Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anthony D. Kanavage"'
Autor:
Su Wang, Julie M. Skinner, Matthew Miezeiewski, Jon H. Heinrichs, Joseph M. Antonello, Irene Rogers, Melanie Horton, Jean-Luc Bodmer, Jinfu Xie, Lani Indrawati, Julie Zorman, Anthony D. Kanavage, Susan Secore, Yuhua Zhang, Keri Soring
Publikováno v:
Clinical and Vaccine Immunology. 20:517-525
Clostridium difficile produces two major virulence toxins, toxin A (TcdA) and toxin B (TcdB). Antitoxin antibodies, especially neutralizing antibodies, have been shown to be associated with a lower incidence of C. difficile infection (CDI) recurrence
Autor:
David S. Thiriot, Jon H. Heinrichs, Geethanjali Dornadula, Bei Wang, Anthony D. Kanavage, Adam Kristopeit, Jeffrey T. Blue, Richard R. Rustandi, Laura Hong, Su Wang, Feng Wang, Henryk Mach, Susan Secore, Christopher D. Mensch
Publikováno v:
Vaccine. 33(1)
The toxicity of Clostridium difficile large clostridial toxin B (TcdB) can be reduced by many orders of magnitude by a combination of targeted point mutations. However, a TcdB mutant with five point mutations (referred to herein as mTcdB) still has r
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 47(4)
Reconstitution of lyophilized antivenom is usually accomplished by gentle swirling for sometimes as much as 45 min. Gentle resuspension is employed in order to avoid foaming the antivenom, which could have a variety of consequences including unfoldin