Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Anthony D Metcalfe"'
Autor:
Jason K F Wong, Anthony D Metcalfe, Richard Wong, Jim Bush, Chris Platt, Arnaud Garcon, Nick Goldspink, Duncan A McGrouther, Mark W J Ferguson
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112672 (2014)
Repaired tendons may be complicated by progressive fibrosis, causing adhesion formation or tendon softening leading to tendon rupture and subsequent reduced range of motion. There are few therapies available which improve the gliding of damaged tendo
Externí odkaz:
https://doaj.org/article/6fb89e5456814a28854678a7b69b2c8f
Autor:
Thomas E. Robinson, Mathieu Y. Brunet, Iain Chapple, Adrian H. M. Heagerty, Anthony D. Metcalfe, Liam M. Grover
Publikováno v:
Advanced NanoBiomed Research, Vol 3, Iss 9, Pp n/a-n/a (2023)
Fibrotic diseases account for 45% of all deaths in the developed world, and progressive scarring conditions, such as dystrophic epidermolysis bullosa (EB), result in a significant reduction in quality of life. There is thus a need for novel approache
Externí odkaz:
https://doaj.org/article/dfac4e27a1f3466daebe338d236ee8db
Autor:
Richard J. A. Moakes, Jessica J. Senior, Thomas E. Robinson, Miruna Chipara, Aleksandar Atanasov, Amy Naylor, Anthony D. Metcalfe, Alan M. Smith, Liam M. Grover
Publikováno v:
APL Bioengineering, Vol 7, Iss 2, Pp 029901-029901-1 (2023)
Externí odkaz:
https://doaj.org/article/cdae3640089c4f31a95871dfbe3a277c
Autor:
Anu K. Solanki, Hélène Autefage, Antonio R. Rodriguez, Shweta Agarwal, Joaquin Penide, Muzamir Mahat, Thomas Whittaker, Amy Nommeots-Nomm, Elena Littmann, David J. Payne, Anthony D. Metcalfe, Felix Quintero, Juan Pou, Molly M. Stevens, Julian R. Jones
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction and Methods: Chronic wounds are a major healthcare problem, but their healing may be improved by developing biomaterials which can stimulate angiogenesis, e.g. by activating the Hypoxia Inducible Factor (HIF) pathway. Here, novel glass f
Externí odkaz:
https://doaj.org/article/43a1f507d4d04388a5b35696a317e312
Autor:
Alexandra Iordachescu, Erik A. B. Hughes, Stephan Joseph, Eric J. Hill, Liam M. Grover, Anthony D. Metcalfe
Publikováno v:
npj Microgravity, Vol 7, Iss 1, Pp 1-21 (2021)
Abstract Bone is a highly responsive organ, which continuously adapts to the environment it is subjected to in order to withstand metabolic demands. These events are difficult to study in this particular tissue in vivo, due to its rigid, mineralised
Externí odkaz:
https://doaj.org/article/92d0f1bac35a4b89b446ed691ff37888
Autor:
Anu K. Solanki, Ferdinand V. Lali, Hélène Autefage, Shweta Agarwal, Amy Nommeots-Nomm, Anthony D. Metcalfe, Molly M. Stevens, Julian R. Jones
Publikováno v:
Biomaterials Research, Vol 25, Iss 1, Pp 1-16 (2021)
Abstract Background Bioactive glasses are traditionally associated with bonding to bone through a hydroxycarbonate apatite (HCA) surface layer but the release of active ions is more important for bone regeneration. They are now being used to deliver
Externí odkaz:
https://doaj.org/article/77f9147e5c8449be9c6e7133a20e09ce
A suspended layer additive manufacturing approach to the bioprinting of tri-layered skin equivalents
Autor:
Richard J. A. Moakes, Jessica J. Senior, Thomas E. Robinson, Miruna Chipara, Aleksandar Atansov, Amy Naylor, Anthony D. Metcalfe, Alan M. Smith, Liam M. Grover
Publikováno v:
APL Bioengineering, Vol 5, Iss 4, Pp 046103-046103-11 (2021)
Skin exhibits a complex structure consisting of three predominant layers (epidermis, dermis, and hypodermis). Extensive trauma may result in the loss of these structures and poor repair, in the longer term, forming scarred tissue and associated reduc
Externí odkaz:
https://doaj.org/article/e54a56e99b5148349b07769d429ea532
Autor:
Diana R. Alves, Simon P. Booth, Paola Scavone, Pascale Schellenberger, Jonathan Salvage, Cinzia Dedi, Naing-Tun Thet, A. Toby A. Jenkins, Ryan Waters, Keng W. Ng, Andrew D. J. Overall, Anthony D. Metcalfe, Jonathan Nzakizwanayo, Brian V. Jones
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Biofilm formation in wounds is considered a major barrier to successful treatment, and has been associated with the transition of wounds to a chronic non-healing state. Here, we present a novel laboratory model of wound biofilm formation using ex-viv
Externí odkaz:
https://doaj.org/article/1b2e1f23d5744734befce429e5f8a637
Publikováno v:
Journal of Wound Care. 30:300-303
Objective: Fibroblasts have been shown to play an increasingly important role within diabetic wounds. While several in vitro models of diabetic wound fibroblasts have been reported, none replicate the natural progression of the disease over time, rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b897c531e18933b56360cbb1a88bfb0
https://doi.org/10.12968/jowc.2021.30.4.300
https://doi.org/10.12968/jowc.2021.30.4.300
Publikováno v:
Archives of Dermatological Research
In this study, we characterised the effect that seeding keratinocytes on the papillary and reticular dermis had on the extracellular matrix and tissue integrity ex vivo. Human skin explants from consented patients (n = 6) undergoing routine surgery w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db324fc628d9cdab5ceb2893435892d6
https://doi.org/10.1007/s00403-019-01941-w
https://doi.org/10.1007/s00403-019-01941-w