Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Anthony Anisowicz"'
Autor:
Anthony Anisowicz, Catherine McCauley, Valerie E. Coleburn, Art Morales, Frederick J. Bex, Paul J. Yaworsky, Bheem M. Bhat, James R. Graham, Eric Fortier, Wei Liu, Kristina Allen, Ramesh A. Bhat, Michael Cain, Ho-Sun Lam
Publikováno v:
Gene. 391:103-112
A single point mutation (G to T) in the low-density lipoprotein receptor related protein 5 (LRP5) gene results in a glycine to valine amino acid change (G171V) and is responsible for an autosomal dominant high bone mass trait (HBM) in two independent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1c5e29df928065d39b01251db93d1f
https://doi.org/10.1016/j.gene.2006.12.014
https://doi.org/10.1016/j.gene.2006.12.014
Autor:
Ken Yamada, Hyi-Man Park, Dean F Rigel, Keith DiPetrillo, Erin J Whalen, Anthony Anisowicz, Michael Beil, James Berstler, Cara Emily Brocklehurst, Debra A Burdick, Shari L Caplan, Michael P Capparelli, Guanjing Chen, Wei Chen, Bethany Dale, Lin Deng, Fumin Fu, Norio Hamamatsu, Kouki Harasaki, Tracey Herr, Peter Hoffmann, Qi-Ying Hu, Waan-Jeng Huang, Neeraja Idamakanti, Hidetomo Imase, Yuki Iwaki, Monish Jain, Jey Jeyaseelan, Mitsunori Kato, Virendar K Kaushik, Darcy Kohls, Vidya Kunjathoor, Daniel LaSala, Jongchan Lee, Jing Liu, Yang Luo, Fupeng Ma, Ruowei Mo, Sarah Mowbray, Muneto Mogi, Flavio Ossola, Pramod Pandey, Sejal J Patel, Swetha Raghavan, Bahaa Salem, Yuka H Shanado, Gary M Trakshel, Gordon Turner, Hiromichi Wakai, Chunhua Wang, Stephen Weldon, Jennifer B Wielicki, Xiaoling Xie, Lingfei Xu, Yukiko I Yagi, Kayo Yasoshima, Jianning Yin, David Yowe, Ji-Hu Zhang, Gang Zheng, Lauren Monovich
Publikováno v:
Nature chemical biology. 12(11)
The With-No-Lysine (K) (WNK) kinases play a critical role in blood pressure regulation and body fluid and electrolyte homeostasis. Herein, we introduce the first orally bioavailable pan-WNK-kinase inhibitor, WNK463, that exploits unique structural fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78087a9853125909a6b388fbc86c95c9
https://pubmed.ncbi.nlm.nih.gov/27595330
https://pubmed.ncbi.nlm.nih.gov/27595330
Autor:
Robert R. Recker, Colleen Folz, Mark Osborne, Richard G. Del Mastro, Arturo Morales, Nia Tzellas, Gordon Gong, Josée Dupuis, Susan P. Manning, Xintong Hu, Linda Chee, Craig Tulig, Anthony Anisowicz, Brenda K. Eustace, Alicia Bawa, Xavier Nogués, John P. Carulli, Susan Zweier, Kristina Allen, Shan Chuan Zhao, Michael Fitzgerald, Ronald Adair, Shannon M. McGuire, Peter T. Lomedico, Paul Van Eerdewegh, Pamela Marie Swain, Susan M. Recker, Anthony Caruso, Youssef Benchekroun, Karen Braunschweiger, Barbara Franklin, Randall D. Little, Michelle M. Lappe, Lia Spitzer, Mark L. Johnson
Publikováno v:
The American Journal of Human Genetics. 70(1):11-19
Osteoporosis is a complex disease that affects >10 million people in the United States and results in 1.5 million fractures annually. In addition, the high prevalence of osteopenia (low bone mass) in the general population places a large number of pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea53df4eaf6ec9e790a9c731ce54cc0f
Publikováno v:
Molecular Medicine. 8:42-55
We sought to identify genes with altered expression during human breast cancer progression by applying mRNA comparisons of normal and tumor mammary cell lines with increasingly malignant phenotypes. The gene encoding a new sialyltransferase (STM) was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fd377987527f1175c463db2e7cf8cdb
https://doi.org/10.1007/bf03402002
https://doi.org/10.1007/bf03402002
Publikováno v:
Molecular Medicine. 5:526-541
BACKGROUND: Invasive tumor cells are characterized by multiple phenotypic changes as a result of the large number of cDNAs being differentially expressed in tumor cells compared to normal progenitors. Expression genetics focuses on changes at the RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98fae42aab34dbd294412a39e48a0ff
https://doi.org/10.1007/bf03401980
https://doi.org/10.1007/bf03401980
Publikováno v:
Journal of Biological Chemistry. 272:903-910
A novel human cystatin gene was identified in a differential display comparison aimed at the isolation of transcriptionally regulated genes involved in invasion and metastasis of breast cancer. Messenger RNAs from primary and metastatic tumor cells i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d42fd6379feb37687504b60a5fab37f
https://doi.org/10.1074/jbc.272.2.903
https://doi.org/10.1074/jbc.272.2.903
Publikováno v:
Molecular Medicine. 2:624-636
Using differential display (DD), we discovered a new member of the serine protease family of protein-cleaving enzymes, named protease M. The gene is most closely related by sequence to the kallikreins, to prostate-specific antigen (PSA), and to tryps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2325e3d2149242fc6368987fcb1b3fc6
https://doi.org/10.1007/bf03401646
https://doi.org/10.1007/bf03401646
Publikováno v:
The FASEB Journal. 7:964-970
A new method of differential expression cloning called differential display (DD) has been used to screen for novel tumor suppressor genes involved in breast cancer. The screen is based on positive selection at the mRNA level for genes expressed in no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61662cb7068206b927e90d89c9a920a7
https://doi.org/10.1096/fasebj.7.10.8344495
https://doi.org/10.1096/fasebj.7.10.8344495
A high-throughput and sensitive method to measure global DNA methylation: application in lung cancer
Autor:
Pierre P. Massion, Heidi Giese, Richard G. Del Mastro, Huajun Wang, Jerzy Olejnik, Karen Braunschweiger, Hui Huang, Ziying Liu, Sergey Mamaev, Anthony Anisowicz
Publikováno v:
BMC Cancer
BMC Cancer, Vol 8, Iss 1, p 222 (2008)
BMC Cancer, Vol 8, Iss 1, p 222 (2008)
Background Genome-wide changes in DNA methylation are an epigenetic phenomenon that can lead to the development of disease. The study of global DNA methylation utilizes technology that requires both expensive equipment and highly specialized skill se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a2706d23988dd5a3c1fbffd1adb7d0
https://pubmed.ncbi.nlm.nih.gov/18673580
https://pubmed.ncbi.nlm.nih.gov/18673580
Autor:
Anthony Anisowicz, Shijie Sheng, Kristina Rafidi, Mary J.C. Hendrix, Zhiqiang Zou, Mark Joseph Neveu, Elisabeth A. Seftor, Ann D. Thor, Ruth Sager
Publikováno v:
Science (New York, N.Y.). 263(5146)
A gene encoding a protein related to the serpin family of protease inhibitors was identified as a candidate tumor suppressor gene that may play a role in human breast cancer. The gene product, called maspin, is expressed in normal mammary epithelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a46b12992d147a96856ba390ce974a
https://pubmed.ncbi.nlm.nih.gov/8091216
https://pubmed.ncbi.nlm.nih.gov/8091216