Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Anthony D. Maher"'
Autor:
Anthony D. Maher, Simone J. Rochfort
Publikováno v:
Metabolites, Vol 4, Iss 1, Pp 131-141 (2014)
NMR is a robust analytical technique that has been employed to investigate the properties of many substances of agricultural relevance. NMR was first used to investigate the properties of milk in the 1950s and has since been employed in a wide range
Externí odkaz:
https://doaj.org/article/3e17d278bc5442738ef213a7551b77fa
Autor:
George Nicholson, Mattias Rantalainen, Anthony D Maher, Jia V Li, Daniel Malmodin, Kourosh R Ahmadi, Johan H Faber, Ingileif B Hallgrímsdóttir, Amy Barrett, Henrik Toft, Maria Krestyaninova, Juris Viksna, Sudeshna Guha Neogi, Marc‐Emmanuel Dumas, Ugis Sarkans, The MolPAGE Consortium, Bernard W Silverman, Peter Donnelly, Jeremy K Nicholson, Maxine Allen, Krina T Zondervan, John C Lindon, Tim D Spector, Mark I McCarthy, Elaine Holmes, Dorrit Baunsgaard, Chris C Holmes
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-12 (2011)
Abstract 1H Nuclear Magnetic Resonance spectroscopy (1H NMR) is increasingly used to measure metabolite concentrations in sets of biological samples for top‐down systems biology and molecular epidemiology. For such purposes, knowledge of the source
Externí odkaz:
https://doaj.org/article/f335db8f4a53437692b5541fc67ede7b
Publikováno v:
Food Research International. 54:1302-1312
This study has undertaken a metabolomic assessment of Australian blue mussels, (Mytilus galloprovincialis). A comparison to the New Zealand green lipped mussel (Perna canaliculus) was also made. The aqueous metabolomes were investigated by NMR and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ea866f44f66ca564af2503c516f142
https://doi.org/10.1016/j.foodres.2013.03.004
https://doi.org/10.1016/j.foodres.2013.03.004
Autor:
Benjamin G. Cocks, Simone Rochfort, Leah C. Marett, William J. Wales, Anthony D. Maher, Benjamin J. Hayes
Publikováno v:
Journal of Proteome Research. 12:1428-1435
A detailed understanding of the relationships between the distinct metabolic compartments of blood and milk would be of potential benefit to our understanding of the physiology of lactation, and potentially for development of biomarkers for health an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d03436d7c562b478c47aa4e945e49b
https://doi.org/10.1021/pr301056q
https://doi.org/10.1021/pr301056q
Autor:
Bernard W. Balleine, Anthony D. Maher, Teri M. Furlong, Fatima A. Nasrallah, Laura H. Corbit, Caroline Rae, Benjamin D. Rowlands, Jhodie R. Duncan, Carol J. Milligan, Steven Petrou, Andrew J Lawrence
Publikováno v:
Journal of neurochemistry. 139(5)
Toluene is a commonly abused inhalant that is easily accessible to adolescents. Despite the increasing incidence of use, our understanding of its long-term impact remains limited. Here, we used a range of techniques to examine the acute and chronic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ef16edad0cb9b10fcbb8a38d3274f2
https://pubmed.ncbi.nlm.nih.gov/27696399
https://pubmed.ncbi.nlm.nih.gov/27696399
Publikováno v:
Current Metabolomics. 1:2-14
Investigation of the metabolic status of the brain is problematic due to its inaccessibility. NMR-based me- tabolomics offers potential diagnostic capabilities via measurement of brain or related biofluid metabolic profiles. In this review we examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036b131254931a57713c719d38f85747
https://doi.org/10.2174/2213235x130102
https://doi.org/10.2174/2213235x130102
Publikováno v:
Journal of Neurochemistry. 115:58-67
Gamma-hydroxybutyrate is found both naturally in the brain and self-administered as a drug of abuse. It has been reported to act at endogenous γ-hydroxybutyrate (GHB) receptors and GABA(B) receptors [GABA(B)R], and may also be metabolized to GABA. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f96662f364f6e228e7277c2cfe744b6d
https://doi.org/10.1111/j.1471-4159.2010.06901.x
https://doi.org/10.1111/j.1471-4159.2010.06901.x
Autor:
John C. Lindon, Muireann Coen, Elaine Holmes, Jeremy K. Nicholson, Anthony D. Maher, Judith M. Fonville
Publikováno v:
Analytical Chemistry. 82:1811-1821
Spectroscopic profiling of biological samples is an integral part of metabolically driven top-down systems biology and can be used for identifying biomarkers of toxicity and disease. However, optimal biomarker information recovery and resonance assig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae7dca441962ea8f3b300de5bb8d80b
https://doi.org/10.1021/ac902443k
https://doi.org/10.1021/ac902443k
Publikováno v:
Future Medicinal Chemistry. 1:737-747
Diabetes is characterized by hyperglycemia due to dysfunction of insulin secretion or action. The two most common forms are Type 1 diabetes, in which pancreatic β-cells are destroyed, and Type 2 diabetes, in which a combination of disordered insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19eb8a7152bf33db43e59751565053b4
https://doi.org/10.4155/fmc.09.54
https://doi.org/10.4155/fmc.09.54
Autor:
John C. Lindon, Elaine Holmes, Paul Elliott, Elizabeth J. Want, Jeremiah Stamler, Geoffrey E. Hawkes, Leon M. Smith, Jeremy K. Nicholson, Anthony D. Maher
Publikováno v:
Analytical Chemistry. 81:4847-4856
Borate is an antibacterial preservative widely used in clinical and large-scale epidemiological studies involving urine sample analysis. Since it readily forms covalent adducts and reversible complexes with hydroxyl and carboxylate groups, the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53567720bf79d8986d19239aee8911e7
https://doi.org/10.1021/ac9004875
https://doi.org/10.1021/ac9004875