Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Anthony, Varghese"'
Autor:
Abhimanyu Ghosh, William Kunkel, Anthony Varghese, Ying Ma, Rahul Gomes, Sudeep Bhattacharyya, Molly Mohr, Isabella Doss, Jordan Hebert
Publikováno v:
Proceedings of the 54th ACM Technical Symposium on Computer Science Education V. 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60321895dcdf3fbfa60a92800f7d63fc
https://doi.org/10.1145/3545945.3569784
https://doi.org/10.1145/3545945.3569784
Autor:
Anthony Varghese
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
The inwardly rectifying potassium current (IK1) and the fast inward sodium current (INa) are reciprocally modulated in mammalian ventricular myocytes. An increase in the expression of channels responsible for one of these two currents results in a co
Externí odkaz:
https://doaj.org/article/8d8a89095bc84921b088459d69f8a9b9
Autor:
Jane A. Bursill, Jamie I. Vandenberg, Martyn P. Mahaut-Smith, Christopher L.-H. Huang, Yu Lu, Anthony Varghese
Publikováno v:
American Journal of Physiology-Cell Physiology. 291:C165-C175
The function of voltage-gated human ether-à-go-gorelated gene ( hERG) K+ channels is critical for both normal cardiac repolarization and suppression of arrhythmias initiated by premature excitation. These important functions are facilitated by their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960046e85711a9f70143758a0271748c
https://doi.org/10.1152/ajpcell.00596.2005
https://doi.org/10.1152/ajpcell.00596.2005
Publikováno v:
Progress in Biophysics and Molecular Biology. 90:26-37
A transformed line of human embryonic kidney epithelial cells (HEK 293) is commonly used as an expression system for exogenous ion channel genes. Previously, it has been shown that these cells contain mRNAs for a variety of ion channels. Expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fcb3b27721d2a46bbce7762c3b1a2ff
https://doi.org/10.1016/j.pbiomolbio.2005.05.002
https://doi.org/10.1016/j.pbiomolbio.2005.05.002
Autor:
Jozef Murar, Daniel P. Nelson, E. Kenneth Weir, Rosemary F. Kelly, Irene M. Lang, Zhigang Hong, Anthony Varghese, Shahrzad Rezaie-Majd
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 287:R1209-R1213
Plasma levels of serotonin are elevated in primary pulmonary hypertension even after bilateral lung transplantation, suggesting a possible etiologic role. Serotonin is released primarily from the small intestine. Anorectic agents, such as dexfenflura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42554c692c90273acf227fade63cbe00
https://doi.org/10.1152/ajpregu.00191.2004
https://doi.org/10.1152/ajpregu.00191.2004
Autor:
Anthony Varghese
Publikováno v:
Biophysical Journal. 110(3):330a-331a
The main ion channels involved in the propagation of action potentials in cardiac cells are the voltage-gated sodium channels, the inward rectifier potassium channels, and the inter-cellular gap junction channels. Sodium channels have been shown to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66435ed319e63e20f2d7445fd0320150
Publikováno v:
Proceedings of the National Academy of Sciences. 100:10534-10539
HERG (human ether-a-go-go-related gene) encodes a delayed rectifier K + channel vital to normal repolarization of cardiac action potentials. Attenuation of repolarizing K + current caused by mutations in HERG or channel block by common medications pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c2fb11da5c95cf0542c78e637a2657
https://doi.org/10.1073/pnas.1832721100
https://doi.org/10.1073/pnas.1832721100
Autor:
E. Kenneth Weir, Daniel P. Nelson, Rosemary F. Kelly, Anthony Varghese, Zhigang Hong, Jozef Murar, Fangxiao Hong
Publikováno v:
The Annals of Thoracic Surgery. 75:1705-1710
Background Low potassium dextran lung preservation solution has reduced primary graft failure in animal and human studies. Though the mechanism of reducing primary graft failure is unknown, low potassium dextran differs most significantly from soluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c40eb62d48a875c32791520d430be5
https://doi.org/10.1016/s0003-4975(03)00173-5
https://doi.org/10.1016/s0003-4975(03)00173-5
Autor:
Anthony Varghese, Linda M. Boland
Publikováno v:
Journal of Computational Neuroscience. 12:123-137
The opening of voltage-gated sodium, potassium, and calcium ion channels has a steep relationship with voltage. In response to changes in the transmembrane voltage, structural movements of an ion channel that precede channel opening generate a capaci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1109c2267b01bd14bc7fd1623ec2af2c
https://doi.org/10.1023/a:1015712824133
https://doi.org/10.1023/a:1015712824133
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 309(10)
While it is well established that class-I antiarrhythmics block cardiac sodium channels, the mechanism of action of therapeutic levels of these drugs is not well understood. Using a combination of mathematical modeling and in vitro experiments, we st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4f4cbf535000cd4af0296ddda68a53
https://pubmed.ncbi.nlm.nih.gov/26342072
https://pubmed.ncbi.nlm.nih.gov/26342072