Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anthony Tuesca"'
Autor:
Feng Chen, Kai Ma, Brian Madajewski, Li Zhuang, Li Zhang, Keith Rickert, Marcello Marelli, Barney Yoo, Melik Z. Turker, Michael Overholtzer, Thomas P. Quinn, Mithat Gonen, Pat Zanzonico, Anthony Tuesca, Michael A. Bowen, Larry Norton, J. Anand Subramony, Ulrich Wiesner, Michelle S. Bradbury
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
One of the major obstacles in nanoparticle-based therapy is to achieve tumour targeting, limiting non-specific accumulation of the nanoparticles. Here the authors propose the conjugation of anti-HER2 scFv fragments to the silica nanoparticles, increa
Externí odkaz:
https://doaj.org/article/d095ee381fd844ee881d6637c08ac110
Autor:
Rohan Fernandes, Anthony Tuesca, Raymond W. Sze, Shraddha S Kale, J. Anand Subramony, Zungho Zun, Elizabeth E. Sweeney, Rachel A. Burga
Publikováno v:
International Journal of Nanomedicine. 12:6413-6424
Theranostic nanoparticles offer the potential for mixing and matching disparate diagnostic and therapeutic functionalities within a single nanoparticle for the personalized treatment of diseases. In this article, we present composite iron oxide-gadol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88b3906ffa09e065fd1664daaf3a7e7b
https://doi.org/10.2147/ijn.s144515
https://doi.org/10.2147/ijn.s144515
Autor:
Li Zhuang, Feng Chen, Michael Overholtzer, Larry Norton, Marcello Marelli, Anthony Tuesca, Thomas P. Quinn, Pat Zanzonico, Michelle S. Bradbury, Li Zhang, Barney Yoo, Ulrich Wiesner, Keith W Rickert, Mithat Gonen, Michael A. Bowen, Melik Z. Turker, J. Anand Subramony, Kai Ma, Brian Madajewski
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Controlling the biodistribution of nanoparticles upon intravenous injection is the key to achieving target specificity. One of the impediments in nanoparticle-based tumor targeting is the inability to limit the trafficking of nanoparticles to liver a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a2072dd9a4444d359d1e39f43059fa
https://pubmed.ncbi.nlm.nih.gov/30297810
https://pubmed.ncbi.nlm.nih.gov/30297810
Autor:
Anthony M. Lowman, Mariko Morishita, Koji Nakamura, Nicholas A. Peppas, Anthony Tuesca, Jeffrey I. Joseph
Publikováno v:
Journal of Pharmaceutical Sciences. 97:2607-2618
Hydrogels comprised of poly(methacrylic acid) grafted with poly(ethylene glycol) (P(MAA-g-EG)) were characterized and examined for their potential as oral insulin carriers. Insulin loaded polymer (ILP) samples were made using two different polymer fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90461fb5b1520fbf2d85930943f23bea
https://doi.org/10.1002/jps.21184
https://doi.org/10.1002/jps.21184
Autor:
Anthony M. Lowman, Anthony Tuesca
Publikováno v:
Macromolecular Symposia. 266:101-107
Environmentally responsive hydrogels composed of poly(methacrylic acid-g-ethylene glycol) (P(MAA-g-EG)) have shown promise for oral insulin delivery due to their pH responsive complexation behavior. A series of hydrogel formulations were polymerized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2356faedaf8d657ca22c38cb0c487cf3
https://doi.org/10.1002/masy.200850619
https://doi.org/10.1002/masy.200850619
Publikováno v:
Journal of Biomaterials Science, Polymer Edition. 18:1475-1490
The insulin-transport enhancing effects of a pH-sensitive poly((methacrylic acid)-grafted-poly(ethylene glycol)) hydrogel system were studied using Caco-2 monolayers as an in vitro model of intestinal transport. Further, the ability of the hydrogel s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::847feced30234ac5ef08cde51e1aa046
https://doi.org/10.1163/156856207794761989
https://doi.org/10.1163/156856207794761989
Publikováno v:
Pharmaceutical research. 26(3)
This work evaluated the feasibility of combining insulin PEGylation with pH responsive hydrogels for oral insulin delivery. A mono-substituted PEG–insulin conjugate was synthesized and purified. The site of conjugation was determined by MALDI-TOF M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d70ff7d4ba958ef9f8f73a43b9a842
https://pubmed.ncbi.nlm.nih.gov/19145407
https://pubmed.ncbi.nlm.nih.gov/19145407
Publikováno v:
Pharmaceutical Research; Mar2009, Vol. 26 Issue 3, p727-739, 13p