Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anthony G Doran"'
Autor:
Rebecca L Allchin, Michael E Kelly, Sami Mamand, Anthony G Doran, Thomas Keane, Matthew J Ahearne, Simon D Wagner
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215765 (2019)
Recent analyses of the genetics of peripheral T-cell lymphoma (PTCL) have shown that a large proportion of cases are derived from normal follicular helper (Tfh) T-cells. The sanroque mouse strain bears a mutation that increases Tfh cell number and he
Externí odkaz:
https://doaj.org/article/6fb98bd0807a4371ababb29800aa0c00
Autor:
Andrew P. Morgan, John P. Didion, Anthony G. Doran, James M. Holt, Leonard McMillan, Thomas M. Keane, Fernando Pardo-Manuel de Villena
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 12, Pp 4211-4216 (2016)
Wild-derived mouse inbred strains are becoming increasingly popular for complex traits analysis, evolutionary studies, and systems genetics. Here, we report the whole-genome sequencing of two wild-derived mouse inbred strains, LEWES/EiJ and ZALENDE/E
Externí odkaz:
https://doaj.org/article/442e37b90d304a4ba8258bbca0866b41
Autor:
Craig L. Franklin, Lloyd W. Sumner, Jacob E. Moskowitz, Marcia L. Hart, Susheel Bhanu Busi, James M. Amos-Landgraf, Anthony G. Doran, Zhentian Lei, Thomas M. Keane
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-16 (2020)
BMC Cancer
BMC Cancer
Background Colorectal cancer (CRC) is a multifactorial disease resulting from both genetic predisposition and environmental factors including the gut microbiota (GM), but deciphering the influence of genetic variants, environmental variables, and int
Autor:
Leonard McMillan, John P. Didion, Thomas M. Keane, Andrew P. Morgan, Anthony G. Doran, Fernando Pardo-Manuel de Villena, James Holt
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 12, Pp 4211-4216 (2016)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Wild-derived mouse inbred strains are becoming increasingly popular for complex traits analysis, evolutionary studies, and systems genetics. Here, we report the whole-genome sequencing of two wild-derived mouse inbred strains, LEWES/EiJ and ZALENDE/E
Autor:
Kerstin Howe, Thomas M. Keane, Paul Flicek, David Thybert, Bronwen Aken, David Martín-Gálvez, Golbahar Yazdanifar, Christine Feig, Cristina Sisu, Duncan T. Odom, Son Pham, Stefanie Nachtweide, Laura Clarke, Ian Streeter, Carla Cummins, Varshith Chakrapani, Lilue Jingtao, Cock van Oosterhout, Ian T. Fiddes, Alvis Brazma, David J. Adams, William Chow, Frédéric Veyrunes, Maša Roller, Mikhail Kolmogorov, Christina M. Laukaitis, Ambre Aurore Josselin, Matthew Howell, Fergal J. Martin, Klara Stefflova, Benedict Paten, Mario Stanke, Matthieu Muffato, Mark Gerstein, Leo Goodstadt, Fengtang Yang, Michael A. Quail, Anthony G. Doran, Václav Janoušek, Ben J. Ward, Sarah Aldridge, Amonida Zadissa, Fabio C. P. Navarro, Robert C. Karn, Matthew Dunn, Wasiu Akanni
Publikováno v:
Genome Research
Genome Research, Cold Spring Harbor Laboratory Press, 2018, 28 (4), pp.448-459. ⟨10.1101/gr.234096.117⟩
Genome Research, 2018, 28 (4), pp.448-459. ⟨10.1101/gr.234096.117⟩
Genome Research, Cold Spring Harbor Laboratory Press, 2018, 28 (4), pp.448-459. ⟨10.1101/gr.234096.117⟩
Genome Research, 2018, 28 (4), pp.448-459. ⟨10.1101/gr.234096.117⟩
Understanding the mechanisms driving lineage-specific evolution in both primates and rodents has been hindered by the lack of sister clades with a similar phylogenetic structure having high-quality genome assemblies. Here, we have created chromosome-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609fd04d943fa94511f96a605cf6355f
https://www.repository.cam.ac.uk/handle/1810/279898
https://www.repository.cam.ac.uk/handle/1810/279898
Autor:
Dent Earl, Monica Abrudan, Benedict Paten, Adam Frankish, Lesley Shirley, Cristina Sisu, Ian T. Fiddes, Mark Gerstein, James G. R. Gilbert, Mark G. Thomas, Anne Czechanski, Duncan T. Odom, William Chow, Stephan C. Collins, Clayton E. Mathews, Mark Diekhans, Ruth Bennett, Jane E. Loveland, David J. Adams, Jingtao Lilue, Beiyuan Fu, Dirk-Dominic Dolle, Fengtang Yang, Laura G. Reinholdt, Glen Threadgold, Anne C. Ferguson-Smith, Jonathan Wood, Kim Wong, Leo Goodstadt, Paul R. Muir, Thomas M. Keane, Phan Sk, Jonathan Flint, Naomi R Park, Richard Mott, Joel Armstrong, Thybert D, Jen Harrow, Petr Danecek, Marcela K. Sjoberg-Herrera, Sarah Pelan, Anthony G. Doran, Kerstin Howe, Charles A. Steward, Mario Stanke, Binnaz Yalcin, Joanna Collins, Lelliott C, Matthew Dunn, Fabio C. P. Navarro, Michael A. Quail, Paul Flicek, James Torrance, Richard Durbin, Köenig S, Lars Romoth, Mikhail Kolmogorov
