didier Leys, Cathryn M Lewis, Wei‐Yu Lin, Arne G Lindgren, Erik Lorentzen, Patrik K Magnusson, Jane Maguire, Ani Manichaikul, Patrick F McArdle, James F Meschia, Braxton D Mitchell, Thomas H Mosley, Michael A Nalls, Toshiharu Ninomiya, Martin J O’Donnell, Sara L Pulit, Kristiina Rannikmäe, Kathryn M Rexrode, Kenneth Rice, Stephen S Rich, Natalia S Rost, Peter M Rothwell, Tatjana Rundek, Ralph L Sacco, Saori Sakaue, Michele M Sale, Veikko Salomaa, Bishwa R Sapkota, Reinhold Schmidt, Carsten O Schmidt, Ulf Schminke, Pankaj Sharma, Agnieszka Slowik, Cathie LM Sudlow, Christian Tanislav, Turgut Tatlisumak, Kent D Taylor, Vincent NS Thijs, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Steffen Tiedt, Christophe Tzourio, Cornelia M van Duijn, Matthew Walters, Nicholas J Wareham, Sylvia Wassertheil‐Smoller, James G Wilson, Salim Yusuf, Najaf Amin, Hugo S Aparicio, Donna K Arnett, John Attia, Alexa S Beiser, Claudine Berr, Julie E Buring, Mariana Bustamante, Valeria Caso, Yu‐Ching Cheng, Seung Hoan Choi, Ayesha Chowhan, Natalia Cullell, Jean‐François Dartigues, Hossein Delavaran, Pilar Delgado, Marcus Dörr, Gunnar Engström, Ian Ford, Wander S Gurpreet, Anders Hamsten, Laura Heitsch, Atsushi Hozawa, Laura Ibanez, Andreea Ilinca, Martin Ingelsson, Motoki Iwasaki, Rebecca D Jackson, Katarina Jood, Pekka Jousilahti, Sara Kaffashian, Lalit Kalra, Masahiro Kamouchi, Takanari Kitazono, Olafur Kjartansson, Manja Kloss, Peter J Koudstaal, Jerzy Krupinski, Daniel L Labovitz, Cathy C Laurie, Christopher R Levi, Linxin Li, Lars Lind, Cecilia M Lindgren, Vasileios Lioutas, Yong Mei Liu, Oscar L Lopez, Hirata Makoto, Nicolas Martinez‐Majander, Koichi Matsuda, Naoko Minegishi, Joan Montaner, Andrew P Morris, Elena Muiño, Martina Müller‐Nurasyid, Bo Norrving, Soichi Ogishima, Eugenio A Parati, Leema Reddy Peddareddygari, Nancy L Pedersen, Joanna Pera, Markus Perola, Alessandro Pezzini, Silvana Pileggi, Raquel Rabionet, Iolanda Riba‐Llena, Marta Ribasés, Jose R Romero, Jaume Roquer, Anthony G Rudd, Antti‐Pekka Sarin, Ralhan Sarju, Chloe Sarnowski, Makoto Sasaki, Claudia L Satizabal, Mamoru Satoh, Naveed Sattar, Norie Sawada, Gerli Sibolt, Ásgeir Sigurdsson, Albert Smith, Kenji Sobue, Carolina Soriano‐Tárraga, Tara Stanne, O Colin Stine, David J Stott, Konstantin Strauch, Takako Takai, Hideo Tanaka, Kozo Tanno, Alexander Teumer, Liisa Tomppo, Nuria P Torres‐Aguila, Emmanuel Touze, Shoichiro Tsugane, Andre G Uitterlinden, Einar M Valdimarsson, Sven J van der Lee, Henry Völzke, Kenji Wakai, David Weir, Stephen R Williams, Charles DA Wolfe, Quenna Wong, Huichun Xu, Taiki Yamaji, Dharambir K Sanghera, Olle Melander, Christina Jern, Daniel Strbian, Israel Fernandez‐Cadenas, W T Longstreth, Arndt Rolfs, Jun Hata, Daniel Woo, Jonathan Rosand, Guillaume Pare, Jemma C Hopewell, Danish Saleheen, Kari Stefansson, Bradford B Worrall, Steven J Kittner, Sudha Seshadri, Myriam Fornage, Hugh S Markus, Joanna MM Howson, Yoichiro Kamatani, Stephanie Debette, Martin Dichgans

