Zobrazeno 1 - 10
of 527
pro vyhledávání: '"Anthony E. Pegg"'
Autor:
André S. Bachmann, Anthony E. Pegg, Ivonne Gamper, Christopher J. Wallick, Craig C. Coleman, David J. Feith, Tamas Borsics, Dana-Lynn T. Koomoa
S-adenosylmethionine decarboxylase (AdoMetDC) is an essential enzyme of polyamine (PA) biosynthesis, and both AdoMetDC and PA levels are often up-regulated in cancer cells. The second-generation inhibitor SAM486A inhibits AdoMetDC enzyme activity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce8a5ab05ca9a6df6c1da8c2fcccff5
https://doi.org/10.1158/1535-7163.c.6531927.v1
https://doi.org/10.1158/1535-7163.c.6531927.v1
Autor:
André S. Bachmann, Anthony E. Pegg, Ivonne Gamper, Christopher J. Wallick, Craig C. Coleman, David J. Feith, Tamas Borsics, Dana-Lynn T. Koomoa
Supplementary Table 1 from Inhibition of S-adenosylmethionine decarboxylase by inhibitor SAM486A connects polyamine metabolism with p53-Mdm2-Akt/protein kinase B regulation and apoptosis in neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5913392aa685cba54676327fb3f19b8f
https://doi.org/10.1158/1535-7163.22485426
https://doi.org/10.1158/1535-7163.22485426
Autor:
André S. Bachmann, Anthony E. Pegg, Ivonne Gamper, Christopher J. Wallick, Craig C. Coleman, David J. Feith, Tamas Borsics, Dana-Lynn T. Koomoa
Supplementary Figure 2 from Inhibition of S-adenosylmethionine decarboxylase by inhibitor SAM486A connects polyamine metabolism with p53-Mdm2-Akt/protein kinase B regulation and apoptosis in neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dc5847ba1cc7ccad0c1346a43bb023
https://doi.org/10.1158/1535-7163.22485429
https://doi.org/10.1158/1535-7163.22485429
Autor:
André S. Bachmann, Anthony E. Pegg, Ivonne Gamper, Christopher J. Wallick, Craig C. Coleman, David J. Feith, Tamas Borsics, Dana-Lynn T. Koomoa
Supplementary Figure 1 from Inhibition of S-adenosylmethionine decarboxylase by inhibitor SAM486A connects polyamine metabolism with p53-Mdm2-Akt/protein kinase B regulation and apoptosis in neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23abefeb38a9046b9e91159f5375132
https://doi.org/10.1158/1535-7163.22485432.v1
https://doi.org/10.1158/1535-7163.22485432.v1
Data from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Germ-line mutations in BRCA2 have been linked to early-onset familial breast cancer. BRCA2 is known to play a key role in repairing double-strand breaks. Here, we describe the involvement of BRCA2 in O6-alkylguanine DNA alkyltransferase (AGT)–media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb6619d85d3a89b3dbac5caabed9e9d
https://doi.org/10.1158/0008-5472.c.6498177.v1
https://doi.org/10.1158/0008-5472.c.6498177.v1
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Supplementary Figure 1 from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3f26f9072f886a6cbb3b25f229e501
https://doi.org/10.1158/0008-5472.22376379
https://doi.org/10.1158/0008-5472.22376379
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Supplementary Table 1 from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9b1df510650c2a3ff5b4b9f615f8c2
https://doi.org/10.1158/0008-5472.22376364.v1
https://doi.org/10.1158/0008-5472.22376364.v1
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Supplementary Information from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d878b4204495768a4849184643ac163
https://doi.org/10.1158/0008-5472.22376367.v1
https://doi.org/10.1158/0008-5472.22376367.v1
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Supplementary Figure 2 from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19cf58036a621f2441f76708cb8bc35b
https://doi.org/10.1158/0008-5472.22376376
https://doi.org/10.1158/0008-5472.22376376
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Supplementary Figure 3 from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ae02a570635bb7e4b91c0379a053c1
https://doi.org/10.1158/0008-5472.22376373
https://doi.org/10.1158/0008-5472.22376373