Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anthony Abbruscato"'
Autor:
Amel Karaa, Enrico Bertini, Valerio Carelli, Bruce Cohen, Gregory M. Ennes, Marni J. Falk, Amy Goldstein, Gráinne Gorman, Richard Haas, Michio Hirano, Thomas Klopstock, Mary Kay Koenig, Cornelia Kornblum, Costanza Lamperti, Anna Lehman, Nicola Longo, Maria Judit Molnar, Sumit Parikh, Han Phan, Robert D. S. Pitceathly, Russekk Saneto, Fernando Scaglia, Serenella Servidei, Mark Tarnopolsky, Antonio Toscano, Johan L. K. Van Hove, John Vissing, Jerry Vockley, Jeffrey S. Finman, Anthony Abbruscato, David A. Brown, Alana Sullivan, James A. Shiffer, Michelango Mancuso, on behalf of the MMPOWER-3 Trial Investigators
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background As previously published, the MMPOWER-3 clinical trial did not demonstrate a significant benefit of elamipretide treatment in a genotypically diverse population of adults with primary mitochondrial myopathy (PMM). However, the pres
Externí odkaz:
https://doaj.org/article/9ee65de424ba47d7a85aadc248d7ce12
Autor:
Justis P. Ehlers, MD, Allen Hu, MD, David Boyer, MD, Scott W. Cousins, MD, Nadia K. Waheed, MD, Philip J. Rosenfeld, MD, PhD, David Brown, MD, Peter K. Kaiser, MD, Anthony Abbruscato, PharmD, Gui Gao, PhD, Jeffrey Heier, MD, Prema Abraham, Christopher Devine, Anita Schadlu, George Novalis, Derek Y. Kunimoto, John Parchue, Suk Jin Moon, Zachary Segal, Dennis Marcus, Paul Hahn, Eric Suan, Michael Lee, Victor Gonzalez, Michael A. Samuel, Sunil Patel, Patrick Williams, Brian B. Berger, Henry Kwong, Dante Pieramici, Eric W. Schneider, Yevgeniy Shildkrot, Mathew T. Witmer, Nathan Steinle, Carmelina Gordon, Daniel Learned, Patrick Higgins, Guruprasad Pattar, Vijay Khetpal, Robin Ross, Mark R. Barakat, Sun Young Lee Sjatkowski, David Lally, Troy Becker
Publikováno v:
Ophthalmology Science, Vol 5, Iss 1, Pp 100628- (2025)
Objective: This study evaluated the safety and efficacy of elamipretide in dry age-related macular degeneration (AMD) with noncentral geographic atrophy (GA). Design: ReCLAIM-2 was a prospective, phase II, randomized, placebo-controlled, double-maske
Externí odkaz:
https://doaj.org/article/7164fb5412894bafbf1cb11d512f531f
Autor:
Brittany Hornby, William Reid Thompson, Mohammed Almuqbil, Ryan Manuel, Anthony Abbruscato, Jim Carr, Hilary J. Vernon
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-9 (2022)
Abstract Background Natural history studies are increasingly recognized as having an important role in drug development for rare diseases. A phase 3, observational, retrospective, and non-interventional study was designed to establish a natural histo
Externí odkaz:
https://doaj.org/article/e8832bd27a77474bb0ff3589b829e888
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100008- (2023)
Externí odkaz:
https://doaj.org/article/0cad6fe034604c7aaacbf9f0ab476cf9
Autor:
Alana Sullivan, Sandrin Bergheanu, Laura Kropp, Li Zhang, Benjamin McNeil, Lisa Beck, Anthony Abbruscato
Background and Purpose: Elamipretide is a mitochondrial-targeting agent being developed for the treatment of mitochondrial dysfunction-associated diseases. While prior studies have shown that subcutaneous elamipretide is generally safe/well tolerated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10912d6c6fcd24cefb6a9dd6914a6704
https://doi.org/10.22541/au.168075727.77826241/v1
https://doi.org/10.22541/au.168075727.77826241/v1
Autor:
Brittany Hornby, William Reid Thompson, Mohammed Almuqbil, Ryan Manuel, Anthony Abbruscato, Jim Carr, Hilary J. Vernon
Publikováno v:
Orphanet journal of rare diseases. 17(1)
Background Natural history studies are increasingly recognized as having an important role in drug development for rare diseases. A phase 3, observational, retrospective, and non-interventional study was designed to establish a natural history contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0044b821c33556f38193d7d0f9fffeb7
https://pubmed.ncbi.nlm.nih.gov/36056411
https://pubmed.ncbi.nlm.nih.gov/36056411
Autor:
Marcus P. J. van Diemen, Anthony Abbruscato, Geert Jan Groeneveld, Jeroen van der Grond, Pieter W Hameeteman, Sandrin C. Bergheanu, Hermien E. Kan, Emma M. Coppen, Liz Mead, Ilse van Beelen, Ellen P. Hart, Matthijs Moerland, Jessica Y. Winder, Andrew G. Webb, Raymund A.C. Roos
Publikováno v:
British Journal of Clinical Pharmacology, 87, 2290-2302. WILEY
British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology
Aims Huntington's disease (HD) is a neurodegenerative disease with cognitive, motor and psychiatric symptoms. Toxic accumulation of misfolded mutant huntingtin protein induces mitochondrial dysfunction, leading to a bioenergetic insufficiency in neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63a36b656060794f99706f934c755c5
http://hdl.handle.net/1887/3184283
http://hdl.handle.net/1887/3184283
Autor:
Jim Carr, Brittany Hornby, W. Reid Thompson, Hilary J. Vernon, Ryan Manuel, Anthony Abbruscato
Publikováno v:
Journal of the American College of Cardiology. 77:575
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83cfa2bbd4a6935b13d26f0f22d18b3a
https://doi.org/10.1016/s0735-1097(21)01934-3
https://doi.org/10.1016/s0735-1097(21)01934-3