Publikováno v: Temprano-Sagrera, G, Sitlani, C M, Bone, W P, Martin-Bornez, M, Voight, B F, Morrison, A C, Damrauer, S M, de Vries, P S, Smith, N L, Sabater-Lleal, M, Dehghan, A, Heath, A S, Morrison, A C, Reiner, A P, Johnson, A, Richmond, A, Peters, A, van Hylckama Vlieg, A, McKnight, B, Psaty, B M, Hayward, C, Ward-Caviness, C, O’Donnell, C, Chasman, D I, Strachan, D P, Trégouët, D A, Mook-Kanamori, D, Gill, D, Thibord, F, Asselbergs, F W, Leebeek, F W G, Rosendaal, F R, Davies, G, Homuth, G, Temprano, G, Campbell, H, Taylor, H A, Bressler, J, Huffman, J E, Rotter, J I, Yao, J, Wilson, J F, Bis, J C, Hahn, J M, Desch, K C, Wiggins, K L, Raffield, L M, Bielak, L F, Yanek, L R, Kleber, M E, Sabater-Lleal, M, Mueller, M, Kavousi, M, Mangino, M, Liu, M, Brown, M R, Conomos, M P, Jhun, M A, Chen, M H, de Maat, M P M, Pankratz, N, Smith, N L, Peyser, P A, Elliot, P, de Vries, P S, Wei, P, Wild, P S, Morange, P E, van der Harst, P, Yang, Q, Le, N Q, Marioni, R, Li, R, Damrauer, S M, Cox, S R, Trompet, S, Felix, S B, Völker, U, Tang, W, Koenig, W, Jukema, J W, Guo, X, Lindstrom, S, Wang, L, Smith, E N, Gordon, W, van Hylckama Vlieg, A, de Andrade, M, Brody, J A, Pattee, J W, Haessler, J, Brumpton, B M, Chasman, D I, Suchon, P, Chen, M H, Turman, C, Germain, M, Wiggins, K L, MacDonald, J, Braekkan, S K, Armasu, S M, Pankratz, N, Jackson, R D, Nielsen, J B, Giulianini, F, Puurunen, M K, Ibrahim, M, Heckbert, S R, Bammler, T K, Frazer, K A, McCauley, B M, Taylor, K D, Pankow, J S, Reiner, A P, Gabrielsen, M E, Deleuze, J F, O’Donnell, C J, Kim, J, McKnight, B, Kraft, P, Hansen, J B, Rosendaal, F R, Heit, J A, Psaty, B M, Tang, W, Kooperberg, C, Hveem, K, Ridker, P M, Morange, P E, Johnson, A, Kabrhel, C, Trégouët, D A, Smith, N L, Malik, R, Chauhan, G, Traylor, M, Sargurupremraj, M, Okada, Y, Mishra, A, Rutten-Jacobs, L, Giese, A K, van der Laan, S W, Gretarsdottir, S, Anderson, C D, Chong, M, Adams, H H H, Ago, T, Almgren, P, Amouyel, P, Ay, H, Bartz, T M, Benavente, O R, Bevan, S, Boncoraglio, G B, Brown, R D, Butterworth, A S, Carrera, C, Carty, C L, Chasman, D I, Chen, W M, Cole, J W, Correa, A, Cotlarciuc, I, Cruchaga, C, Danesh, J, de Bakker, P I W, DeStefano, A L, den Hoed, M, Duan, Q, Engelter, S T, Falcone, G J, Gottesman, R F, Grewal, R P, Gudnason, V, Gustafsson, S, Haessler, J, Harris, T B, Hassan, A, Havulinna, A S, Heckbert, S R, Holliday, E G, Howard, G, Hsu, F C, Hyacinth, H I, Arfan Ikram, M, Ingelsson, E, Irvin, M R, Jian, X, Jiménez-Conde, J, Johnson, J A, Jukema, J W, Kanai, M, Keene, K L, Kissela, B M, Kleindorfer, D O, Kooperberg, C, Kubo, M, Lange, L A, Langefeld, C D, Langenberg, C, Launer, L J, Lee, J M, Lemmens, R, Leys, D, Lewis, C M, Lin, W Y, Lindgren, A G, Lorentzen, E, Magnusson, P K, Maguire, J, Manichaikul, A, McArdle, P F, Meschia, J F, Mitchell, B