Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Anthony A. Armstrong"'
Autor:
Lauren E. Boucher, Elisabeth Geyer Prinslow, Michael Feldkamp, Fang Yi, Rupesh Nanjunda, Sheng-Jiun Wu, Tun Liu, Eilyn R. Lacy, Steven Jacobs, Natalia Kozlyuk, Brian Del Rosario, Bingyuan Wu, Patricia Aquino, Robert C. Davidson, Samantha Heyne, Nicholas Mazzanti, James Testa, Michael D. Diem, Elsa Gorre, Andrew Mahan, Hirsh Nanda, Harsha P. Gunawardena, Alexis Gervais, Anthony A. Armstrong, Alexey Teplyakov, Chichi Huang, Adam Zwolak, Partha Chowdhury, Wan Cheung Cheung, Jinquan Luo
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTSingle-chain fragment variable (scFv) domains play an important role in antibody-based therapeutic modalities, such as bispecifics, multispecifics and chimeric antigen receptor T cells or natural killer cells. However, scFv domains exhibit lo
Externí odkaz:
https://doaj.org/article/07a49e5767d741f0bc24b50e3af689e1
Autor:
Adam Zwolak, Szeman Ruby Chan, Paul Harvilla, Sally Mahady, Anthony A. Armstrong, Leopoldo Luistro, Ninkka Tamot, Douglas Yamada, Mehabaw Derebe, Steven Pomerantz, Mark Chiu, Rajkumar Ganesan, Partha Chowdhury
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract TL1A (TNFSF15) is a TNF superfamily ligand which can bind the TNFRSF member death receptor 3 (DR3) on T cells and the soluble decoy receptor DcR3. Engagement of DR3 on CD4+ or CD8+ effector T cells by TL1A induces downstream signaling, leadi
Externí odkaz:
https://doaj.org/article/08da83cacee8430d962876b194440306
Autor:
Peng Zhang, Alice L. Kwon, Christina Guzzo, Qingbo Liu, Hana Schmeisser, Huiyi Miao, Yin Lin, Raffaello Cimbro, Jinghe Huang, Mark Connors, Stephen D. Schmidt, Michael A. Dolan, Anthony A. Armstrong, Paolo Lusso
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Elucidating the structure and function of the HIV-1 outer envelope proteins is critical for the design of an effective vaccine. Despite the availability of many high-resolution structures, key functional correlates in the envelope trimer remain undef
Externí odkaz:
https://doaj.org/article/b7ce808852144799b0fcfef045f0734b
Autor:
Aran F. Labrijn, Joyce I. Meesters, Matthew Bunce, Anthony A. Armstrong, Sandeep Somani, Tom C. Nesspor, Mark L. Chiu, Işil Altintaş, Sandra Verploegen, Janine Schuurman, Paul W. H. I. Parren
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Therapeutic concepts exploiting tumor-specific antibodies are often established in pre-clinical xenograft models using immuno-deficient mice. More complex therapeutic paradigms, however, warrant the use of immuno-competent mice, that more ac
Externí odkaz:
https://doaj.org/article/bbef8d706f08451bb51dc1be0939cbc2
Autor:
Susan H. Tam, Stephen G. McCarthy, Anthony A. Armstrong, Sandeep Somani, Sheng-Jiun Wu, Xuesong Liu, Alexis Gervais, Robin Ernst, Dorina Saro, Rose Decker, Jinquan Luo, Gary L. Gilliland, Mark L. Chiu, Bernard J. Scallon
Publikováno v:
Antibodies, Vol 6, Iss 3, p 12 (2017)
Engineering of fragment crystallizable (Fc) domains of therapeutic immunoglobulin (IgG) antibodies to eliminate their immune effector functions while retaining other Fc characteristics has numerous applications, including blocking antigens on Fc gamm
Externí odkaz:
https://doaj.org/article/e4effcd57176409f88ce8c9b266a42aa
Autor:
Fredy Nehme, Anthony E. Armstrong, Mehran Taherian, Patrick M. Lynch, David M. Richards, Deanndra N. Casanova, Phillip S. Ge
Publikováno v:
VideoGIE. 8:96-99
Autor:
Travis J. Bourret, Laura S. Hall, Anthony A. Armstrong, William K. Boyle, Frank C. Gherardini, Daniel P. Dulebohn, D. Scott Samuels
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
The Lyme disease spirochete Borrelia burgdorferi exhibits dramatic changes in gene expression as it transits between its tick vector and vertebrate host. A major hurdle to understanding the mechanisms underlying gene regulation in B. burgdorferi has
Autor:
Anthony Robert Armstrong, Daniel N. Rainer, Atin Pramanik, Joel M. Cabañero, Russell E. Morris, Aamod V. Desai
Publikováno v:
Small methods. 5(12)
This work was supported by the Faraday Institution (Grant number—FIRG018). The authors also acknowledge the Engineering and Physical Sciences Research Council (EPSRC) Light Element Facility Grant (EP/T019298/1) and the EPSRC Strategic Equipment Res
Autor:
Chih-Hsiang Chien, Kashif Nawaz, Meng-Dawn Cheng, Im Piljae, Brian A. Fricke, Anthony Q. Armstrong
To simulate the exposure potential of infectious aerosol such as SARS-CoV-2 in an office building setting, experimental studies for airborne particle transmission have been conducted in a model commercial office building at the Oak Ridge National Lab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fa0e2393ef48996c54f10486cef947e
https://doi.org/10.1101/2021.02.25.21252239
https://doi.org/10.1101/2021.02.25.21252239