Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anthony, Venida"'
Autor:
Rushika M. Perera, Gina M. DeNicola, Yin Shen, Joseph D. Mancias, Andrew J. Aguirre, Isha H. Jain, Zeynep Cakir, Annelot A.L. Staes, Gilles Rademaker, Brandon R. Desousa, Yang Yang, Connor J. Hennessey, Annan Yang, Miljan Kuljanin, Callum Foakes, Anthony Venida, Nathan P. Ward, Charles Cai, Jingjie Hu, Mirunalini Ravichandran
Supplementary Figure from Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS–MAPK Pathway Inhibition in Pancreatic Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008fc08e6a6d30e00e13939c165ffabb
https://doi.org/10.1158/2159-8290.22541245
https://doi.org/10.1158/2159-8290.22541245
Autor:
Rushika M. Perera, Gina M. DeNicola, Yin Shen, Joseph D. Mancias, Andrew J. Aguirre, Isha H. Jain, Zeynep Cakir, Annelot A.L. Staes, Gilles Rademaker, Brandon R. Desousa, Yang Yang, Connor J. Hennessey, Annan Yang, Miljan Kuljanin, Callum Foakes, Anthony Venida, Nathan P. Ward, Charles Cai, Jingjie Hu, Mirunalini Ravichandran
The mechanisms underlying metabolic adaptation of pancreatic ductal adenocarcinoma (PDA) cells to pharmacologic inhibition of RAS–MAPK signaling are largely unknown. Using transcriptome and chromatin immunoprecipitation profiling of PDA cells treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b3833f5d5e817029afb1104f29c145
https://doi.org/10.1158/2159-8290.c.6549586
https://doi.org/10.1158/2159-8290.c.6549586
Autor:
Rushika M. Perera, Gina M. DeNicola, Yin Shen, Joseph D. Mancias, Andrew J. Aguirre, Isha H. Jain, Zeynep Cakir, Annelot A.L. Staes, Gilles Rademaker, Brandon R. Desousa, Yang Yang, Connor J. Hennessey, Annan Yang, Miljan Kuljanin, Callum Foakes, Anthony Venida, Nathan P. Ward, Charles Cai, Jingjie Hu, Mirunalini Ravichandran
Supplementary Data from Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS–MAPK Pathway Inhibition in Pancreatic Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0290b212d1d8e5dc56820f5ed9266839
https://doi.org/10.1158/2159-8290.22541248.v1
https://doi.org/10.1158/2159-8290.22541248.v1
Autor:
Mirunalini Ravichandran, Jingjie Hu, Charles Cai, Nathan P. Ward, Anthony Venida, Callum Foakes, Miljan Kuljanin, Annan Yang, Connor J. Hennessey, Yang Yang, Brandon R. Desousa, Gilles Rademaker, Annelot A.L. Staes, Zeynep Cakir, Isha H. Jain, Andrew J. Aguirre, Joseph D. Mancias, Yin Shen, Gina M. DeNicola, Rushika M. Perera
Publikováno v:
Cancer discovery, vol 12, iss 9
Cancer Discov
Cancer Discov
The mechanisms underlying metabolic adaptation of pancreatic ductal adenocarcinoma (PDA) cells to pharmacologic inhibition of RAS–MAPK signaling are largely unknown. Using transcriptome and chromatin immunoprecipitation profiling of PDA cells treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274d86e2bf3445d5469fa88c7f1ba96a
https://escholarship.org/uc/item/0qm115km
https://escholarship.org/uc/item/0qm115km
Autor:
Matthew H. Spitzer, Breanna M. Allen, Kamir J. Hiam, Yaron Carmi, Anthony Venida, Iliana Tenvooren, Nam Woo Cho, Diana M. Marquez, Rachel DeBarge, Cassandra E. Burnett
Publikováno v:
Nature medicine, vol 26, iss 7
Understanding of the factors governing immune responses in cancer remains incomplete, limiting patient benefit. In this study, we used mass cytometry to define the systemic immune landscape in response to tumor development across five tissues in eigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edac9402d0a8d3ac07a217ae4e100d10
https://escholarship.org/uc/item/9dj6r89z
https://escholarship.org/uc/item/9dj6r89z
Publikováno v:
Autophagy
Major histocompatibility complex class I (MHC-I) is a key molecule in anti-tumor adaptive immunity. MHC-I is essential for endogenous antigen presentation by cancer cells and subsequent recognition and clearance by CD8(+) T cells. Defects in MHC-I ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4783fdd736f5d1f781f12b53b1516059
https://doi.org/10.1080/15548627.2020.1769973
https://doi.org/10.1080/15548627.2020.1769973
Autor:
Rachel DeBarge, Yaron Carmi, Anthony Venida, Cassandra E. Burnett, Breanna M. Allen, Kamir J. Hiam, Matthew H. Spitzer
Harnessing immune defense mechanisms has revolutionized cancer therapy, but our understanding of the factors governing immune responses in cancer remains incomplete, limiting patient benefit. Here, we use mass cytometry to define the organism-wide im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ac0f1f693f427b45dfc09d4118b891
https://doi.org/10.1101/805473
https://doi.org/10.1101/805473
Autor:
Breanna M, Allen, Kamir J, Hiam, Cassandra E, Burnett, Anthony, Venida, Rachel, DeBarge, Iliana, Tenvooren, Diana M, Marquez, Nam Woo, Cho, Yaron, Carmi, Matthew H, Spitzer
Publikováno v:
Nature medicine. 26(7)
Understanding of the factors governing immune responses in cancer remains incomplete, limiting patient benefit. In this study, we used mass cytometry to define the systemic immune landscape in response to tumor development across five tissues in eigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52d402031cd0d3c8efe19848b5b8bd68
https://pubmed.ncbi.nlm.nih.gov/32620876
https://pubmed.ncbi.nlm.nih.gov/32620876
Autor:
Anthony Venida, Miwako Yamamoto-Kakiuchi, Doug E. Biancur, Rushika M. Perera, Alec C. Kimmelman, Albert P. Sohn, Keisuke Yamamoto
Publikováno v:
Cancer Research. 79:PR05-PR05
Pancreatic ductal adenocarcinoma (PDAC) is a deadly malignancy refractory to most therapies, including immune checkpoint blockade (ICB). Autophagy is a highly conserved self-degradation process that recycles cellular components. PDAC requires high le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5207c4a93e6ea956b7c2f4a64662cb2
https://doi.org/10.1158/1538-7445.panca19-pr05
https://doi.org/10.1158/1538-7445.panca19-pr05
Autor:
Ying Wang, Susan Price, Joshua J McElwee, Ahmet Ozen, Michael Richards, Isil Barlan, Anthony Venida, Matthew Biancalana, Jason D. Hughes, Morgan Butrick, Yu Zhang, Helen F. Matthews, Michael J. Lenardo, Tamara C. Pozos, Helen C. Su, Carrie L. Lucas, V. Koneti Rao, Xiaochuan Wang
Publikováno v:
The Journal of Experimental Medicine
Lucas et al. identify humans with a gain-of-function mutation in PIK3R1, encoding the p85α subunit of PI3K. The splice site mutation causes in-frame skipping of exon 11, resulting in altered p85α association with p110δ that stabilizes the catalyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e64dbc67a8f29215ca42773ba5255dc
https://doi.org/10.1084/jem.20141759
https://doi.org/10.1084/jem.20141759