Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anthony David Baxter"'
A novel arylsilane based linker has been prepared for the solid phase synthesis of small molecule combinatorial libraries. Efficient cleavage is achieved using TFA via anchimerically assisted protiodesilylation to yield aromatic products possessing n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1806b10269d7033db07fcc045ee8f0c9
https://ora.ox.ac.uk/objects/uuid:b91b556d-3a54-48cf-aeef-338ae52050a8
https://ora.ox.ac.uk/objects/uuid:b91b556d-3a54-48cf-aeef-338ae52050a8
Autor:
Stephen G. Davies, John Mykytiuk, Jason Eames, Steven D. Bull, Anthony David Baxter, Sean P. Bew
The bis-enolate derived from 1,3-di-isobutyryl- trans -4,5-tetramethylene-imidazolidin-2-one 8 is unstable and deacylates to afford dianion 11 which can be regioselectively alkylated to afford unsymmetric cyclic urea 17 in good yield. Subsequent deac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d7352b124a19ffe7eaf45e57922603
https://ora.ox.ac.uk/objects/uuid:8aea37fd-7579-4843-addf-a8d5672c2879
https://ora.ox.ac.uk/objects/uuid:8aea37fd-7579-4843-addf-a8d5672c2879
Publikováno v:
Tetrahedron Letters. 42:125-128
This letter describes a method for the synthesis of unsymmetrical phosphinic acids by the phosphinylation of a resin-bound aldehyde and subsequent ‘P’ alkylation. This synthetic transformation is very difficult to perform as selectively in soluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e97031f3cea92c5a4c6e2ea89d2fe07
https://doi.org/10.1016/s0040-4039(00)01897-9
https://doi.org/10.1016/s0040-4039(00)01897-9
Autor:
E.Andrew Boyd, Anthony David Baxter, Claude Monteils, Andrew D. Proud, Vincent M. Loh, Philip B Cox
Publikováno v:
Tetrahedron Letters. 41:8177-8181
This letter describes a novel, flexible, solid phase route to pyrimidine-based heterocycles that utilises commercially available 4,6-dichloro-5-nitropyrimidine. This was exemplified by the synthesis of dihydropteridinones.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ee6604c52da98732e80f34a6e5e4d6c
https://doi.org/10.1016/s0040-4039(00)01427-1
https://doi.org/10.1016/s0040-4039(00)01427-1
Publikováno v:
Molecular Diversity. 3:117-120
4-Fluoro-3-nitrobenzoic acid attached to a solid support was shown to react under mild conditions with a wide range of functionalized phenols to yield, after cleavage, the corresponding biaryl ethers in excellent purity. In a similar fashion, biaryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abf6f0a3b5613decb90373be3a3290aa
https://doi.org/10.1023/a:1009654412641
https://doi.org/10.1023/a:1009654412641
Publikováno v:
Tetrahedron Letters. 38:8375-8378
A general method for the construction of tetrahydro-1,4-benzodiazepine-2-ones on solid-support has been developed utilising a cleavage-conjugate addition protocol as the key step in the design. Using this novel methodology the synthesis of a diverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cd24cd7b9fb851b801e8120a63f0b2d
https://doi.org/10.1016/s0040-4039(97)10170-8
https://doi.org/10.1016/s0040-4039(97)10170-8
Publikováno v:
Molecular Diversity. 3:195-198
A novel general protocol for the construction of hydantoins and thiohydantoins on a solid support has been developed. Using this novel methodology, the synthesis of a diverse 96-compound library has been achieved. Resin-bound dipeptides are cyclised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f33e02fd3352b9ecc007220f2dc22a8a
https://doi.org/10.1023/a:1009612923900
https://doi.org/10.1023/a:1009612923900
Autor:
Adrian P. Higson, Gerard K. Scott, Anthony David Baxter, Richard Cosstick, Roger A. Taylor, David J. Earnshaw
Publikováno v:
Tetrahedron. 52:1027-1034
A general procedure for the preparation of S -nucleosidyl S -aryl disulfides from the corresponding thioesters is described. This procedure has been used for the preparation of a ribonucleoside disulphide ( 8d ), a key intermediate for the synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d35a4977b09377f5341a14c068f862f
https://doi.org/10.1016/0040-4020(95)00936-1
https://doi.org/10.1016/0040-4020(95)00936-1
Autor:
Gerard K. Scott, Anthony David Baxter, Joseph S. Vyle, Roger John Taylor, Xiang Li, Richard Cosstick
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :2123-2129
The 5′-O-monomethoxytrityl-3′-S-(aryldisulfanyl)-3′-deoxythymidines 7 and 8 have been prepared by the reaction of 5′-O-monomethoxytrityl-3′-thiothymidine with the appropriate arenesulfenyl chloride. These disulfides undergo a Michaelis–Ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df0bc0c94d62f177706f759fd7c47c13
https://doi.org/10.1039/p19940002123
https://doi.org/10.1039/p19940002123
Autor:
David J. Earnshaw, Gerard K. Scott, Adrian P. Higson, Roger A. Taylor, Anthony David Baxter, Richard Cosstick
Publikováno v:
ChemInform. 27
A general procedure for the preparation of S -nucleosidyl S -aryl disulfides from the corresponding thioesters is described. This procedure has been used for the preparation of a ribonucleoside disulphide ( 8d ), a key intermediate for the synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bca512be094f922760a98bfcbd8085ca
https://doi.org/10.1002/chin.199617225
https://doi.org/10.1002/chin.199617225