D, Mosley, T H, Nalls, M A, Ninomiya, T, O’Donnell, M J, Psaty, B M, Pulit, S L, Rannikmäe, K, Reiner, A P, Rexrode, K M, Rice, K, Rich, S S, Ridker, P M, Rost, N S, Rothwell, P M, Rotter, J I, Rundek, T, Sacco, R L, Sakaue, S, Sale, M M, Salomaa, V, Sapkota, B R, Schmidt, R, Schmidt, C O, Schminke, U, Sharma, P, Slowik, A, Sudlow, C L M, Tanislav, C, Tatlisumak, T, Taylor, K D, Thijs, V N S, Thorleifsson, G, Thorsteinsdottir, U, Tiedt, S, Trompet, S, Tzourio, C, van Duijn, C M, Walters, M, Wareham, N J, Wassertheil-Smoller, S, Wilson, J F, Wiggins, K L, Yang, Q, Yusuf, S, Amin, N, Aparicio, H S, Arnett, D K, Attia, J, Beiser, A S, Berr, C, Buring, J E, Bustamante, M, Caso, V, Cheng, Y C, Hoan Choi, S, Chowhan, A, Cullell, N, Dartigues, J F, Delavaran, H, Delgado, P, Dörr, M, Engström, G, Ford, I, Gurpreet, W S, Hamsten, A, Heitsch, L, Hozawa, A, Ibanez, L, Ilinca, A, Ingelsson, M, Iwasaki, M, Jackson, R D, Jood, K, Jousilahti, P, Kaffashian, S, Kalra, L, Kamouchi, M, Kitazono, T, Kjartansson, O, Kloss, M, Koudstaal, P J, Krupinski, J, Labovitz, D L, Laurie, C C, Levi, C R, Li, L, Lind, L, Lindgren, C M, Lioutas, V, Mei Liu, Y, Lopez, O L, Makoto, H, Martinez-Majander, N, Matsuda, K, Minegishi, N, Montaner, J, Morris, A P, Muiño, E, Müller-Nurasyid, M, Norrving, B, Ogishima, S, Parati, E A, Reddy Peddareddygari, L, Pedersen, N L, Pera, J, Perola, M, Pezzini, A, Pileggi, S, Rabionet, R, Riba-Llena, I, Ribasés, M, Romero, J R, Roquer, J, Rudd, A G, Sarin, A P, Sarju, R, Sarnowski, C, Sasaki, M, Satizabal, C L, Satoh, M, Sattar, N, Sawada, N, Sibolt, G, Sigurdsson, Á, Smith, A, Sobue, K, Soriano-Tárraga, C, Stanne, T, Colin Stine, O, Stott, D J, Strauch, K, Takai, T, Tanaka, H, Tanno, K, Teumer, A, Tomppo, L, Torres-Aguila, N P, Touze, E, Tsugane, S, Uitterlinden, A G, Valdimarsson, E M, van der Lee, S J, Völzke, H, Wakai, K, Weir, D, Williams, S R, Wolfe, C D A, Wong, Q, Xu, H, Yamaji, T, Sanghera, D K, Melander, O, Jern, C, Strbian, D, Fernandez-Cadenas, I, Longstreth, W T, Rolfs, A, Hata, J, Woo, D, Rosand, J, Pare, G, Hopewell, J C, Saleheen, D, Stefansson, K, Worrall, B B, Kittner, S J, Seshadri, S, Fornage, M, Markus, H S, Howson, J M M, Kamatani, Y, Debette, S & Dichgans, M 2022, ' Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations ', Journal of Thrombosis and Haemostasis, vol. 20, no. 6, pp. 1331-1349 . https://doi.org/10.1111/jth.15698
Temprano-Sagrera, G, Sitlani, C M, Bone, W P, Martin-Bornez, M, Voight, B F, Morrison, A C, Damrauer, S M, de Vries, P S, Smith, N L, Sabater-Lleal, M, Dehghan, A, Heath, A S, Morrison, A C, Reiner, A P, Johnson, A, Richmond, A, Peters, A, van Hylckama Vlieg, A, McKnight, B, Psaty, B M, Hayward, C, Ward-Caviness, C, O’Donnell, C, Chasman, D, Strachan, D P, Tregouet, D A, Mook-Kanamori, D, Gill, D, Thibord, F, Asselbergs, F W, Leebeek, F W G, Rosendaal, F R, Davies, G, Homuth, G, Temprano, G, Campbell, H, Taylor, H