Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anthony Bais"'
Autor:
Anthony Bais, Qiangzhong Ma, Stephen I. Cohen, A. Samer Al-Homsi, Erica M. Gomes, Howard Cabral, Mehrdad Abedi, Richard P. Junghans, Ritesh Rathore, Robin Davies, Agnes Lo
Publikováno v:
The Prostate. 76:1257-1270
BACKGROUND Chimeric antigen receptor (CAR)-modified “designer” T cells (dTc, CAR-T) against PSMA selectively target antigen-expressing cells in vitro and eliminate tumors in vivo. Interleukin 2 (IL2), widely used in adoptive therapies, was proven
Autor:
Anthony Bais, Sadhak Sengupta, Jinyuan Zhou, Richard P. Junghans, Henry Brem, Qiangzhong Ma, Saryn Doucette, Betty Tyler, Bob S. Carter, Seogkyoung Kong, Ayguen Sahin, Prakash Sampath
Publikováno v:
Clinical Cancer Research. 18:5949-5960
Purpose: Glioblastoma multiforme (GBM) remains highly incurable, with frequent recurrences after standard therapies of maximal surgical resection, radiation, and chemotherapy. To address the need for new treatments, we have undertaken a chimeric anti
Publikováno v:
The FASEB Journal. 22
Publikováno v:
Journal of virological methods. 148(1-2)
Vector producer cells are derived from helper cell lines expressing viral proteins that have been transduced to express a transgene-carrying retroviral genome. Vector producing cells express two relevant forms of RNA in their cytoplasm: vector RNA (v
Autor:
Steven M Sepe, Eung Jun Im, Qiangzhong Ma, Wen Yang, Richard P. Junghans, Xiuyang Guo, Anthony Bais
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Transduction and expression procedures in gene therapy protocols may optimally transfer more than a single gene to correct a defect and/or transmit new functions to recipient cells or organisms. This may be accomplished by transduction with two (or m
Publikováno v:
The Journal of Immunology. 190:177.14-177.14
Ample co-stimulatory interactions between antigen-presenting cells and T cells are essential for an effective immune response. Similarly, co-stimulation related immuno-experiences have also been considered critical for the successful tumor eradicatio
Autor:
Steven I. Cohen, Erica M. Gomes, Ritesh Rathore, Ryan Harvey, Qiangzhong Ma, Anthony Bais, Richard P. Junghans, Robin Davies
Publikováno v:
Cancer Research. 72:C13-C13
Introduction: We created chimeric antigen receptors (CAR) specific for prostate specific membrane antigen (PSMA). When expressed in patient T cells, these “designer T cells” (dTc) specifically kill prostate cancer cells in vitro and in vivo in an
Autor:
Nithianandan Selliah, Gail Skowron, Anthony Bais, Erica Gomes, Li Lu, Wen Yang, Richard Junghans
Publikováno v:
The Journal of Immunology. 184:52.19-52.19
Immunotherapies that have the potential to eradicate reservoirs of HIV infected cells may be useful to suppress or cure HIV/AIDS. T cells expressing chimeric immune receptors (CIR) through gene modification (designer T cells) can be redirected to kil
Autor:
Anthony Bais, Abdul Saied, Anthony Razzak, N. Joseph Espat, Ponnandai Somasundar, Justin Hering
Publikováno v:
Gastroenterology. 136:A-936