Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Anthony DiNatale"'
Autor:
Anthony DiNatale, Asurayya Worrede, Waleed Iqbal, Michael Marchioli, Allison Toth, Martin Sjöström, Xiaolin Zhu, Eva Corey, Felix Y. Feng, Wanding Zhou, Alessandro Fatatis
Publikováno v:
Cancer Res Commun
We report the inverse association between the expression of androgen receptor (AR) and IL1β in a cohort of patients with metastatic castration-resistant prostate cancer. We also discovered that AR represses the IL1β gene by binding an androgen resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacb0f69e03eb0c1488af806bbf0b076
https://doi.org/10.1158/2767-9764.crc-22-0262
https://doi.org/10.1158/2767-9764.crc-22-0262
Autor:
Alessandro Fatatis, Olimpia Meucci, Massimo Cristofanilli, Qiang Zhang, Ramanpreet Kaur, Anthony DiNatale, Fei Shen, Asurayya Worrede-Mahdi, Chen Qian
IC50 for the FX-68 compound.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e235e24e9a34410105e0fbe9a45947
https://doi.org/10.1158/1541-7786.22512157.v1
https://doi.org/10.1158/1541-7786.22512157.v1
Autor:
Alessandro Fatatis, Olimpia Meucci, Massimo Cristofanilli, Qiang Zhang, Ramanpreet Kaur, Anthony DiNatale, Fei Shen, Asurayya Worrede-Mahdi, Chen Qian
Circulating tumor cells (CTCs) are commonly detected in the systemic blood of patients with cancer with metastatic tumors. However, the mechanisms controlling the viability of cancer cells in blood and length of time spent in circulation, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6016186bcac8418e7f68c4a4b1e7134
https://doi.org/10.1158/1541-7786.c.6540148.v1
https://doi.org/10.1158/1541-7786.c.6540148.v1
Autor:
Anthony DiNatale, Ramanpreet Kaur, Chen Qian, Jieyi Zhang, Michael Marchioli, Darin Ipe, Maria Castelli, Chris M. McNair, Gaurav Kumar, Olimpia Meucci, Alessandro Fatatis
Publikováno v:
Oncogene
Metastasis-initiating cells (MICs) display stem cell-like features, cause metastatic recurrences and defy chemotherapy, which leads to patients’ demise. Here we show that prostate and breast cancer patients harbor contingents of tumor cells with hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c2970e5e1b58474adda6f3dc2d996c
https://doi.org/10.1038/s41388-021-02174-w
https://doi.org/10.1038/s41388-021-02174-w
Autor:
Anthony, DiNatale, Maria Sofia, Castelli, Bradley, Nash, Olimpia, Meucci, Alessandro, Fatatis
Publikováno v:
Journal of Cancer. 13:3160-3176
Tumor-initiating cells (TICs) are a rare sub-population of cells within the bulk of a tumor that are major contributors to tumor initiation, metastasis, and chemoresistance. TICs have a stem-cell-like phenotype that is dictated by the expression of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8321bbe4b573ce2853faf3ef9c33a4e2
https://doi.org/10.7150/jca.72331
https://doi.org/10.7150/jca.72331
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
We report the inverse association between the expression of androgen receptor (AR) and IL1β in a cohort of patients with metastatic castration-resistant prostate cancer. We also discovered that AR represses the IL1β gene by binding an androgen resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1180c9fd179715198a0abbf3b04c86de
https://doi.org/10.1158/2767-9764.c.6487576
https://doi.org/10.1158/2767-9764.c.6487576
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
Expression of CMV-AR and TRE-AR constructs in PC3-ML cells, confirmed at the transcript level for both (a) and at the protein level for the TRE-AR following addition of doxycycline to the culture medium (b).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee84f238b7723f869523c8c0bf3af55
https://doi.org/10.1158/2767-9764.22361305
https://doi.org/10.1158/2767-9764.22361305
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
PC3-ML cells show no difference in luciferase activity between the wild-type promoter and the AREΔ IL-1β promoter, in which the ARE half-site located at -576 was removed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723e0c0279caaba2a83bbf9dd0af546c
https://doi.org/10.1158/2767-9764.22361299
https://doi.org/10.1158/2767-9764.22361299
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
PC3-ML cells transduced with an inducible AR-overexpression construct showed strong mitigation of IL-1β expression (a) and secretion (b), as compared to both wild type, non-transduced cells and transduced cells without doxycycline exposure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bb3884e2ed311e443924cc61e25c64
https://doi.org/10.1158/2767-9764.22361302
https://doi.org/10.1158/2767-9764.22361302
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
Primer sequences used for ChIP assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80daa869014a1d8722bd729da127d9eb
https://doi.org/10.1158/2767-9764.22361296.v1
https://doi.org/10.1158/2767-9764.22361296.v1