Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Anthony B, Mak"'
This book describes how one can use The Scientific Method to solve everyday problems including medical ailments, health issues, money management, traveling, shopping, cooking, household chores, etc. It illustrates how to exploit the information colle
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities
Autor:
Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O'Brien, Brenda Andrews, Charles Boone, Jason Moffat
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-17 (2013)
Abstract Improved efforts are necessary to define the functional product of cancer mutations currently being revealed through large‐scale sequencing efforts. Using genome‐scale pooled shRNA screening technology, we mapped negative genetic interac
Externí odkaz:
https://doaj.org/article/8a63360e433a4b2bb265d3be099523e4
Autor:
Anthony B. Mak, Allison M.L. Nixon, Saranya Kittanakom, Jocelyn M. Stewart, Ginny I. Chen, Jasna Curak, Anne-Claude Gingras, Ralph Mazitschek, Benjamin G. Neel, Igor Stagljar, Jason Moffat
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 951-963 (2012)
The pentaspan membrane glycoprotein CD133 marks lineage-specific cancer progenitor cells and is associated with poor prognosis in a number of tumor types. Despite its utility as a cancer progenitor cell marker, CD133 protein regulation and molecular
Externí odkaz:
https://doaj.org/article/7c367e4d72024b2cb906fd603be9e02d
This book describes how one can use The Scientific Method to solve everyday problems including medical ailments, health issues, money management, traveling, shopping, cooking, household chores, etc. It illustrates how to exploit the information colle
Autor:
Jason Moffat, Andrea Uetrecht, Mariana Pehar, Allison M.L. Nixon, Luigi Puglielli, Anthony B. Mak, Rashida Williams
Publikováno v:
Journal of Molecular Biology. 426:2175-2182
The CD133 cell-surface protein expresses the AC133 epitope that is associated with cancer progenitor cells and cancer resistance to traditional anticancer therapies. We report that the endoplasmic reticulum Golgi intermediate compartment residing ace