Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Anthony C. Santucci"'
Autor:
Anthony C. Santucci, Donald Rabidou
Publikováno v:
Addiction Biology. 16:30-42
The present study was conducted to determine whether cognitive impairments in adult rats treated with cocaine during adolescence demonstrated in previous investigations extend to tests of object discrimination learning. Accordingly, 30-day-old male L
Autor:
Albania Rosario, Anthony C. Santucci
Publikováno v:
Brain Research Bulletin. 81:441-444
The present study was conducted to determine whether increases in anxiety-like behavior in adolescent rats repeatedly treated with cocaine would be observed following a withdrawal period of an intermediate length (i.e., more than 1 day but less than
Autor:
Anthony C. Santucci, Julia Cardiello
Publikováno v:
Behavioral Neuroscience. 118:248-252
The effect of various doses of the serotonin-1A agonist 8-OH-DPAT at training on 72-hr retention of passive avoidance was investigated in rats. Results indicated impaired retention, as measured by latency to avoid shock. However, when total time spen
Autor:
Jun Yao, Ozlem Bozdagi, Nikhat F. Zaidi, Anthony C. Santucci, Sam Gandy, Manuel Gomez-Ramirez, Christina Lilliehook, Vahram Haroutunian, Joseph D. Buxbaum, George W. Huntley, Wilma Wasco
Publikováno v:
Scopus-Elsevier
Calsenilin has been identified as a presenilin-binding protein, a transcription factor regulating dynorphin expression, and a β-subunit of Kv4 channels and could, thus, be a multifunctional protein. To study these functions of calsenilinin vivoand t
Autor:
Christina Shaw, Anthony C. Santucci
Publikováno v:
Neurobiology of Learning and Memory. 79:136-141
The present study determined whether peripheral injections of the 5HT(1A) agonist (8-OH-DPAT), scopolamine infusions into the frontal cortex, or a combination of both drug treatments would produce impairments in rats trained on passive avoidance. Usi
Autor:
Sarah Perez, Anthony C. Santucci
Publikováno v:
Behavioural Brain Research. 136:433-438
The learning and memory enhancing effects of thyrotropin releasing hormone (TRH) was examined in an animal model of Alzheimer's disease. Adult rats were prepared with either sham surgeries or cholinergic lesions of the nucleus basalis of Meynert (nbM
Publikováno v:
Psychobiology. 23:139-143
The effects of serotonergic lesions of the nucleus basalis of Meynert (nbM) or regions within the frontal cortex (FCTX) induced with 5,7-dihydroxytryptamine were examined to determine whether such damage would block the amnesia-producing effect of pr
Publikováno v:
Neurobiology of Learning and Memory. 63:286-290
The present study investigated the mnemonic consequences of muscarinic blockade in rats pretreated with the serotonergic depleter p-chloroamphetamine (PCA). Subjects were initially injected with either PCA (2.5 mg/kg) or saline (SAL) approximately 1
Autor:
Anthony C. Santucci
Publikováno v:
Behavior Research Methods, Instruments, & Computers. 27:60-64
A relatively inexpensive and reliable computer-aided method for assessing Morris water maze performance is described. The procedure uses SigmaScan digitizing software (Jandel Scientific, San Rafael, CA) to collect distance swum data, while escape lat
Publikováno v:
Brain Research. 609:327-332
To investigate the efficacy of nerve growth factor (NGF) in promoting recovery from cholinergic damage, young (3–4 month old) and aged (22–23 month old) Fischer 344 rats received NMDA-induced unilateral lesions of the nucleus basalis of Meynert a