Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anthony Azzara"'
Autor:
Susheel J. Nara, Srinivas Jogi, Srinivas Cheruku, Sarkunam Kandhasamy, Firoz Jaipuri, Pavan Kalyan Kathi, Subba Reddy, Sanket Sarodaya, Erica M. Cook, Tao Wang, Doree Sitkoff, Karen A. Rossi, Max Ruzanov, Susan E. Kiefer, Javed A. Khan, Mian Gao, Satyanarayana Reddy, Sankara Sivaprasad LVJ, Ramola Sane, Kathy Mosure, Xiaoliang Zhuo, Gary G. Cao, Milinda Ziegler, Anthony Azzara, John Krupinski, Matthew G. Soars, Bruce A. Ellsworth, Dean A. Wacker
Publikováno v:
Journal of medicinal chemistry. 65(13)
While several farnesoid X receptor (FXR) agonists under clinical investigation for the treatment of nonalcoholic steatohepatitis (NASH) have shown beneficial effects, adverse effects such as pruritus and elevation of plasma lipids have limited their
Publikováno v:
Journal of Hepatology. 73:S519-S520
Autor:
Yves Deshaies, Gerald I. Shulman, Mark F. Mehler, Mathieu Laplante, Ja Young Kim, Philipp E. Scherer, Guangyu Li, Jorge L. Durand, Hua Li, Esther Van De Wall, David Y. Hui, Anthony Azzara, Maria E. Trujillo, Todd Schraw, Linda A. Jelicks, Gary J. Schwartz, Susanna M. Hofmann
Publikováno v:
Journal of Clinical Investigation. 117:2621-2637
Excess caloric intake can lead to insulin resistance. The underlying reasons are complex but likely related to ectopic lipid deposition in nonadipose tissue. We hypothesized that the inability to appropriately expand subcutaneous adipose tissue may b