Zobrazeno 1 - 10
of 1 602
pro vyhledávání: '"Anthony Atala"'
Autor:
Bradford M. Kuhlman, Jonathan H. Diaz, Trang Simon, Kimberly D. Reeves, Stephen J. Walker, Anthony Atala, Graça Almeida-Porada, Christopher D. Porada
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Natural killer (NK) cells are an important first-line of defense against malignant cells. Because of the potential for increased cancer risk from astronaut exposure to space radiation, we determined whether microgravity present during spacef
Externí odkaz:
https://doaj.org/article/45be455f383044bebbf1249825b076d6
Autor:
Zuyan Lu, XiangWan Miao, Chenyu Zhang, Binbin Sun, Aleksander Skardal, Anthony Atala, Songtao Ai, JiaNing Gong, Yongqiang Hao, Jie Zhao, Kerong Dai
Publikováno v:
Bioactive Materials, Vol 34, Iss , Pp 1-16 (2024)
Marrow niches in osteosarcoma (OS) are a specialized microenvironment that is essential for the maintenance and regulation of OS cells. However, existing animal xenograft models are plagued by variability, complexity, and high cost. Herein, we used a
Externí odkaz:
https://doaj.org/article/9d9aef118d7e4785856915061faa6455
Autor:
Mostafa Rezapour, Stephen J. Walker, David A. Ornelles, Muhammad Khalid Khan Niazi, Patrick M. McNutt, Anthony Atala, Metin Nafi Gurcan
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
In this study, we delved into the comparative analysis of gene expression data across RNA-Seq and NanoString platforms. While RNA-Seq covered 19,671 genes and NanoString targeted 773 genes associated with immune responses to viruses, our primary focu
Externí odkaz:
https://doaj.org/article/45e6291e6e7c4df7995fbfbb6fe5d8ed
Autor:
Caroline E. Kuczynski, Christopher D. Porada, Anthony Atala, Samuel S. Cho, Graça Almeida-Porada
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Sickle cell disease (SCD) affects millions worldwide, yet there are few therapeutic options. To develop effective treatments, preclinical models that recapitulate human physiology and SCD pathophysiology are needed. SCD arises from a single
Externí odkaz:
https://doaj.org/article/5b1dcff094484a8ea1c2d3aca17ce1a5
Autor:
Adam B. Cohen, Banafsheh Nikmehr, Omar A. Abdelaal, Megan Escott, Stephen J. Walker, Anthony Atala, Hooman Sadri-Ardekani
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1774 (2024)
Spermatogenesis produces male gametes from spermatogonial stem cells (SSC), beginning at puberty. Modern-day laboratory techniques allow for the long-term culture of SSC and in vitro spermatogenesis. The specific biochemical processes that occur duri
Externí odkaz:
https://doaj.org/article/355ab1932dd34d8abcb6c7ba16355e64
Autor:
Mostafa Rezapour, Stephen J. Walker, David A. Ornelles, Patrick M. McNutt, Anthony Atala, Metin Nafi Gurcan
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionOur study undertakes a detailed exploration of gene expression dynamics within human lung organ tissue equivalents (OTEs) in response to Influenza A virus (IAV), Human metapneumovirus (MPV), and Parainfluenza virus type 3 (PIV3) infection
Externí odkaz:
https://doaj.org/article/3aa893f9eca64910900f5de919545a0d
Autor:
Wenjie Zheng, Saiyan Bian, Shi Qiu, Colin E. Bishop, Meimei Wan, Nuo Xu, Xieyin Sun, Russel Clive Sequeira, Anthony Atala, Zhifeng Gu, Weixin Zhao
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-20 (2023)
Abstract Background Extracellular vesicles derived from mesenchymal stem/stromal cells (MSCs) have shown therapeutic effects on liver fibrosis. This study aimed to evaluate the effects of extracellular vesicles from placenta-derived MSCs (Pd-MSCs-EVs
Externí odkaz:
https://doaj.org/article/2d35a46d0fd84fe7b2cea6cf73495fac
Autor:
Guillermo Galdon, Nima Pourhabibi Zarandi, Nicholas A. Deebel, Sue Zhang, Olivia Cornett, Dmitry Lyalin, Mark J. Pettenati, YanHe Lue, Christina Wang, Ronald Swerdloff, Thomas D. Shupe, Colin Bishop, Kimberly Stogner, Stanley J. Kogan, Stuart Howards, Anthony Atala, Hooman Sadri-Ardekani
Publikováno v:
Bioengineering, Vol 11, Iss 7, p 677 (2024)
Increasing survival rates of children following cancer treatment have resulted in a significant population of adult survivors with the common side effect of infertility. Additionally, the availability of genetic testing has identified Klinefelter syn
Externí odkaz:
https://doaj.org/article/0d499f5a34b345c688140e6641678963
Autor:
Martin Rodriguez, Brady Trevisan, Ritu M. Ramamurthy, Sunil K. George, Jonathan Diaz, Jordan Alexander, Diane Meares, Denise J. Schwahn, David R. Quilici, Jorge Figueroa, Michael Gautreaux, Andrew Farland, Anthony Atala, Christopher B. Doering, H. Trent Spencer, Christopher D. Porada, Graça Almeida-Porada
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Hemophilia A is the most common X-linked bleeding disorder affecting more than half-a-million individuals worldwide. Persons with severe hemophilia A have coagulation FVIII levels 3 years post-treatment. Cells engraft in major organs, and no
Externí odkaz:
https://doaj.org/article/85e8ab404d0141858837af84107b16bc
Autor:
Timothy Leach, Uma Gandhi, Kimberly D. Reeves, Kristina Stumpf, Kenichi Okuda, Frank C. Marini, Stephen J. Walker, Richard Boucher, Jeannie Chan, Laura A. Cox, Anthony Atala, Sean V. Murphy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The human airways are complex structures with important interactions between cells, extracellular matrix (ECM) proteins and the biomechanical microenvironment. A robust, well-differentiated in vitro culture system that accurately models thes
Externí odkaz:
https://doaj.org/article/f6aec4b9509d461d8e54e25cfb50ccb8