Zobrazeno 1 - 10
of 388
pro vyhledávání: '"Anthony A Grace"'
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 5, Pp 100338- (2024)
Background: Psychiatric disorders often emerge during late adolescence/early adulthood, a period with increased susceptibility to socioenvironmental factors that coincides with incomplete parvalbumin interneuron (PVI) development. Stress during this
Externí odkaz:
https://doaj.org/article/1161424f3a58432f8a39d8a5cef49ecd
Autor:
Jonathan Savitz, Colin A Hodgkinson, Chantal Martin-Soelch, Pei-Hong Shen, Joanna Szczepanik, Allison Nugent, Peter Herscovitch, Anthony A Grace, David Goldman, Wayne C Drevets
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54108 (2013)
Abnormalities of motivation and behavior in the context of reward are a fundamental component of addiction and mood disorders. Here we test the effect of a functional missense mutation in the dopamine 3 receptor (DRD3) gene (ser9gly, rs6280) on rewar
Externí odkaz:
https://doaj.org/article/9daed35fa3314d38a4c766dcb30ef9dd
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e49732 (2012)
The tremendous advances in understanding the neurobiological circuits involved in schizophrenia have not translated into more effective treatments. An alternative strategy is to use a recently published 'Quantitative Systems Pharmacology' computer-ba
Externí odkaz:
https://doaj.org/article/d6a10b6d2079407a9454f13ab5070da1
Autor:
Samuel Knight, Robert McCutcheon, Daniella Dwir, Anthony A. Grace, Owen O’Daly, Philip McGuire, Gemma Modinos
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Despite strong evidence of the neurodevelopmental origins of psychosis, current pharmacological treatment is not usually initiated until after a clinical diagnosis is made, and is focussed on antagonising striatal dopamine receptors. These d
Externí odkaz:
https://doaj.org/article/1204fab960124f88b950605a14a96fe6
Autor:
Millie Rincón-Cortés, Anthony A. Grace
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Postpartum depression (PPD) is the most common psychiatric disorder following childbirth and is characterized by maternal mood disturbances, impaired maternal responses, and disrupted caregiving- all of which negatively impact offspring development.
Externí odkaz:
https://doaj.org/article/7bd4c4ae265f4db8843689416849880f
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Animal models of psychiatric disorders have been highly effective in advancing the field, identifying circuits related to pathophysiology, and identifying novel therapeutic targets. In this review, we show how animal models, particularly those based
Externí odkaz:
https://doaj.org/article/36e93888c10f4638a1ffd0a02fdffdbb
Autor:
Millie Rincón-Cortés, Anthony A. Grace
Publikováno v:
Frontiers in Global Women's Health, Vol 2 (2021)
Offspring interaction is among the most highly motivated behaviors in maternal mammals and is mediated by mesolimbic dopamine (DA) system activation. Disruption or loss of significant social relationships is among the strongest individual predictors
Externí odkaz:
https://doaj.org/article/f0e685a65b2245e1acc00cca44d70008
Autor:
Samuel Knight, Robert McCutcheon, Daniella Dwir, Anthony A. Grace, Owen O’Daly, Philip McGuire, Gemma Modinos
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/7430216d60004bf2a7b49d4082f62e0f
Publikováno v:
Current Opinion in Psychiatry. 36:172-178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::358fe6235da5166d3dc42a2dfc0318ba
https://doi.org/10.1097/yco.0000000000000854
https://doi.org/10.1097/yco.0000000000000854
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Dysregulation of the dopamine system is central to many models of the pathophysiology of psychosis in schizophrenia. However, emerging evidence suggests that this dysregulation is driven by the disruption of upstream circuits that provide afferent co
Externí odkaz:
https://doaj.org/article/c7c8787f711d449c813c87ac66fa15f3