Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Anthony J. Valentijn"'
Publikováno v:
Owens, T W, Foster, F M, Valentijn, A, Gilmore, A P & Streuli, C H 2010, ' Role for X-linked inhibitor of apoptosis protein upstream of mitochondrial permeabilization ', Journal of Biological Chemistry, vol. 285, no. 2, pp. 1081-1088 . https://doi.org/10.1074/jbc.M109.072322
The Journal of Biological Chemistry
The Journal of Biological Chemistry
Apoptosis is controlled by a signaling equilibrium between prosurvival and proapoptotic pathways, such that unwanted apoptosis is avoided, but when required it occurs rapidly and efficiently. Many apoptosis regulators display dual roles, depending up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6156f95cffdc169417cafdb93dce3eb0
https://doi.org/10.1074/jbc.m109.072322
https://doi.org/10.1074/jbc.m109.072322
Autor:
James A. Keeble, Charles H. Streuli, Jennefer Lindsay, Christopher E. Turner, Anthony J. Valentijn, Deborah Mills, Andrew P. Gilmore, Nadia K. Zouq, Lu Zhang
Publikováno v:
Journal of Cell Science. 122:357-367
Different cell types interpret their distinct extracellular matrix (ECM) environments to bring about specific cell fate decisions, and can differentiate or undergo apoptosis depending on their local adhesive interactions. Apoptosis in response to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798efbf5cc29a9bb6974e5324e4bafd3
https://doi.org/10.1242/jcs.030478
https://doi.org/10.1242/jcs.030478
Publikováno v:
Biochemical Journal. 412:347-357
Bax, a pro-apoptotic Bcl-2 family protein, translocates to mitochondria during apoptosis, where it causes MOMP (mitochondrial outer membrane permeabilization). MOMP releases pro-apoptotic factors, such as cytochrome c and SMAC (second mitochondrial a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689072b349b86774b99d8d2272c5150e
https://doi.org/10.1042/bj20071548
https://doi.org/10.1042/bj20071548
Publikováno v:
Cell Death & Differentiation. 14:932-942
The Bcl-2 protein Bax normally resides in the cytosol, but during apoptosis it translocates to mitochondria where it is responsible for releasing apoptogenic factors. Using anoikis as a model, we have shown that Bax translocation does not commit cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a91796e004b4fab1b0408a08515ee6
https://doi.org/10.1038/sj.cdd.4402092
https://doi.org/10.1038/sj.cdd.4402092
Publikováno v:
Journal of Biological Chemistry. 279:32848-32857
Epithelial cells require adhesion to the extracellular matrix for survival, and in the absence of adhesion they undergo apoptosis (anoikis). This is distinct from apoptosis induced by extracellular death ligands, such as tumor necrosis factor, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6249ea61b739255c852a188578666d3b
https://doi.org/10.1074/jbc.m313375200
https://doi.org/10.1074/jbc.m313375200
Autor:
Charles H. Streuli, Emma T. Lowe, Nasreen Akhtar, Steve Bagley, Anthony J. Valentijn, Ghada Zoubiane, Andrew P. Gilmore
Publikováno v:
Journal of Cell Science. 117:271-280
The function of exocrine glands depends on signals within the extracellular environment. In the mammary gland, integrin-mediated adhesion to the extracellular matrix protein laminin co-operates with soluble factors such as prolactin to regulate tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575f5d80cad8ee17d1f7b4c7b42d3046
https://doi.org/10.1242/jcs.00855
https://doi.org/10.1242/jcs.00855
Publikováno v:
The Journal of Cell Biology
Bax, a member of the Bcl-2 family, translocates to mitochondria during apoptosis, where it forms oligomers which are thought to release apoptogenic factors such as cytochrome c. Using anoikis as a model system, we have examined spatial and temporal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993b01515d1964d4b1735a14b1c46bad
https://doi.org/10.1083/jcb.200302154
https://doi.org/10.1083/jcb.200302154
Publikováno v:
Journal of Biological Chemistry. 278:19917-19925
Adhesion of many cell types to the extracellular matrix is essential to maintain their survival. In the absence of integrin-mediated signals, normal epithelial cells undergo a form of apoptosis termed anoikis. It has been proposed that the activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf666e8e411af91882f076db847c5ac5
https://doi.org/10.1074/jbc.m210337200
https://doi.org/10.1074/jbc.m210337200
Publikováno v:
Journal of Hypertension. 9:29-34
Rat kidney renin was purified 29,000-fold using a nine-step procedure with a 4% recovery. N-terminal sequence analysis of the non-reduced renin revealed two sequences, indicating a two-chain structure. When compared with the amino acid sequence deduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fedac20489eaee4475c4acb6026235a
https://doi.org/10.1097/00004872-199101000-00005
https://doi.org/10.1097/00004872-199101000-00005
Publikováno v:
Molecular and Cellular Endocrinology. 73:83-91
Rat renin fused at the N-terminus with Sj26, a 26,000 Da glutathione S-transferase of Schistosomajaponicum, was expressed in Escherichia coli. The fusion protein was soluble and easily purified from crude bacterial lysates by affinity chromatography
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e9b19498d5b8022c55cb65bc0ff64d
https://doi.org/10.1016/0303-7207(90)90121-n
https://doi.org/10.1016/0303-7207(90)90121-n