A, Bressler, J, Huffman, J E, Rotter, J I, Yao, J, Wilson, J F, Bis, J C, Hahn, J M, Desch, K C, Wiggins, K L, Raffield, L M, Bielak, L F, Yanek, L R, Kleber, M E, Sabater-Lleal, M, Mueller, M, Kavousi, M, Mangino, M, Liu, M, Brown, M R, Conomos, M P, Jhun, M-A, Chen, M-H, de Maat, M P M, Pankratz, N, Smith, N L, Peyser, P A, Elliot, P, de Vries, P S, Wei, P, Wild, P S, Morange, P E, van der Harst, P, Yang, Q, le, N-Q, Marioni, R, Li, R, Damrauer, S M, Cox, S R, Trompet, S, Felix, S B, Völker, U, Tang, W, Koenig, W, Jukema, J W, Guo, X, Lindstrom, S, Wang, L, Smith, E N, Gordon, W, van Hylckama Vlieg, A, de Andrade, M, Brody, J A, Pattee, J W, Haessler, J, Brumpton, B M, Chasman, D I, Suchon, P, Chen, M-H, Turman, C, Germain, M, Wiggins, K L, MacDonald, J, Braekkan, S K, Armasu, S M, Pankratz, N, Jackson, R D, Nielsen, J B, Giulianini, F, Puurunen, M K, Ibrahim, M, Heckbert, S R, Bammler, T K, Frazer, K A, McCauley, B M, Taylor, K, Pankow, J S, Reiner, A P, Gabrielsen, M E, Deleuze, J-F, O’Donnell, C J, Kim, J, McKnight, B, Kraft, P, Hansen, J-B, Rosendaal, F R, Heit, J A, Psaty, B M, Tang, W, Kooperberg, C, Hveem, K, Ridker, P M, Morange, P-E, Johnson, A D, Kabrhel, C, Trégouët, D-A, Smith, N L, Malik, R, Chauhan, G, Traylor, M, Sargurupremraj, M, Okada, Y, Mishra, A, Rutten-Jacobs, L, Giese, A-K, van der Laan, S W, Gretarsdottir, S, Anderson, C D, Chong, M, Adams, H H H, Ago, T, Almgren, P, Amouyel, P, Ay, H, Bartz, T M, Benavente, O R, Bevan, S, Boncoraglio, G B, Brown, R D, Butterworth, A S, Carrera, C, Carty, C L, Chasman, D I, Chen, W-M, Cole, J W, Correa, A, Cotlarciuc, I, Cruchaga, C, Danesh, J, de Bakker, P I W, DeStefano, A L, den Hoed, M, Duan, Q, Engelter, S T, Falcone, G J, Gottesman, R F, Grewal, R P, Gudnason, V, Gustafsson, S, Haessler, J, Harris, T B, Hassan, A, Havulinna, A S, Heckbert, S R, Holliday, E G, Howard, G, Hsu, F-C, Hyacinth, H I, Arfan Ikram, M, Ingelsson, E, Irvin, M R, Jian, X, Jiménez-Conde, J, Johnson, J A, Jukema, J W, Kanai, M, Keene, K L, Kissela, B M, Kleindorfer, D O, Kooperberg, C, Kubo, M, Lange, L A, Langefeld, C D, Langenberg, C, Launer, L J, Lee, J-M, Lemmens, R, Leys, D, Lewis, C M, Lin, W-Y, Lindgren, A G, Lorentzen, E, Magnusson, P K, Maguire, J, Manichaikul, A, McArdle, P F, Meschia, J F, Mitchell, B D, Mosley, T H, Nalls, M A, Ninomiya, T, O’Donnell, M J, Psaty, B M, Pulit, S L, Rannikmäe, K, Reiner, A P, Rexrode, K M, Rice, K, Rich, S S, Ridker, P M, Rost, N S, Rothwell, P M, Rotter, J I, Rundek, T, Sacco, R L, Sakaue, S, Sale, M M, Salomaa, V, Sapkota, B R, Schmidt, R, Schmidt, C O, Schminke, U, Sharma, P, Slowik, A, Sudlow, C L M, Tanislav, C, Tatlisumak, T, Taylor, K D, Thijs, V N S, Thorleifsson, G, Thorsteinsdottir, U, Tiedt, S, Trompet, S, Tzourio, C, van Duijn, C M, Walters, M, Wareham, N J, Wassertheil-Smoller, S, Wilson, J G, Wiggins, K L, Yang, Q, Yusuf, S, Amin, N, Aparicio, H S, Arnett, D