Zobrazeno 1 - 10
of 526
pro vyhledávání: '"Anthony, Watts"'
Autor:
Juan F. Bada Juarez, Peter J. Judge, Suliman Adam, Danny Axford, Javier Vinals, James Birch, Tristan O. C. Kwan, Kin Kuan Hoi, Hsin-Yung Yen, Anthony Vial, Pierre-Emmanuel Milhiet, Carol V. Robinson, Igor Schapiro, Isabel Moraes, Anthony Watts
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Archaerhodopsin-3 (AR3) mutants are commonly used in optogenetics for neuron silencing and membrane voltage sensing. High-resolution crystal structures show that desensitization of the AR3 photoreceptor occurs when internal hydrogen-bonded water netw
Externí odkaz:
https://doaj.org/article/039fb047d8d74a55a61854b573e871d6
Publikováno v:
European Biophysics Journal. 52:39-51
From the discovery of the first membrane-interacting polymer, styrene maleic-acid (SMA), there has been a rapid development of membrane solubilising polymers. These new polymers can solubilise membranes under a wide range of conditions and produce va
Publikováno v:
Geochemistry, Geophysics, Geosystems, Vol 21, Iss 2, Pp n/a-n/a (2020)
Abstract The rheology of oceanic lithosphere is important to our understanding of mantle dynamics and to the emergence and manifestations of plate tectonics. Data from experimental rock mechanics suggest rheology is dominated by three different defor
Externí odkaz:
https://doaj.org/article/e9ca7ba5594248b084fda9a494bd81a4
Autor:
Patricia M. Dijkman, Oliver K. Castell, Alan D. Goddard, Juan C. Munoz-Garcia, Chris de Graaf, Mark I. Wallace, Anthony Watts
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Evidence suggests oligomerisation of G protein-coupled receptors in membranes, but this is controversial. Here, authors use single-molecule and ensemble FRET, and spectroscopy to show that the neurotensin receptor 1 forms multiple dimer conformations
Externí odkaz:
https://doaj.org/article/28f2d38675864c7fa3f3f5c8d36e8dc1
Autor:
Danny Axford, Peter J. Judge, Juan F. Bada Juarez, Tristan O. C. Kwan, James Birch, Javier Vinals, Anthony Watts, Isabel Moraes
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
High-resolution X-ray diffraction data were collected at room temperature for light- and dark-adapted states of the archaerhodopsin-3 photoreceptor using transparent and opaque polymer-film sample mounts.
Room-temperature diffraction methods are
Room-temperature diffraction methods are
Publikováno v:
Journal of the American Chemical Society. 144(48)
Bacteriorhodopsin (bR) is a light-driven microbial receptor, and lysine 159 (K159) is a charged residue on the cytoplasmic (CP) side of its E-F loop. However, its conformation and function remain unknown due to fast surface dynamics. By utilizing a
Publikováno v:
Geophysical Journal International. 228:857-875
SUMMARY Recent modelling studies have shown that laboratory-derived rheology is too strong to reproduce observations of flexure at the Hawaiian Islands, while the same rheology appears consistent with outer rise—trench flexure at circum-Pacific sub
Publikováno v:
Royal Society Open Science, Vol 4, Iss 3 (2017)
Our understanding of animal flight benefits greatly from specialized wind tunnels designed for flying animals. Existing facilities can simulate laminar flow during straight, ascending and descending flight, as well as at different altitudes. However,
Externí odkaz:
https://doaj.org/article/fc9e77c866f2452b93e55d47a5f9f964
Autor:
Jesús Pérez-Gil, Anthony Watts
Publikováno v:
Biophysical Reviews
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 6913
S-TGA-1 and PGP-Me are native archaeal lipids associated with the bacteriorhodopsin (bR) trimer and contribute to protein stabilization and native dynamics for proton transfer. However, little is known about the underlying molecular mechanism of how