Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anthony G. Doyle"'
Autor:
Karol Sestak, Jason P. Dufour, David X. Liu, Namita Rout, Xavier Alvarez, James Blanchard, Anne Faldas, David J. Laine, Adam W. Clarke, Anthony G. Doyle
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Overexpression of interleukin-15 (IL-15) is linked with immunopathology of several autoimmune disorders including celiac disease. Here, we utilized an anti-human IL-15 antibody 04H04 (anti-IL-15) to reverse immunopathogenesis of celiac disease. Anti-
Externí odkaz:
https://doaj.org/article/e3305e38e41643ffbdea1933bbfa29f6
Publikováno v:
The Journal of Experimental Medicine
The capacity of activated T cells to alter their cytokine expression profiles after migration into an effector site has not previously been defined. We addressed this issue by paired daughter analysis of a type 1-polarized CD8(+) effector T cell popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ded1a506c61a78f333c77da6be3277
https://doi.org/10.1084/jem.190.8.1081
https://doi.org/10.1084/jem.190.8.1081
Publikováno v:
International Immunology. 11:617-621
RT-PCR was used to examine the expression of IFN-gamma, IL-2, IL-4, IL-5, IL-6 and IL-10 mRNAs by single murine CD4+ T cells activated either in a strongly type 1-polarized mixed lymphocyte reaction (MLR) or in the type 2-polarized response to immuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef8fae163911ac00cdc59eb75caa6d5
https://doi.org/10.1093/intimm/11.4.617
https://doi.org/10.1093/intimm/11.4.617
Publikováno v:
Immunology. 93:341-349
By virtue of their strong bias towards production of interferon-gamma (IFN-gamma), CD8+ T cells have the potential to promote the development of type 1 immune responses. We have previously shown that the CD4+ T-cell response to immunization with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2762e4af220b520200bbf4eb13bf15b9
https://doi.org/10.1046/j.1365-2567.1998.00404.x
https://doi.org/10.1046/j.1365-2567.1998.00404.x
Publikováno v:
Current Opinion in Immunology. 7:24-33
Macrophage molecules involved in adhesion, signalling, secretion and interactions with pathogens and T-helper lymphocytes have been cloned and defined using monoclonal antibodies and genetic disruption. Studies of the regulation of macrophage differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0037f566fd298d0decd11ef5f6c039ee
https://doi.org/10.1016/0952-7915(95)80025-5
https://doi.org/10.1016/0952-7915(95)80025-5
Autor:
Robert D. Gay, Adam W. Clarke, Zehra Elgundi, Teresa Domagala, Raina J. Simpson, Nga B. Le, Anthony G. Doyle, Phil A. Jennings
Publikováno v:
mAbs. 2(6)
We report preclinical data for CEP-37247, the first human framework domain antibody construct to enter the clinic. At approximately 11 - 13kDa, domain antibodies or dAbs are the smallest antibody domain able to demonstrate the antigen-recognition fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820e8678ae308cda18b1b213ffedde15
https://pubmed.ncbi.nlm.nih.gov/20930515
https://pubmed.ncbi.nlm.nih.gov/20930515
Publikováno v:
Doyle, A G, Halliday, W J, Barnett, C J, Dunn, T L & Hume, D A 1992, ' Effect of recombinant human macrophage colony-stimulating factor 1 on immunopathology of experimental brucellosis in mice ', Infection and Immunity, vol. 60, no. 4, pp. 1465-72 .
Scopus-Elsevier
Scopus-Elsevier
Brucella abortus injected into CBA mice replicated primarily in the spleen and liver, reaching a peak bacterial count in both organs about 7 days postinfection. The organism was eliminated from the liver but declined to a chronic phase in the spleen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70c37b76bf911c7f68c9d24ba6c35f9
https://europepmc.org/articles/PMC257019/
https://europepmc.org/articles/PMC257019/