K, Attia, J, Beiser, A S, Berr, C, Buring, J E, Bustamante, M, Caso, V, Cheng, Y-C, Hoan Choi, S, Chowhan, A, Cullell, N, Dartigues, J-F, Delavaran, H, Delgado, P, Dörr, M, Engström, G, Ford, I, Gurpreet, W S, Hamsten, A, Heitsch, L, Hozawa, A, Ibanez, L, Ilinca, A, Ingelsson, M, Iwasaki, M, Jackson, R D, Jood, K, Jousilahti, P, Kaffashian, S, Kalra, L, Kamouchi, M, Kitazono, T, Kjartansson, O, Kloss, M, Koudstaal, P J, Krupinski, J, Labovitz, D L, Laurie, C C, Levi, C R, Li, L, Lind, L, Lindgren, C M, Lioutas, V, Mei Liu, Y, Lopez, O L, Makoto, H, Martinez-Majander, N, Matsuda, K, Minegishi, N, Montaner, J, Morris, A P, Muiño, E, Müller-Nurasyid, M, Norrving, B, Ogishima, S, Parati, E A, Reddy Peddareddygari, L, Pedersen, N L, Pera, J, Perola, M, Pezzini, A, Pileggi, S, Rabionet, R, Riba-Llena, I, Ribasés, M, Romero, J R, Roquer, J, Rudd, A G, Sarin, A-P, Sarju, R, Sarnowski, C, Sasaki, M, Satizabal, C L, Satoh, M, Sattar, N, Sawada, N, Sibolt, G, Sigurdsson, Á, Smith, A, Sobue, K, Soriano-Tárraga, C, Stanne, T, Colin Stine, O, Stott, D J, Strauch, K, Takai, T, Tanaka, H, Tanno, K, Teumer, A, Tomppo, L, Torres-Aguila, N P, Touze, E, Tsugane, S, Uitterlinden, A G, Valdimarsson, E M, van der Lee, S J, Völzke, H, Wakai, K, Weir, D, Williams, S R, Wolfe, C D A, Wong, Q, Xu, H, Yamaji, T, Sanghera, D K, Melander, O, Jern, C, Strbian, D, Fernandez-Cadenas, I, Longstreth, W T, Rolfs, A, Hata, J, Woo, D, Rosand, J, Pare, G, Hopewell, J C, Saleheen, D, Stefansson, K, Worrall, B B, Kittner, S J, Seshadri, S, Fornage, M, Markus, H S, Howson, J M M, Kamatani, Y, Debette, S & Dichgans, M 2022, ' Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations ', Journal of Thrombosis and Haemostasis, vol. 20, no. 6, pp. 1331-1349 . https://doi.org/10.1111/jth.15698
Journal of Thrombosis and Haemostasis, 20(6), 1331-1349. Wiley-Blackwell

Background: Multi-phenotype analysis of genetically correlated phenotypes can increase the statistical power to detect loci associated with multiple traits, leading to the discovery of novel loci. This is the first study to date to comprehensively an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b7442423f44fe602d89a89feee11d1
https://hdl.handle.net/20.500.11820/264ae571-0038-4372-9a30-c81b5c9f6905

National implementation of reperfusion for acute ischaemic stroke in England: How should services be configured? A modelling study

Autor: Michael Allen, Kerry Pearn, Gary A Ford, Phil White, Anthony G Rudd, Peter McMeekin, Ken Stein, Martin James

Publikováno v: European stroke journal. 7(1)

Objectives To guide policy when planning thrombolysis (IVT) and thrombectomy (MT) services for acute stroke in England, focussing on the choice between ‘mothership’ (direct conveyance to an MT centre) and ‘drip-and-ship’ (secondary transfer)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd10eb6a0c0c704225ad57471fb474a
https://pubmed.ncbi.nlm.nih.gov/35300255