Výsledky vyhledávání - "Anthony Collmann"

The cellular and biochemical rules of lipid antigen presentation

Autor: Anthony Collmann, Lucia Mori, Gennaro De Libero

Publikováno v: European journal of immunology
European Journal of Immunology; Vol 39
European Journal of Immunology

The recognition of both protein and lipid antigens follows similar strategies that rely on different molecular mechanisms. APC present lipid antigens exploiting the same mechanisms implicated in lipid translocation, lipoprotein assembly and lipid deg

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The assembly of CD1e is controlled by an N-terminal propeptide which is processed in endosomal compartments

Autor: Blandine Maître, Catherine Angénieux, Virginie Wurtz, Emilie Layre, Martine Gilleron, Anthony Collmann, Sabrina Mariotti, Lucia Mori, Dominique Fricker, Jean-Pierre Cazenave, Alain van Dorsselaer, Christian Gachet, Gennaro de Libero, Germain Puzo, Daniel Hanau, Henri de La Salle

Publikováno v: Biochemical Journal; Vol 419
Biochemical Journal
Biochemical Journal, Portland Press, 2009, 419 (3), pp.661-668. ⟨10.1042/BJ20082204⟩
The Biochemical journal

CD1e displays unique features in comparison with other CD1 proteins. CD1e accumulates in Golgi compartments of immature dendritic cells and is transported directly to lysosomes, where it is cleaved into a soluble form. In these latter compartments, C

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Mycolic Acids Constitute a Scaffold for Mycobacterial Lipid Antigens Stimulating CD1-Restricted T Cells

Autor: Max Bastian, Sabrina Mariotti, Steffen Stenger, Lucia Mori, Martine Gilleron, Jacques Prandi, Jerzy Czaplicki, Germain Puzo, Gennaro De Libero, Anthony Collmann, Emilie Layre

Publikováno v: Chemistry & Biology; Vol 16
Chemistry & biology
Chemistry & biology, 2009, 16 (1), pp.82-92. ⟨10.1016/j.chembiol.2008.11.008⟩
Chemistry & Biology

SummaryCD1-restricted lipid-specific T lymphocytes are primed during infection with Mycobacterium tuberculosis, the causative agent of tuberculosis. Here we describe the antigenicity of glycerol monomycolate (GroMM), which stimulates CD1b-restricted

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Cutting Edge: A Naturally Occurring Mutation in CD1e Impairs Lipid Antigen Presentation

Autor: Sylvie Tourne, Blandine Maitre, Anthony Collmann, Emilie Layre, Sabrina Mariotti, François Signorino-Gelo, Caroline Loch, Jean Salamero, Martine Gilleron, Catherine Angénieux, Jean-Pierre Cazenave, Lucia Mori, Daniel Hanau, Germain Puzo, Gennaro De Libero, Henri de la Salle

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 180 (6), pp.3642-3646. ⟨10.4049/jimmunol.180.6.3642⟩
Journal of Immunology, 2008, 180 (6), pp.3642-6
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 180 (6), pp.3642-6
Scopus-Elsevier
ResearcherID

The human CD1a–d proteins are plasma membrane molecules involved in the presentation of lipid Ags to T cells. In contrast, CD1e is an intracellular protein present in a soluble form in late endosomes or lysosomes and is essential for the processing

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https://doi.org/10.4049/jimmunol.180.6.3642

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Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids

Autor: Gennaro De Libero, Martine Gilleron, Anthony Collmann, Thérèse Brando, Albert J. R. Heck, Emilie Huc, Cees Versluis, Lionel Mourey, Luis F. Garcia-Alles, Steven A. Porcelli, Lucia Mori, Buko Lindner, Laurent Maveyraud, Julie Guiard, Germain Puzo, Sylviane Julien, Sebastiano Sansano, Jin S. Im, Jacques Prandi

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2011, 108 (43), pp.17755-17760. ⟨10.1073/pnas.1110118108⟩
Proceedings of the National Academy of Sciences; Vol 108
Proceedings of the National Academy of Sciences

International audience; The mechanisms permitting nonpolymorphic CD1 molecules to present lipid antigens that differ considerably in polar head and aliphatic tails remain elusive. It is also unclear why hydrophobic motifs in the aliphatic tails of so

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cba2261face67ee3bc0c74043b6d06
https://pubmed.ncbi.nlm.nih.gov/22006319

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Fatty Acyl Structures of Mycobacterium tuberculosis Sulfoglycolipid Govern T Cell Response

Autor: Gennaro De Libero, Jacques Prandi, Thérèse Brando, Luis F. Garcia-Alles, Anthony Collmann, Martine Gilleron, Lionel Mourey, Julie Guiard, Germain Puzo, Lucia Mori

CD1b-restricted T lymphocytes recognize a large diversity of mycobacterial lipids, which differ in their hydrophilic heads and the structure of their acyl appendages. Both moieties participate in the antigenicity of lipid Ags, but the structural cons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a580abf189ff7d6096c6a1fd2166e9
https://hal.archives-ouvertes.fr/hal-03003394

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Synthesis of Diacylated Trehalose Sulfates: Candidates for a Tuberculosis Vaccine

Autor: Gennaro De Libero, Jacques Prandi, Julie Guiard, Germain Puzo, Anthony Collmann, Lucia Mori, Martine Gilleron

Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2008, 47 (50), pp.9734-9738. ⟨10.1002/anie.200803835⟩
Angewandte Chemie (International ed. in English)

International audience

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https://hal.archives-ouvertes.fr/hal-03177927

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Differential alteration of lipid antigen presentation to NKT cells due to imbalances in lipid metabolism

Autor: Anthony Collmann, Luigi Panza, Mario Michieletti, Federica Facciotti, Lucia Mori, Jens Schümann, Federica Compostella, Gennaro De Libero

Publikováno v: ResearcherID

Deficiencies in enzymes of the lysosomal glycosphingolipid degradation pathway or in lysosomal lipid transfer proteins cause an imbalance in lipid metabolism and induce accumulation of certain lipids. A possible impact of such an imbalance on the pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c232885946ca5a7ce83fb4e24ffdebd3
http://hdl.handle.net/10281/335287

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