Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anthony F. Nastase"'
Autor:
Aaron M. Bender, Thomas J Fernandez, John R. Traynor, Emily M. Jutkiewicz, Henry I. Mosberg, Nicholas W. Griggs, Jessica P. Anand, Anthony F. Nastase, Deanna Montgomery
Publikováno v:
Journal of Medicinal Chemistry. 62:4193-4203
Short-acting μ-opioid receptor (MOR) agonists have long been used for the treatment of severe, breakthrough pain. However, selective MOR agonists including fentanyl and morphine derivatives are limited clinically due to high risks of dependence, tol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfc327b5a0e52c3aca3e632834c3510
https://doi.org/10.1021/acs.jmedchem.9b00378
https://doi.org/10.1021/acs.jmedchem.9b00378
Autor:
Emily M. Jutkiewicz, Nicholas W. Griggs, Henry I. Mosberg, Jessica P. Anand, Anthony F. Nastase, Deanna Montgomery, Kelsey E Kochan, John R. Traynor
Publikováno v:
British Journal of Pharmacology. 175:2013-2027
BACKGROUND AND PURPOSE Agonists at μ-opioid receptors (μ-receptors) are used for pain management but produce adverse effects including tolerance, dependence and euphoria. The co-administration of a μ-receptor agonist with a δ-opioid receptor (δ-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5ca42222ac9170fc7afdba2255cc86f
https://doi.org/10.1111/bph.14148
https://doi.org/10.1111/bph.14148
Autor:
Anthony F. Nastase, Jessica P. Anand, Tyler J. Trask, Henry I. Mosberg, Emily M. Jutkiewicz, Thomas J Fernandez, Nicholas W. Griggs, John R. Traynor, Aubrie A. Harland
Publikováno v:
ACS Chem Neurosci
The use of opioids for the treatment of pain, while largely effective, is limited by detrimental side effects including analgesic tolerance, physical dependence, and euphoria, which may lead to opioid abuse. Studies have shown that compounds with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2aa9cd90a3cb78894dd62220fff74cb
https://doi.org/10.1021/acschemneuro.8b00139
https://doi.org/10.1021/acschemneuro.8b00139
Autor:
Nicholas W. Griggs, Thomas J Fernandez, John R. Traynor, Anthony F. Nastase, Jessica P. Anand, Emily J. Jutkiewicz, Henry I. Mosberg
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec105a736b1b6aa13a618c2bfccdae35
https://doi.org/10.1096/fasebj.2018.32.1_supplement.689.6
https://doi.org/10.1096/fasebj.2018.32.1_supplement.689.6
Autor:
Jessica P, Anand, Kelsey E, Kochan, Anthony F, Nastase, Deanna, Montgomery, Nicholas W, Griggs, John R, Traynor, Henry I, Mosberg, Emily M, Jutkiewicz
Publikováno v:
British journal of pharmacology. 175(11)
BACKGROUND AND PURPOSE: Agonists at μ‐opioid receptors (μ‐receptors) are used for pain management but produce adverse effects including tolerance, dependence and euphoria. The co‐administration of a μ‐receptor agonist with a δ‐opioid re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28125a02c42cbdd344b119d69c09dd46
https://pubmed.ncbi.nlm.nih.gov/29352503
https://pubmed.ncbi.nlm.nih.gov/29352503
Autor:
Donald B. Boyd, Anthony F. Nastase
Publikováno v:
Journal of chemical information and modeling. 52(12)
Beta-site amyloid precursor protein cleaving enzyme-1 (BACE1) is a target of interest for treating patients with Alzheimer's disease (AD). Inhibition of BACE1 may prevent amyloid-ß (Aß) plaque formation and the development or progression of Alzheim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0deca30c38658fa5f59755e28f39c1a2
https://pubmed.ncbi.nlm.nih.gov/23198745
https://pubmed.ncbi.nlm.nih.gov/23198745