Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anthony E. Theobald"'
Publikováno v:
Journal of Medicinal Chemistry. 45:631-639
A range of novel 3-hydroxypyridin-4-ones with different R(2) substitutents has been synthesized for the investigation of the structure-activity relationship between the chemical nature of the ligand and the inhibitory activity of the iron-containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d629d1dec7e06b70184c362e7bb81db
https://doi.org/10.1021/jm010817i
https://doi.org/10.1021/jm010817i
Autor:
M. Lis-Balchin, J.Robin S. Hoult, Anthony E. Theobald, Nicolette S. L. Perry, Peter J. Houghton, Stuart Milligan, Julia Sampson, Elaine K. Perry, Peter Jenner, Patricia Evans, Stephen L. Hart
Publikováno v:
Journal of Pharmacy and Pharmacology. 53:1347-1356
Salvia lavandulaefolia Vahl. (Spanish sage) essential oil and individual monoterpenoid constituents have been shown to inhibit the enzyme acetylcholinesterase in-vitro and in-vivo. This activity is relevant to the treatment of Alzheimer's disease, si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8078de610182ca4e7892dcc0683aad0
https://doi.org/10.1211/0022357011777846
https://doi.org/10.1211/0022357011777846
Publikováno v:
Biochemical Pharmacology. 61:285-290
1 3-Hydroxypyridin-4-ones are currently one of the main candidates for the development of orally active iron chelators. Small bidentate ligands tend to inhibit iron-containing metalloenzymes and therefore can cause undesirable side effects. A range o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e12217e3e7ca6e140364999c805a430
https://doi.org/10.1016/s0006-2952(00)00551-7
https://doi.org/10.1016/s0006-2952(00)00551-7
Publikováno v:
The Journal of pharmacy and pharmacology. 52(7)
Sage (Salvia spp) is reputed in European herbal encyclopaedias to enhance memory, and current memory-enhancing/anti-dementia drugs are based on enhancing cholinergic activity by inhibiting cholinesterase. In this study the effects of Salvia lavandula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5af9925839edb9697229d9071a76de
https://pubmed.ncbi.nlm.nih.gov/10933142
https://pubmed.ncbi.nlm.nih.gov/10933142
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 10(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130ec3e0e66ead5ff01c8ee58d52f84c
https://pubmed.ncbi.nlm.nih.gov/1286135
https://pubmed.ncbi.nlm.nih.gov/1286135
Publikováno v:
The Journal of pharmacy and pharmacology. 30(7)
Using three brands of multiple-scored levodopa tablets B.P. (500 mg) and one brand of sulphamethoxypyridazine tablets B.P. (500 mg) the weight and content uniformity of the subdivisions has been examined. It is shown that quartering of such tablets c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a49fb362997bc99f0d9dab087b95ee
https://pubmed.ncbi.nlm.nih.gov/27603
https://pubmed.ncbi.nlm.nih.gov/27603