The most commonly employed mammalian model organism is the laboratory mouse. A wide variety of genetically diverse inbred mouse strains, representing distinct physiological states, disease susceptibilities, and biological mechanisms have been develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71500bb485bfaa2d484c7df8a7e4cb83
https://doi.org/10.1101/235838
https://doi.org/10.1101/235838
Autor:
Leo Goodstadt, Mark Gerstein, Mark G. Thomas, Jingtao Lilue, Glen Threadgold, Fengtang Yang, Sarah Pelan, Jane E. Loveland, Kim Wong, Fabio C. P. Navarro, Jennifer Harrow, Ruth Bennett, Richard Durbin, Dent Earl, Monica Abrudan, Mario Stanke, David J. Adams, Adam Frankish, Son Pham, Anne Czechanski, Charles A. Steward, Jonathan Flint, Beiyuan Fu, Ian T. Fiddes, William Chow, Duncan T. Odom, Marcela K. Sjoberg-Herrera, Naomi Park, Paul Flicek, Anne C. Ferguson-Smith, James G. R. Gilbert, Lelliott C, Mikhail Kolmogorov, Mark Diekhans, Laura G. Reinholdt, Stefanie Nachtweide, Cristina Sisu, Thomas M. Keane, James Torrance, Richard Mott, Benedict Paten, Petr Danecek, Dirk-Dominik Dolle, Paul R. Muir, Ximena Ibarra-Soria, Stephan C. Collins, Binnaz Yalcin, Darren W. Logan, Lars Romoth, Matthew Dunn, Lesley Shirley, Kerstin Howe, David Thybert, Michael A. Quail, Clayton E. Mathews, Jonathan Wood, Anthony G. Doran, Joanna Collins, Joel Armstrong
Publikováno v:
Nature Genetics
Nature Genetics, Nature Publishing Group, 2018, 50 (11), pp.1574-1583. ⟨10.1038/s41588-018-0223-8⟩
Nature Genetics, 2018, 50 (11), pp.1574-1583. ⟨10.1038/s41588-018-0223-8⟩
Nature genetics
Nature Genetics, Nature Publishing Group, 2018, 50 (11), pp.1574-1583. ⟨10.1038/s41588-018-0223-8⟩
Nature Genetics, 2018, 50 (11), pp.1574-1583. ⟨10.1038/s41588-018-0223-8⟩
Nature genetics
We report full-length draft de novo genome assemblies for 16 widely used inbred mouse strains and find extensive strain-specific haplotype variation. We identify and characterize 2,567 regions on the current mouse reference genome exhibiting the grea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc230ec19054ff114163ced9d381919
http://bura.brunel.ac.uk/handle/2438/16930
http://bura.brunel.ac.uk/handle/2438/16930
Autor:
Anthony G. Doran, Václav Janoušek, David Martín-Gálvez, Robert C. Karn, Fengtang Yang, Fergal J. Martin, Klara Stefflova, Mario Stanke, Duncan T. Odom, William Chow, Ian T. Fiddes, Paul Flicek, Mark Gerstein, Golbahar Yazdanifar, Christine Feig, Ian Streeter, Ben J. Ward, Wasiu Akanni, Varshith Chakrapani, Cock van Oosterhout, David Thybert, Sarah Aldridge, Amonida Zadissa, Laura Clarke, David J. Adams, Christina M. Laukaitis, Alvis Brazma, Maša Roller, Thomas M. Keane, Michael A. Quail, Lilue Jingtao, Cristina Sisu, Carla Cummins, Bronwen Aken, Matthieu Muffato, Leo Goodstadt, Frédéric Veyrunes, Matthew Howell, Fabio C. P. Navarro, Son Pham, Mikhail Kolmogorov, Matthew Dunn, Ambre Aurore Josselin, Benedict Paten, Kerstin Howe
Understanding the mechanisms driving lineage-specific evolution in both primates and rodents has been hindered by the lack of sister clades with a similar phylogenetic structure having high-quality genome assemblies. Here, we have created chromosome-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2986e9e3db033fccd34237ec60a2b55
https://doi.org/10.1101/158659
https://doi.org/10.1101/158659
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 26(9-10)
The Mouse Genomes Project was initiated in 2009 with the goal of using next-generation sequencing technologies to catalogue molecular variation in the common laboratory mouse strains, and a selected set of wild-derived inbred strains. The initial seq
Publikováno v:
BMC Bioinformatics, Vol 14, Iss 1, p 45 (2013)
BMC Bioinformatics
BMC Bioinformatics
peer-reviewed peer-reviewed Background: Single nucleotide polymorphisms (SNPs) are the most abundant genetic variant found in vertebrates and invertebrates. SNP discovery has become a highly automated, robust and relatively inexpensive process allowi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe93bddba6fb7324bb091a4113c1dd6
http://hdl.handle.net/11019/402
http://hdl.handle.net/11019/402