Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Anthony C. Arvanites"'
Autor:
Cameron Sadegh, Wataru Ebina, Anthony C Arvanites, Lance S Davidow, Lee L Rubin, Jeffrey D Macklis
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0254113 (2021)
During late embryonic development of the cerebral cortex, the major class of cortical output neurons termed subcerebral projection neurons (SCPN; including the predominant population of corticospinal neurons, CSN) and the class of interhemispheric ca
Externí odkaz:
https://doaj.org/article/8b8b338a1dfe4519a368f43681540992
Autor:
Barak Blum, Adam N Roose, Ornella Barrandon, René Maehr, Anthony C Arvanites, Lance S Davidow, Jeffrey C Davis, Quinn P Peterson, Lee L Rubin, Douglas A Melton
Publikováno v:
eLife, Vol 3 (2014)
Dysfunction or death of pancreatic β cells underlies both types of diabetes. This functional decline begins with β cell stress and de-differentiation. Current drugs for type 2 diabetes (T2D) lower blood glucose levels but they do not directly allev
Externí odkaz:
https://doaj.org/article/3ad5b45b82e84774b6e71116e7e9164d
Autor:
Lee L. Rubin, Anthony C. Arvanites, Lance S. Davidow, Cameron Sadegh, Jeffrey D. Macklis, Wataru Ebina
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0254113 (2021)
PLoS ONE
PLoS ONE
During late embryonic development of the cerebral cortex, the major class of cortical output neurons termed subcerebral projection neurons (SCPN; including the predominant population of corticospinal neurons, CSN) and the class of interhemispheric ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc4498fae1b76f9ff4bc4b7d47889c6
https://doaj.org/article/8b8b338a1dfe4519a368f43681540992
https://doaj.org/article/8b8b338a1dfe4519a368f43681540992
Autor:
Cameron Sadegh, Wataru Ebina, Jeffrey D. Macklis, Anthony C. Arvanites, Lee L. Rubin, Lance S. Davidow
During late embryonic development of the cerebral cortex, the major class of cortical output neurons termed subcerebral projection neurons (SCPN; including the predominant population of corticospinal neurons, CSN) and the class of interhemispheric ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9548a5d31781b98cd8ea356eedfc0065
https://doi.org/10.1101/2020.08.13.242230
https://doi.org/10.1101/2020.08.13.242230
Autor:
Lee L. Rubin, Clifford J. Woolf, Bjoern Schwer, Frederick W. Alt, Devlin Frost, Riki Kawaguchi, Jelena Ivanis, Priscilla Riva, Yung-Chih Cheng, Lance S. Davidow, Michael Costigan, Anthony C. Arvanites, Alyssa Grantham, Andrew Snavely, Eric A. Huebner, Rie Maeda, Ivan Tochitsky, Crystal Herman, Vatsal Oza, Xuefei Zhang, Giovanni Coppola, Bhagat Singh, Lee Barrett, Q. Wang, Kathleen L. Pfaff, Amelia N. Chang, Miyuki Sakuma
Publikováno v:
Cell Reports. 36:109666
Although axonal damage induces rapid changes in gene expression in primary sensory neurons, it remains unclear how this process is initiated. The transcription factor ATF3, one of the earliest genes responding to nerve injury, regulates expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cd513058920d9d4bb92c0fac0189bf
https://doi.org/10.1016/j.celrep.2021.109666
https://doi.org/10.1016/j.celrep.2021.109666
Autor:
Jennifer Hollister-Lock, Jennifer Hyoje Ryu, Nigam H. Shah, Justin P. Annes, Gordon C. Weir, Neali A Armstrong, Zhenshan Zhao, Yen Low, Anthony C. Arvanites, Sara A. Sun
Publikováno v:
Molecular Endocrinology. 28:1682-1697
Loss of β-cell mass is a cardinal feature of diabetes. Consequently, developing medications to promote β-cell regeneration is a priority. cAMP is an intracellular second messenger that modulates β-cell replication. We investigated whether medicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236f566cf7276d9b1cafe6cfb0ad9948
https://doi.org/10.1210/me.2014-1120
https://doi.org/10.1210/me.2014-1120
Autor:
Hien D. Ngo, Kathryn A. Rosowski, Clifford J. Woolf, Shailesh Kumar Gupta, Lee L. Rubin, Anthony C. Arvanites, Kevin J. Kim, Pamela A. Schein, Courtney A. Ackeifi, Brian J. Wainger, Lance S. Davidow, Antonio Cerqueira, Yin M. Yang, Berit E. Powers
Publikováno v:
Cell Stem Cell. 12(6):713-726
SummaryAmyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease, characterized by motor neuron (MN) death, for which there are no truly effective treatments. Here, we describe a new small molecule survival screen carried
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124f120894f7c48eb3c5764254bbe46e
Autor:
Robert J. Ferrante, Wei Zhang, Radhia Benmohamed, Richard B. Silverman, Richard I. Morimoto, Anthony C. Arvanites, Donald R. Kirsch
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:1029-1045
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons. Currently, there is only one FDA-approved treatment for ALS (riluzole), and that drug only extends life, on average, by 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e87436672ce017e8372adf96b69374c
https://doi.org/10.1016/j.bmc.2011.11.039
https://doi.org/10.1016/j.bmc.2011.11.039
Autor:
Guoyao Xia, Robert J. Ferrante, Anthony C. Arvanites, Radhia Benmohamed, Richard I. Morimoto, Jinho Kim, Richard B. Silverman, Donald R. Kirsch
Publikováno v:
Journal of Medicinal Chemistry. 54:2409-2421
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons, leading to muscle weakness, paralysis, and death, most often from respiratory failure. The only FDA-approved drug for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd9f8100b9c88d0aed77a0e290ef932a
https://doi.org/10.1021/jm101549k
https://doi.org/10.1021/jm101549k
Autor:
Richard B. Silverman, Robert J. Ferrante, Radhia Benmohamed, Tian Chen, Richard I. Morimoto, Hantamalala Ralay Ranaivo, Anthony C. Arvanites, D. Martin Watterson, Donald R. Kirsch
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:613-622
Amyotrophic lateral sclerosis (ALS) is an orphan neurodegenerative disease currently without a cure. Mutations in copper/zinc superoxide dismutase 1 (SOD1) have been implicated in the pathophysiology of this disease. Using a high-throughput screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0201456995f64b4dff375b9ff5777a5
https://doi.org/10.1016/j.bmc.2010.10.052
https://doi.org/10.1016/j.bmc.2010.10.052