Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anthony Drier"'
Autor:
Matthew I. Milowsky, Young E. Whang, Marc A. Bjurlin, Allison M. Deal, Chelsea K. Osterman, Hung-Jui Tan, Anthony Drier, Eric Wallen, Blaine Brower, Michael R. Harrison, William Y. Kim, Tracy L. Rose, Daniel J. George, Matthew E. Nielsen, Tian Zhang, Hillary M. Heiling, Michael Woods, Angela B. Smith, Sundhar Ramalingam, Mary W. Dunn
Publikováno v:
J Clin Oncol
PURPOSE To evaluate the safety and efficacy of gemcitabine and cisplatin in combination with the immune checkpoint inhibitor pembrolizumab as neoadjuvant therapy before radical cystectomy (RC) in muscle-invasive bladder cancer. METHODS Patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04aeb98f69ab5cc743942d86345f2de
https://europepmc.org/articles/PMC8478388/
https://europepmc.org/articles/PMC8478388/
Autor:
Jordan Kardos, Ethan Basch, David D. Chism, Ajjai Alva, Tracy L. Rose, Mary W. Dunn, Susan J. Maygarden, Paul A. Godley, Anthony Drier, Young E. Whang, Matthew I. Milowsky, William Y. Kim, Allison M. Deal
Publikováno v:
British Journal of Cancer
Background The majority of urothelial cancers (UC) harbor alterations in retinoblastoma (Rb) pathway genes that can lead to loss of Rb tumour suppressor function. Palbociclib is an oral, selective inhibitor of CDK 4/6 that restores Rb function and pr
Autor:
Tracy L Rose, Michael Roger Harrison, Allison Mary Deal, Chelsea K. Osterman, Sundhar Ramalingam, Young E. Whang, Blaine Y Brower, Marc Bjurlin, Angela B. Smith, Matthew E. Nielsen, Hung-Jui Tan, Eric M. Wallen, Daniel J. George, Tian Zhang, Anthony Drier, William Y. Kim, Matthew I. Milowsky
Publikováno v:
Journal of Clinical Oncology. 39:396-396
396 Background: Cisplatin-based neoadjuvant chemotherapy is standard of care in MIBC with improved pathologic response and overall survival (OS) compared to RC alone. Pembrolizumab (pembro) is active in high-risk non-muscle invasive and metastatic bl
Autor:
Daniel J. Crona, Emily Fox Bell, Margaret R Sketch, Young E. Whang, Anthony Drier, Tracy L. Rose, Amy Garrett, Paul A. Godley, Khalis Mitchell, Jing Daisy Zhu, Mary W. Dunn, Scott A. Tomlins, Elizabeth Claire Dees, Matthew I. Milowsky, Ethan Basch
Publikováno v:
Journal of Clinical Oncology. 37:305-305
305 Background: The Strata trial (NCT03061305) is a multi-institutional precision oncology collaboration structured as an observational protocol that aims to match patients to genomically-guided therapies. Methods: Selected University of North Caroli
Autor:
Michele C. Hayward, Sara E. Wobker, Matthew I. Milowsky, Daniel J. Crona, Blaine Brower, Gregory Mayhew, Young E. Whang, Patrick Eulitt, Ashley H. Salazar, Yoichiro Shibata, Katrina A. McGinty, Tracy L. Rose, Joshua M. Uronis, Mary W. Dunn, Anthony Drier, William Y. Kim
Publikováno v:
Journal of Clinical Oncology. 37:458-458
458 Background: Fibroblast growth factor receptor (FGFR) inhibitors are a promising new targeted therapy for patients with metastatic urothelial cancer (UC) and FGFR alterations. FGFR-altered tumors are more likely to be of the luminal molecular subt
Autor:
Gopa Iyer, Harry W. Herr, Jamie Riches, S. Machele Donat, Jonathan E. Rosenberg, Dean F. Bajorin, Hikmat Al-Ahmadie, Guido Dalbagni, Bernard H. Bochner, Ashley Marie Regazzi, Michael Woods, Brooke Elizabeth Kania, Anthony Drier, William C. Huang, Asia S. McCoy, Tracy Lynn Rose, Arjun Vasant Balar, Mariel Elena Boyd, Matthew I. Milowsky, Irina Ostrovnaya
Publikováno v:
Journal of Clinical Oncology. 34:5011-5011
5011Background: Individual DDR genetic alterations have been reported to be predictive for neo chemotherapy response in UC. We sought to identify whether alterations in a DDR gene set correlate wit...