Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Anthony J. Wilkinson"'
Autor:
Nathaniel G. Jones, Vincent Geoghegan, Gareth Moore, Juliana B. T. Carnielli, Katherine Newling, Félix Calderón, Raquel Gabarró, Julio Martín, Rab K. Prinjha, Inmaculada Rioja, Anthony J. Wilkinson, Jeremy C. Mottram
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Leishmania use large (5–10 kb) transcriptional start regions, where the chromatin is highly enriched for acetylated histones, to drive the expression of polycistronic gene arrays. Here the authors show bromodomain-containing protein BDF5 is enriche
Externí odkaz:
https://doaj.org/article/1db1b17d7f85497d9117d4a2f66ff272
Commonality of Virulence-Promoting Function in Rhodococcus equi Virulence Associated Proteins (Vaps)
Autor:
Timothy R. Ganderton, Daniel Ghete, Karen Hogg, Graeme J. Park, Christoph G. Baumann, Anthony J. Wilkinson, Paul R. Pryor
Publikováno v:
Cellular Microbiology, Vol 2023 (2023)
Rhodococcus equi is a Gram-positive facultative intracellular pathogen associated with life-threatening bronchopneumonial disease in foals. Key to R. equi’s intracellular survival in host macrophages is the production of virulence associated protei
Externí odkaz:
https://doaj.org/article/8fcd257f6fda4e5aab30745b6d0771a3
Autor:
Adam J.M. Wollman, Katarína Muchová, Zuzana Chromiková, Anthony J. Wilkinson, Imrich Barák, Mark C. Leake
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1474-1486 (2020)
Here we use singe-molecule optical proteomics and computational analysis of live cell bacterial images, using millisecond super-resolved tracking and quantification of fluorescently labelled protein SpoIIE in single live Bacillus subtilis bacteria to
Externí odkaz:
https://doaj.org/article/a04443fb495b4d399f39519f4d34d355
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008784 (2020)
Post-translational modifications such as ubiquitination are important for orchestrating the cellular transformations that occur as the Leishmania parasite differentiates between its main morphological forms, the promastigote and amastigote. 2 E1 ubiq
Externí odkaz:
https://doaj.org/article/69b78755285242c4a73c13a659ddbd34
Autor:
Nadine Daou, Yuanguo Wang, Vladimir M Levdikov, Madhumitha Nandakumar, Jonathan Livny, Laurent Bouillaut, Elena Blagova, Keshan Zhang, Boris R Belitsky, Kyu Rhee, Anthony J Wilkinson, Xingmin Sun, Abraham L Sonenshein
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0206896 (2019)
Toxin synthesis and endospore formation are two of the most critical factors that determine the outcome of infection by Clostridioides difficile. The two major toxins, TcdA and TcdB, are the principal factors causing damage to the host. Spores are th
Externí odkaz:
https://doaj.org/article/88f5ccc2c5a14f20a04ef83f1d228a62
Autor:
Adam M. Hughes, John F. Darby, Eleanor J. Dodson, Samuel J. Wilson, Johan P. Turkenburg, Gavin H. Thomas, Anthony J. Wilkinson
Publikováno v:
Microbiology. 168
Peptide transporters play important nutritional and cell signalling roles in Bacillus subtilis, which are pronounced during stationary phase adaptations and development. Three high-affinity ATP-binding cassette (ABC) family transporters are involved
Autor:
Niels Bradshaw, Vladimir M Levdikov, Christina M Zimanyi, Rachelle Gaudet, Anthony J Wilkinson, Richard Losick
Publikováno v:
eLife, Vol 6 (2017)
PP2C phosphatases control biological processes including stress responses, development, and cell division in all kingdoms of life. Diverse regulatory domains adapt PP2C phosphatases to specific functions, but how these domains control phosphatase act
Externí odkaz:
https://doaj.org/article/de37c6a6b1a045ee8256d4e20a33bf48
Autor:
James A. Brannigan, Shirley M. Roberts, Andrew S. Bell, Jennie A. Hutton, Michael R. Hodgkinson, Edward W. Tate, Robin J. Leatherbarrow, Deborah F. Smith, Anthony J. Wilkinson
Publikováno v:
IUCrJ, Vol 1, Iss 4, Pp 250-260 (2014)
The leishmaniases are a spectrum of global diseases of poverty associated with immune dysfunction and are the cause of high morbidity. Despite the long history of these diseases, no effective vaccine is available and the currently used drugs are vari
Externí odkaz:
https://doaj.org/article/0ddbe1c7f7b94b29aa4a10083708bb2c
Autor:
Matthew T. G. Holden, Daniel Bawdon, Diana S. Cox, Anthony J. Wilkinson, Reyme Herman, Eleanor J. Dodson, Matthew Rose, Michelle Rudden, A. Gordon James, Gavin H. Thomas
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
This work was supported by the BBSRC Grant BB/N006615/1. Body odour is a characteristic trait of Homo sapiens, however its role in human behaviour and evolution is poorly understood. Remarkably, body odour is linked to the presence of a few species o
Autor:
Mark C. Leake, Anthony J. Wilkinson, Zuzana Chromiková, Imrich Barák, Katarína Muchová, Adam J. M. Wollman
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 1474-1486 (2020)
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 1474-1486 (2020)
Graphical abstract
Here we use singe-molecule optical proteomics and computational analysis of live cell bacterial images, using millisecond super-resolved tracking and quantification of fluorescently labelled protein SpoIIE in single live Bacil
Here we use singe-molecule optical proteomics and computational analysis of live cell bacterial images, using millisecond super-resolved tracking and quantification of fluorescently labelled protein SpoIIE in single live Bacil