Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anthony C. Saulewicz"'
Publikováno v:
Journal of Cellular Physiology. 158:270-276
We have investigated the capacity of a murine cell line with a temperature-sensitive (ts) mutation in the DNA polymerase alpha (Pola) locus and a series of ts non-Pola mutant cell lines from separate complementation groups to stimulate DNA synthesis,
Autor:
Yoshihiro Takihara, Xiaoqin Chen, Thomas H. Norwood, Motoaki Ohtsubo, Matthew D. Gray, Maria Tresini, Anthony C. Saulewicz, Deborah E. Banker, Ping Luo, Aloysius L. Klingelhutz, Vincent J. Cristofalo
Publikováno v:
Experimental cell research. 294(2)
Human diploid fibroblasts (HDF) rarely, if ever, undergo spontaneous transformation to an immortalized cell type. Here we report the immortalization of an HDF cell line following transduction with cyclin A2 or cdk1 human genes via retroviral vectors.
Publikováno v:
Experimental gerontology. 27(4)
Publikováno v:
Experimental cell research. 192(2)
We have previously reported that the DNA polymerase alpha activity/unit cellular protein is decreased in late-passage (senescent) human diploid fibroblast-like (HDFL) cultures due to the cellular enlargement associated with in vitro aging. In the stu
Publikováno v:
Journal of cellular physiology. 124(2)
DNA polymerase alpha activity was determined following serum stimulation of early and late passages of human diploid fibroblast-like (HDFL) cultures derived from apparently normal donors (two strains) and from a patient with Werner's syndrome (one st
Autor:
George M. Martin, Glenna C. Burmer, Anthony C. Saulewicz, William R. Pendergrass, Peter S. Rabinovitch, Thomas H. Norwood
Publikováno v:
Journal of cellular physiology. 113(1)
The specific activity of DNA polymerase (90% alpha) was determined in nine "neoplastoid" cell lines (Martin and Sprague, 1973) and in three different strains of HDF (human diploid fibroblast-like cells), all examined in logarithmic phases of growth.