Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anthony Fernandez‐Castaneda"'
Autor:
Hyunjung Min, Li Xu, Roberta Parrott, Christopher Overall, Melina Lillich, Norin Meadows, Anthony Fernandez‐Castaneda, Alban Gaultier, Joanne Kurtzberg, Anthony Filiano
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss S1, Pp S2-S2 (2020)
Externí odkaz:
https://doaj.org/article/fa94f62cc15a40519d70b4e8acf2d6cd
Autor:
Anthony J. Filiano, Hyunjung Min, Roberta E. Parrott, Rishi R. Rampersad, N. Meadows, Alban Gaultier, Emily M. Rabjohns, Christopher C. Overall, Joanne Kurtzberg, Anthony Fernandez-Castaneda, Li Xu, Teresa K. Tarrant, M. Lillich
Publikováno v:
Stem Cells. 39:115-128
Mesenchymal stromal cells (MSCs) are widely used in clinical trials because of their ability to modulate inflammation. The success of MSCs has been variable over 25 years, most likely due to an incomplete understanding of their mechanism. After MSCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d483867c8ade6b052f58779c7e71615d
https://doi.org/10.1002/stem.3292
https://doi.org/10.1002/stem.3292
Autor:
Charles Spivey, Scott M. Seki, Alban Gaultier, Vlad Serbulea, Anthony Fernandez-Castaneda, Nikolas William Hayes, Rebecca L. McCloud, Ku-Lung Hsu, Lelisa Gemta, Dorian A. Rosen, Sarah C. Nanziri, Kacper Posyniak, Timothy N. J. Bullock, Rebecca M. Beiter
Publikováno v:
Sci Signal
Immunometabolism
Immunometabolism
Small molecules that promote the metabolic activity of the pyruvate kinase isoform PKM2, such as TEPP-46 and DASA-58, limit tumorigenesis and inflammation. To understand how these compounds alter T cell function, we assessed their therapeutic activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8aee33d056a8440d07dfdc277416f4
https://doi.org/10.1126/scisignal.aay9217
https://doi.org/10.1126/scisignal.aay9217
Autor:
Scott M. Seki, Delaney Liskey, Rebecca M. Beiter, Emily Farber, Megan S Chappell, Christopher C. Overall, David M. Johanson, Suna Onengut-Gumuscu, Jeffrey L. Dupree, Dorian A. Rosen, Anthony Fernandez-Castaneda, Alban Gaultier
Publikováno v:
Acta Neuropathol
Oligodendrocyte progenitor cells (OPCs) account for about 5% of total brain and spinal cord cells, giving rise to myelinating oligodendrocytes that provide electrical insulation to neurons of the CNS. OPCs have also recently been shown to regulate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b3c66f2f8d974c5a97fbcb1d18bff2
https://pubmed.ncbi.nlm.nih.gov/31552482
https://pubmed.ncbi.nlm.nih.gov/31552482
Autor:
Ku-Lung Hsu, Kacper Posyniak, Timothy N. J. Bullock, Charles Spivey, Rebecca M. Beiter, Scott M. Seki, Rebecca L. McCloud, Nikolas William Hayes, Lelisa Gemta, Dorian A. Rosen, Alban Gaultier, Anthony Fernandez-Castaneda
Publikováno v:
SSRN Electronic Journal.
T cells play crucial, and perhaps initiating roles in autoimmune diseases like Multiple Sclerosis (MS). Elucidating the mechanisms that regulate inflammatory T cell responses could reveal novel means of modulation of their pathological role. Small mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1952bb5d6157a45296fb1b1082877e6
https://doi.org/10.2139/ssrn.3363732
https://doi.org/10.2139/ssrn.3363732
Autor:
Rebecca M. Beiter, Scott M. Seki, Alban Gaultier, Anthony Fernandez-Castaneda, Dorian A. Rosen, Judith A. Woodfolk, Jacob D. Eccles
Publikováno v:
Science translational medicine. 11(478)
Sepsis is an often-deadly complication of infection in which systemic inflammation damages the vasculature, leading to tissue hypoperfusion and multiple organ failure. Currently, the standard of care for sepsis is predominantly supportive, with few t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c11e1c3378dbaf24bc254e885749f7
https://pubmed.ncbi.nlm.nih.gov/30918112
https://pubmed.ncbi.nlm.nih.gov/30918112
Oligodendrocyte progenitor cells (OPCs) are the often-overlooked fourth glial cell type in the central nervous system (CNS), comprising about 5% of the CNS. For a long time, our vision of OPC function was limited to the generation of mature oligodend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647231be7c872011ceaa639f19bc1566
https://europepmc.org/articles/PMC4940337/
https://europepmc.org/articles/PMC4940337/
Autor:
Courtney R. Rivet-Noor, Andrea R. Merchak, Sihan Li, Rebecca M. Beiter, Sangwoo Lee, Jalon Aaron Thomas, Anthony Fernández-Castañeda, Jung-Bum Shin, Alban Gaultier
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Current treatments for major depressive disorder are limited to neuropharmacological approaches and are ineffective for large numbers of patients. Recently, alternative means have been explored to understand the etiology of depression. Speci
Externí odkaz:
https://doaj.org/article/f8f17340c1414793a86253f65a3000ae
Autor:
Roman J. Giger, Steven L. Gonias, Travis L. Dickendesher, Travis L. Stiles, Alban Gaultier, Anthony Fernandez-Castaneda, Elisabetta Mantuano
Summary In the injured adult mammalian central nervous system (CNS), products are generated that inhibit neuronal sprouting and regeneration. In recent years, most attention has focused on the myelin-associated inhibitory proteins (MAIs) Nogo-A, OMgp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7ad945baa726d9f06c0fc2b0596aa3
http://hdl.handle.net/11573/769666
http://hdl.handle.net/11573/769666
Autor:
Jingjing Zheng, Johannes Vogt, Frauke Zipp, Igor Smirnov, John R. Lukens, Ralf Gold, Thirumala-Devi Kanneganti, Greta Gölz, Sachin P. Gadani, Volker Siffrin, Francesco Boato, Christina F. Vogelaar, Ali Radjavi, Thomas Kammertöns, Daniel Hechler, James T. Walsh, Jonathan Kipnis, Alban Gaultier, Anthony Fernandez-Castaneda, Karen Rosenberger, Robert Nitsch, Sven Hendrix
Publikováno v:
Journal of Clinical Investigation. 125:2547-2547
A body of experimental evidence suggests that T cells mediate neuroprotection following CNS injury; however, the antigen specificity of these T cells and how they mediate neuroprotection are unknown. Here, we have provided evidence that T cell-mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0ced98ef727fb1d2e70021f32f6e12
https://doi.org/10.1172/jci82458
https://doi.org/10.1172/jci82458