Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anthony C. Segreti"'
Autor:
Noel R. Mohberg, Robert L. Davis, Karl E. Peace, Anthony C. Segreti, Hoi M. Leung, Gary G. Koch
Publikováno v:
Journal of Biopharmaceutical Statistics. 11:347-372
The practice of statistics in the pharmaceutical industry has changed markedly over the last 25 years. This paper examines the evolution of clinical trial statistics in relationship to advances in statistical methodology and computational power as we
Autor:
Charles E. Geyer, M. Walker, S. Stein, Xiaolei Zhou, Mayur M. Amonkar, Anthony C. Segreti, David Cella, David Cameron
Publikováno v:
Breast cancer research and treatment. 117(3)
The randomized phase III trial EGF100151 demonstrated that the combination of lapatinib plus capecitabine (L + C) significantly improved time to progression (TTP) compared with capecitabine alone (C) in heavily pretreated patients with HER2+ (ErbB2+)
Autor:
Anthony C. Segreti, David Cella, David Cameron, Charles E. Geyer, Xiaolei Zhou, M. Walker, Mayur M. Amonkar, S. Stein
Publikováno v:
European Journal of Cancer Supplements. 6:216-217
Autor:
Anthony C. Segreti, David Cella, Charles E. Geyer, David Cameron, Xiaolei Zhou, Mayur M. Amonkar, S. Stein, M. Walker
Publikováno v:
Journal of Clinical Oncology. 26:9532-9532
9532 Background: In a phase III randomized open-label multicenter trial, L+C improved time to progression and progression free survival vs C alone in women with ErbB2+ MBC who had received prior th...
Autor:
Anthony C. Segreti, David Cella, M. Arbushites, Y. Wu, M. Walker, Mayur M. Amonkar, M. Koehler, A. DiLeo
Publikováno v:
European Journal of Cancer Supplements. 6:171
Autor:
Oscar L. Laskin, Ronald E. Keeney, L. E. Kirk, Henry H. Balfour, John A. Zaia, Richard F. Ambinder, Dorothee M. Aeppli, Anthony C. Segreti, James C. Wade, Joel D. Meyers, Bonnie Bean
Publikováno v:
New England Journal of Medicine. 308:1448-1453
We conducted a placebo-controlled, double-blind study of acyclovir therapy for acute herpes zoster in immunocompromised patients. Of the 94 patients enrolled in the study, 52 had localized skin lesions at entry, and 42 had disseminated cutaneous zost
Publikováno v:
Journal of the American Academy of Dermatology. 13:590-596
Topical acyclovir favorably influences the healing of localized herpes zoster in immunocompromised patients. This therapy, or placebo, was applied to forty-three patients in a random access, double-blind trial, four times daily for 10 days, beginning
Autor:
Bert Spilker, Anthony C. Segreti
Publikováno v:
Epilepsia. 25:443-449
Summary: A phenomenon known as regression of seizure frequency toward the median was observed in a previous clinical study performed in patients with partial seizures. Regression of seizure frequency is a situation in which patients with a frequency
Autor:
Anthony C. Segreti, Gary N. Foulks, Jonathan H. Lass, Sharon Chapman, Thomas J. Liesegang, Daniel B. Jones, John E. Sutphin, L. Michael Cobo, Kirk R. Wilhelmus
Publikováno v:
Ophthalmology. 92:1574-1583
A prospective, randomized, double-masked, placebo-controlled clinical trial was conducted to study the effects of oral acyclovir on 55 patients with acute herpes zoster ophthalmicus. Treatment with oral acyclovir resulted in more prompt resolution of
Autor:
Anthony C. Segreti, Daniel B. Jones, Jonathan H. Lass, Gary N. Foulks, D. H. King, John E. Sutphin, Kirk R. Wilhelmus, T. Liesegang, L. M. Cobo, Sharon Chapman
Publikováno v:
Ophthalmology. 93(6)
Seventy-one nonimmunocompromised patients with herpes zoster ophthalmicus, presenting within seven days of onset of characteristic skin eruption, were enrolled in a prospective, longitudinal, randomized, double-masked, placebo-controlled trial with o